Results 111 to 120 of about 2,079,227 (402)

Segmentation of 3D High-frequency Ultrasound Images of Human Lymph Nodes Using Graph Cut with Energy Functional Adapted to Local Intensity Distribution [PDF]

arXiv, 2017
Previous studies by our group have shown that three-dimensional high-frequency quantitative ultrasound methods have the potential to differentiate metastatic lymph nodes from cancer-free lymph nodes dissected from human cancer patients. To successfully perform these methods inside the lymph node parenchyma, an automatic segmentation method is highly ...
arxiv  

Exosomes released by melanoma cells prepare sentinel lymph nodes for tumor metastasis.

Cancer Research, 2011
Exosomes are naturally occurring biological nanovesicles utilized by tumors to communicate signals to local and remote cells and tissues. Melanoma exosomes can incite a proangiogenic signaling program capable of remodeling tissue matrices. In this study,
Joshua L Hood, R. A. San, S. Wickline
semanticscholar   +1 more source

The PTTG1/VASP axis promotes oral squamous cell carcinoma metastasis by modulating focal adhesion and actin filaments

Molecular Oncology, EarlyView.
VASP was found to be overexpressed in metastatic oral squamous cell carcinoma (OSCC) tissues. Notably, PTTG1‐ and VASP‐deficient OSCC cells demonstrated suppressed metastatic properties by disrupting the interaction between the cytoskeleton and focal adhesion (FAs) in the filopodia region.
Suyeon Park, Sang Shin Lee, Shihyun Kim, Yeonjun Lee, Gyeonwon Park, Jung Oh Kim, Jongho Choi   +6 more
wiley   +1 more source

Preoperative ultrasound-guided injection of nanocarbon for central lymph node dissection in patients with papillary thyroid carcinoma

Scientific Reports
To explore better methods for tracing central lymph nodes in patients with papillary thyroid carcinoma by comparing the differences in the numbers and staining rates of central lymph nodes as well as the degree of nanocarbon extravasation between the ...
Ying Wang, Yan Si, Jing Wu, Hui Lu, Jifu Wei, Qiang Ding   +5 more
doaj   +1 more source

Ultrasonographic measurements of abdominal lymph nodes in growing puppies [PDF]

, 2016
The sonographic appearance of the normal abdominal lymph nodes in adult dogs has been well described, but the data in puppies are scarce and of poor quality. The aim of the current study was to evaluate any differences in abdominal lymph node sonographic
De Majo, M, La Pietra, A, Liotta, L, Macrì, F, Palumbo Piccionello, A, Pugliese, M.   +5 more
core   +1 more source

Decellularized Lymph Nodes as Scaffolds for Tissue Engineered Lymph Nodes [PDF]

Lymphatic Research and Biology, 2015
The lymphatic system is commonly injured during cancer treatment. However, despite the morbidity of these injuries, there are currently no options for replacing damaged lymphatics. The purpose of this study was to optimize methods for decellularization of murine lymph nodes (LN) and to determine if these scaffolds can be used to tissue engineer lymph ...
Babak J. Mehrara, Daniel A. Cuzzone, Swapna Ghanta, Seth Z. Aschen, Nicholas J. Albano   +4 more
openaire   +3 more sources

Targeted metabolomics reveals novel diagnostic biomarkers for colorectal cancer

Molecular Oncology, EarlyView.
This study employed targeted metabolomic profiling to identify 302 distinct metabolites present in platelet‐rich plasma (PRP), revealing aberrant metabolic profiles amongst individuals diagnosed with colorectal cancer (CRC). Compared to carcinoembryonic antigen (CEA) and cancer antigen 19‐9 (CA199), our metabolite panel showed improved sensitivity ...
Zuojian Hu, Fenglin Shen, Yang Liu, Ziqing Zhong, Yongling Chen, Zhiyuan Xia, Cuiju Mo, Hongxiu Yu   +7 more
wiley   +1 more source

Lymph Node Graph Neural Networks for Cancer Metastasis Prediction [PDF]

arXiv, 2021
Predicting outcomes, such as survival or metastasis for individual cancer patients is a crucial component of precision oncology. Machine learning (ML) offers a promising way to exploit rich multi-modal data, including clinical information and imaging to learn predictors of disease trajectory and help inform clinical decision making.
arxiv  

Lymph nodes go with the flow [PDF]

, 2018
In this issue, Bovay et al. (https://doi.org/10.1084/jem.20180217) invoke a compelling model of interplay between the venous and lymphatic vasculature in regulating the developmental genesis and early expansion of LNs.
Czepielewski, Rafael S, Randolph, Gwendalyn J   +1 more
core   +1 more source

Studies on the factors inducing metastasis of breast cancer to lymph node. I. Lymph flow in the thoracic wall [PDF]

, 1974
The mode of lymph flow from the breast to the regional lymph node was studied using 1llSAu colloid, to ascertain the concept of lymph node of Groups 1, 2, and 3. Lymph flow through the internal mammary nodes was found to be abundant.
Matsuo, Schinichiro
core   +1 more source