Results 51 to 60 of about 278,243 (313)

Insights into the mechanisms of lymph node metastasis [PDF]

Cancer, 2003
AbstractThe mechanisms by which malignant tumors leave the primary tumor site, invade lymphatics, and metastasize to regional lymph nodes (RLNs) are complex and interrelated. Although the phenomenon of lymph node metastasis has been recognized for over 200 years, the exact mechanisms have only recently been the subject of intense interest and ...
openaire   +2 more sources

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Diagnostic Value of CT-detected Extramural Vessel Invasion in Lymph Node Metastasis of Gastric Cancer

CT Lilun yu yingyong yanjiu
Objective: To investigate the diagnostic value of extramural vessel invasion (EMVI) in multidetector row computed tomography (MDCT) of lymph node metastasis of gastric cancer.
Zhengqi ZHU, Shufeng DUAN, Haipeng GONG
doaj   +1 more source

Predictive Value of Depth of Invasion of Tongue Squamous Cell Carcinoma for Cervical Lymph Node Metastasis and Prognosis

Zhongliu Fangzhi Yanjiu, 2022
Objective To investigate the predictive value of depth of invasion (DOI) of tongue squamous cell carcinoma (TSCC) for cervical lymph node metastasis and prognosis. Methods We retrospectively analyzed the clinical and pathological data of 73 patients with
XIA Lili, ZHU Xinyi, ZHANG Xiwei, LI Zhengjiang, LIU Shaoyan, LU Haizhen, AN Changming   +6 more
doaj   +1 more source

The further assessment of a handheld Raman spectroscopy probe for the intraoperative diagnosis of axillary lymph nodes in breast cancer [PDF]

, 2012
Axillary sentinel lymph node biopsy plays an important role in breast cancer management in determining further surgical and medical treatment options.
Tydeman, C.
core  

Management of Multiple Mediastinal Lymph Node Metastasis in Synchronic Colorectal and Lung Carcinomas [PDF]

Metastasis of colorectal carcinomas to mediastinal lymph nodes is extremely rare. In this study, it is aimed to share our approach to mediastinal lymph nodes for treating colorectal carcinoma and lung carcinoma detected synchronously.
Büşra Özdemir Çiflik, Sebahattin Sefa Ermancık, Furkan Süral, Nevzat Kılıç, Koray Aydoğdu, Olcay Kandemir   +5 more
core   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

Risk factors for cervical lymph node metastasis in oropharyngeal cancer and its impact on prognosis

Brazilian Journal of Otorhinolaryngology
Objective: To understand the characteristics of cervical lymph node metastasis in Oropharyngeal Squamous Cell Carcinoma (OPSCC) patients, explore the risk factors for lymph node metastasis, and its impact on prognosis. Methods: Retrospective cohort study.
Li Zhang, Zhilin Li, Jing Wang, Chen Wang, Shuxin Wen   +4 more
doaj   +1 more source

Lymph Node Metastasis in a Gynecologic Malignancy

Yonsei Medical Journal, 2002
A radical hysterectomy was performed on patients with stage IA2 to IIB cervical cancer. For these patients, many histopathological parameters have been reported to be prognostic factors of cervical cancer, such as a pelvic lymph node (PLN) metastasis, the histological subtype, the tumor diameter, the depth of the stromal invasion, a lymph-vascular ...
Toshiharu, Kamura, Jin Dong, Jeon
openaire   +2 more sources

The use of Raman spectroscopy for the intra-operative assessment of axillary lymph nodes in breast cancer [PDF]

, 2012
Breast cancer remains a significant cause of morbidity and mortality. Assessment of the axillary lymph nodes is part of the staging of the disease. Advances in surgical management of breast cancer have seen a move towards intra-operative lymph node ...
Horsnell, Jonathan
core