Results 61 to 70 of about 714,938 (290)

CT for estimating adequacy of lymph node dissection in patients with squamous cell carcinoma of the head and neck

Cancer Imaging, 2021
Background Indices obtained from lymph node dissection specimens, specifically lymph node yield (LNY) and lymph node ratio (LNR), have prognostic significance in the setting of head and neck squamous cell carcinoma (HNSCCa).
Christiaan A. Rees, Joshua H. Litchman, Xiaotian Wu, Mariah M. Servos, Darcy A. Kerr, Ryan J. Halter, David A. Pastel, Joseph A. Paydarfar   +7 more
doaj   +1 more source

Evaluation of lymph node counts in primary retroperitoneal lymph node dissection [PDF]

Cancer, 2010
AbstractBACKGROUND:Lymph node counts are a measure of quality assurance and are associated with prognosis for numerous malignancies. To date, investigations of lymph node counts in testis cancer are lacking.METHODS:By using the Memorial Sloan‐Kettering Testis Cancer database, the authors identified 255 patients who underwent primary retroperitoneal ...
R Houston, Thompson, Brett S, Carver, George J, Bosl, Dean, Bajorin, Robert, Motzer, Darren, Feldman, Victor E, Reuter, Joel, Sheinfeld   +7 more
openaire   +2 more sources

HD‐tDCS Restores Perivascular AQP4 Polarization via PPARγ Modulation to Enhance Glymphatic Clearance After Intracerebral Hemorrhage in Mice

Advanced Science, EarlyView.
HD‐tDCS promotes recovery after intracerebral hemorrhage by enhancing PPARγ‐dependent astrocyte remodeling in a mouse model of ICH. This process suppresses proinflammatory astrocytic activation, restores perivascular AQP4 repolarization, and improves glymphatic influx and efflux, thereby facilitating hematoma and perihematomal edema clearance and ...
Zhiming Li, Yingmei Zhang, Qianqian Tong, Zhitao Gong, Shanyu Zhang, Zhen Qian, Hui Zhang, Qian Yao, Qi Li   +8 more
wiley   +1 more source

Spatiotemporally Ultrasound‐Controlled Nanoparticles Reprogramming Immunostimulatory Antigen‐Presenting Cancer‐Associated Fibroblasts to Enhance Cancer Immunotherapy

Advanced Science, EarlyView.
We developed an ultrasound‐controlled biomimetic nanoplatform, mRNA/V@M NPs, to co‐deliver CD74 mRNA and V‐9302 for fibrotic TNBC therapy. CD74 mRNA reprograms myCAFs into antigen‐presenting apCAF cells through the CD74‐MHC II pathway, while V‐9302 induces ICD and activates MHC I‐CD8+ T cell immunity.
Chen Ai, Weikai Sun, Yuxuan Zhao, Daqian Sun, Ting Meng, Yafei Qi, Fengyang Jiang, Jintang Sun, Zhiliang Gao, Dexin Yu   +9 more
wiley   +1 more source

Applied anatomy of pelvic lymph nodes and its clinical significance for prostate cancer:a single-center cadaveric study

BMC Cancer, 2020
Background Pelvic lymph node dissection (PLND) is one of the most important steps in radical prostatectomy (RP). Not only can PLND provide accurate clinical staging to guide treatment after prostatectomy but PLND can also improve the prognosis of ...
Jia-Jun Chen, Zai-Sheng Zhu, Yi-Yi Zhu, Hong-Qi Shi   +3 more
doaj   +1 more source

Integrated Single‐Cell and TCR Profiling Reveals Protection‐Associated CD8+ T Cell Subsets Linked to Viral Control in PRRSV

Advanced Science, EarlyView.
PRRSV vaccine‐mediated protection is associated with clonally expanded cytotoxic CD8+ T cell subsets driven by viral structural proteins and supported by innate TLR4/TLR8 signaling and CD4+ T cell help, whereas non‐protective responses are characterized by dysfunctional exhausted‐like CD8+ T cells linked to poor viral control.
Can Kong, Siang Chen, Maolin Li, Meng Wang, Hailin Zhang, Bolun Zhou, Zhenhua Xie, Chen Wang, Peng Gao, Jianjun Luo, Hanchun Yang, Runsheng Chen, Dongdong Zhang, Jie Li, Jun Han   +14 more
wiley   +1 more source

CAUSES OF GASTRIC CANCER RECURRENCES IN PATIENTS AFTER RADICAL SURGERY

Инновационная медицина Кубани, 2019
Gastric cancer is one the most serious oncological pathologies and it occupies the third position in the structure of oncological mortality. Latest achievements in surgery for gastric cancer are linked to extended lymph node dissection (D2), still, long ...
A. G. Baryshev, V. A. Porhanov, A. J. Popov, A. N. Lischenko, N. V. Khachaturyan, D. A. Valyakis, M. V. Bodnya   +6 more
doaj   +2 more sources

Clinical Study on Prelaryngeal Lymph Node Metastasis in Papillary Thyroid Carcinoma

Cancer Management and Research, 2020
Jin-Xing Gong,1 Jian-Wei Gu,1 Feng Ji,1 Kun Li,1 Qi Zhu,1 Fang-Ying Gu,1 Yan Chen,1 Qing-Hai Ji2 1Department Four of Surgery, Kunshan Hospital of Traditional Chinese Medicine, Kunshan 215300, People’s Republic of China; 2Head & Neck Surgery ...
Gong JX, Gu JW, Ji F, Li K, Zhu Q, Gu FY, Chen Y, Ji QH   +7 more
doaj  

Extended lymph node dissection: bladder, kidney

, 2011
To present recent advances in the field of lymph node dissection (LND) in the context of bladder cancer, upper urinary tract urothelial carcinoma and renal cell carcinoma with focus on dissection ...
Zehnder, Pascal, Desai, Mihir, Pascal Zehnder, Mihir Desai   +3 more
core   +1 more source

Integrated Single‐Nucleus Multi‐Omics Atlases Reveal Lineage Plasticity and Regulatory Networks of Luminal Epithelial Cells During Mammary Gland Lactation and Involution

Advanced Science, EarlyView.
This study integrates single‐cell multi‐omics, spatial transcriptomics, and cross‐species comparative analyses to systematically characterize the cellular composition and differentiation trajectories of goat mammary epithelial cells, along with the gene regulatory networks and intercellular communication mechanisms governing these trajectories, thereby
Xiaoru Yan, Xiaoyu Mi, Guanghui Tan, Xinmei Li, Zhenliang Zhu, Zhenyu Wei, Huimei Fan, Yamei Wu, Tao Shi, Lingzhao Fang, Yuanpeng Gao, Yu Wang, Jun Liu   +12 more
wiley   +1 more source