Results 111 to 120 of about 33,655 (235)
Cancer Medicine, Volume 15, Issue 4, April 2026.ABSTRACT Background Antiangiogenic combination therapy—antiangiogenic agents combined with immune checkpoint inhibitors and/or chemotherapy—has become an important treatment strategy for advanced driver‐negative non‐small cell lung cancer (NSCLC). We conducted a network meta‐analysis to compare efficacy and safety and identify optimal antiangiogenic ...
Zirui Li +8 more
wiley +1 more source
Lymphangioblasts in Embryonic Lymphangiogenesis
Lymphatic Research and Biology, 2003 The origin of the lymphatic endothelium, either from the venous system or mesenchymal lymphangioblasts, presents as a persistent controversy. Recently, highly specific markers of the lymphatic endothelium have been found, enabling us to reinvestigate the embryonic origin of the lymphatics.The homeobox transcription factor, Prox1, is expressed in ...
Wilting, Jörg +3 more
openaire +3 more sources
Frontiers in Oncology, 2019 Non-coding RNAs (ncRNAs), which do not encode proteins, have pivotal roles in manipulating gene expression in development, physiology, and pathology. Emerging data have shown that ncRNAs can regulate lymphangiogenesis, which refers to lymphatics deriving
Ming-xin Cao +5 more
doaj +1 more source
Clinical and Translational Allergy, Volume 16, Issue 4, April 2026.ABSTRACT Mast cells and basophils, historically defined by their pathogenic roles in allergic diseases and type I hypersensitivity, are increasingly recognized as influential participants in cancer biology. Emerging research in AllergoOncology highlights their plasticity, diverse functions, and significance beyond classical contributions to allergy ...
Jack Alder +6 more
wiley +1 more source
Lymphangiogenesis and colorectal cancer
Saudi Medical Journal, 2017 Lymphatic metastasis is an important event in the progress of metastasis in colorectal cancer (CRC). The purpose of this article is to assess the role of lymphangiogenesis on CRC. In peritumoral areas of CRC, the lymphatic microvessel density (LMVD) is higher than those in normal colorectal tissues.
Huang, Ciyou, Chen, Yigang
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Materials Today BioLymphangiogenesis, the formation of new lymphatic vessels from pre-existing vessels, is crucial for maintaining tissue homeostasis and immune function. Despite recent advances in understanding the molecular mechanisms regulating lymphangiogenesis, most ...
Dana E. Al-Ansari +5 more
doaj +1 more source
The Thoracic Lymphatic Vasculature: Interorgan Strategies to Achieve an Optimal Tissue Function
Comprehensive Physiology, Volume 16, Issue 2, April 2026.In the thorax, organ‐specific features such as stomata and submesothelial lacunae, pulmonary perivascular and peribronchial vessels, and subepicardial lymphatic network allow the thoracic lymphatics to perform as a dynamically regulated system able to exploit local mechanical forces and tissue‐specific architecture to maintain fluid and solute ...
Daniela Negrini +3 more
wiley +1 more source
Th2 Cytokines Inhibit Lymphangiogenesis
PLOS ONE, 2015 Lymphangiogenesis is the process by which new lymphatic vessels grow in response to pathologic stimuli such as wound healing, inflammation, and tumor metastasis. It is well-recognized that growth factors and cytokines regulate lymphangiogenesis by promoting or inhibiting lymphatic endothelial cell (LEC) proliferation, migration and differentiation. Our
Ira L Savetsky +8 more
openaire +4 more sources
Clinical and Translational Medicine, Volume 16, Issue 4, April 2026.Extracellular vesicles mediate melanoma progression by transferring biomolecules (proteins, nucleic acids) that reshape the tumour microenvironment, promote immune evasion and drive metastasis. They also serve as diagnostic biomarkers and engineered therapeutic carriers for targeted therapy.
Junshu Li +3 more
wiley +1 more source