Results 61 to 70 of about 960,720 (290)

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

Molecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic, Maria Concetta Vitale, Rita Siino, Emilia Di Giovanni, Carla Ferrante Bannera, Enrico Di Marco, Andrea Gottardo, Tancredi Didier Bazan Russo, Nadia Barraco, Alessandro Perez, Valerio Gristina, Antonio Galvano, Giuseppe Badalamenti, Antonio Russo, Viviana Bazan, Lorena Incorvaia   +15 more
wiley   +1 more source

Neonatal Melanoma with Lymph Node Metastasis

EJC Skin Cancer
Abstract. Congenital melanoma is a very rare condition defined as a melanoma recognized at or shortly after birth. It may arise de novo or from transplacental metastasis of maternal melanoma. In this case report, de novo primary congenital melanoma presented during the first four months of life, and was diagnosed by histopathological ...
Jevrić, Marko, Salatić, Igor, Brašanac, Dimitrije, Griewank, Klaus G, Hauschild, Axel, Schadendorf, Dirk, Stojanovic Milosavljevic, Miona, Filipović, Jelena, Denčić-Fekete, Marija, Sondak, Vernon, Žegarac, Milan, Kandolf, Lidija   +11 more
openaire   +1 more source

Trichilemmal carcinoma with lymph node metastasis.

Nishi Nihon Hifuka, 1985
53才男子の左大腿外側に発生し, 所属リンパ節転移を伴つたtrichilemmal carcinomaの1例を報告した。臨床上, Bowen癌を疑い生検により本症と確定診断を下した。組織学上, 腫瘤辺縁の局面ではfollicular Bowen’s diseaseの像を呈し, 腫瘤部ではtrichilemmal carcinomaの所見がみられた。リンパ節転移巣には, 原発巣と同様の組織所見が認められた。
TOMITA, Toshio, SUZUKI, Tadashi, SASAKI, Akira, ISHIKAWA, Kenji, TAJIMA, Kimiko, IKEDA, Shigeo   +5 more
openaire   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

Patterns of lymph node metastasis in level IIB and contralateral level VI for papillary thyroid carcinoma with pN1b and safety of low collar extended incision for neck dissection in level II

World Journal of Surgical Oncology, 2023
Objective To explore relevant clinical factors of level IIB and contralateral level VI lymph node metastasis and evaluate the safety of low-collar extended incision (LCEI) for lymph node dissection in level II for papillary thyroid carcinoma (PTC) with ...
Yudong Ning, Yuebai Liu, Dingfen Zeng, Yuqiu Zhou, Linjie Ma, Shuang Dong, Jianfeng Sheng, Gaosong Wu, Wen Tian, Yongcong Cai, Chao Li   +10 more
doaj   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Analysis of the relevant factors of lymph node metastasis in No.253 lymph node of rectal cancer patients

Cancer Treatment and Research Communications
Objective: Lymph node metastasis is the primary metastasis of colorectal cancer, and it is of positive significance to explore the characteristics and potential influencing factors of lymph node metastasis in colorectal cancer patients to guide the ...
Yu-Xi Gao, Shi-Xiang Pan, Fang Hu, Bo Li, Shou-Guang Wang   +4 more
doaj   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Macrophage-Related SPP1 as a Potential Biomarker for Early Lymph Node Metastasis in Lung Adenocarcinoma

Frontiers in Cell and Developmental Biology, 2021
Lymph node metastasis is a major factor that affects prognosis in patients with lung adenocarcinoma (LUAD). In some cases, lymph node metastasis has already occurred when the primary tumors are still small (i.e., early T stages), however, relevant ...
Bo Dong, Chunli Wu, Lan Huang, Yu Qi
doaj   +1 more source

Lymph Node Metastasis in a Gynecologic Malignancy

Yonsei Medical Journal, 2002
A radical hysterectomy was performed on patients with stage IA2 to IIB cervical cancer. For these patients, many histopathological parameters have been reported to be prognostic factors of cervical cancer, such as a pelvic lymph node (PLN) metastasis, the histological subtype, the tumor diameter, the depth of the stromal invasion, a lymph-vascular ...
Toshiharu, Kamura, Jin Dong, Jeon
openaire   +2 more sources