Results 101 to 110 of about 33,655 (235)

Foxp3 is correlated with VEGF-C expression and lymphangiogenesis in cervical cancer

World Journal of Surgical Oncology, 2017
Background Recent observations revealed Foxp3 participated in the development of cervical cancer. Furthermore, Foxp3 has a vital function in the lymphatic metastasis of cervical cancer.
Jiabu Tang, Zheng Yang, Zhuo Wang, Zhen Li, Hongmei Li, Jinbao Yin, Min Deng, Wei Zhu, Chao Zeng   +8 more
doaj   +1 more source

Antibody-based antiangiogenic and antilymphangiogenic therapies to prevent tumor growth and progression [PDF]

, 2013
Blood and lymphatic vessel formation is an indispensable factor for cancer progression and metastasis. Therefore, various strategies designed to block angiogenesis and lymphangiogenesis are being investigated in the hope to arrest and reverse tumor ...
Bereta, Joanna, Bzowska, Monika, Klaus, Tomasz, Kulesza, Małgorzata, Mężyk-Kopeć, Renata, Próchnicki, Tomasz   +5 more
core   +1 more source

Metal‐Supramolecular Drug Delivery System Empowered Meningeal Lymphatic Vessels‐Bridged Intracranial‐Peripheral Dual Immune Modulation for Reversing Glioblastoma Immune Suppression

Advanced Science, Volume 13, Issue 22, 17 April 2026.
A novel metal‐supramolecular nanoplatform (FLM@VC) enables efficient brain delivery via meningeal lymphatic vessels (MLVs), bypassing the blood‐brain barrier (BBB) through subcutaneous administration. It reprograms tumor‐associated macrophages (TAMs) and remodels the MLVs to promote DC trafficking and CD8+ T cell activation.
Chenxi Zhang, Zhongsheng Xu, Xiaowen Xu, Zening Zhang, Ranran Luo, Pengchen Ren, Yingying Luo, Qiuchi Wu, Xinyu Liu, Guodong Liu, Xiaojing He, Yun Liu   +11 more
wiley   +1 more source

Adventitial lymphatic capillary expansion impacts on plaque T cell accumulation in atherosclerosis [PDF]

, 2017
During plaque progression, inflammatory cells progressively accumulate in the adventitia, paralleled by an increased presence of leaky vasa vasorum. We here show that next to vasa vasorum, also the adventitial lymphatic capillary bed is expanding during ...
Alitalo, Kari, Anisimov, Andrey, Biessen, Erik A. L., Daissormont, Isabelle T. M. N., Gijbels, Marion, Heeneman, Sylvia, Lindeman, Jan H. N., Nurmi, Harri, Otten, Jeroen J. T., Rademakers, Timo, Schober, Andreas, Theelen, Thomas L., Theodorou, Kosta, van der Vorst, Emiel P. C.   +13 more
core   +1 more source

FomA‐Containing Outer Membrane Vesicles of Fusobacterium Nucleatum Facilitate Bladder Cancer Lymphatic Metastasis via IL‐6‐Dependent M2b Macrophage Polarization

Advanced Science, Volume 13, Issue 23, 23 April 2026.
Urinary Fusobacterium nucleatum–derived outer membrane vesicles are shown to promote bladder cancer lymphatic metastasis. The vesicle protein FomA activates TLR2/NF‐κB signaling in tumor cells, induces IL‐6 secretion, and drives M2b macrophage polarization and VEGF‐C–dependent lymphangiogenesis, revealing a microbiota‐driven mechanism linking tumor ...
Wentai Shangguan, Weijia Li, Wenxue Huang, Jilin Wu, Yao Yu, Yiyao Huang, Lin Yang, Ming Xie, Qishen Yang, Jun Zheng, Yuexuan Zhu, Qi Sun, Biao Li, Leqian Li, Zongwei Wang, Jie Zhao, Peng Wu, Bisheng Cheng   +17 more
wiley   +1 more source

An overview of the focus of the International Gap Junction Conference 2017 and Future Perspectives [PDF]

, 2018
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Kwak, Brenda R., Martin, Patricia E.
core   +2 more sources

Vascularized Cardiac Tissue Engineering: From Advances in Biofabrication to Translational Applications

Advanced Science, Volume 13, Issue 23, 23 April 2026.
This review presents a process‐oriented framework for vascularized cardiac tissue engineering, highlighting how the coordinated design of cells, biomaterials, and biofabrication strategies enables the functional development or vascularized myocardium for disease modelling and drug discovery.
Yang Liu, Zijie Zhang, Hongbin Li, Lino Prados‐Martin, Huanhong Li, Feng Cheng, Xia Tu, Khoon S. Lim, Wanlu Li, Mian Wang   +9 more
wiley   +1 more source

Lymphedema and Therapeutic Lymphangiogenesis

BioMed Research International, 2013
Lymphedema is a disorder of the lymphatic vascular system characterized by impaired lymphatic return and swelling of the extremities. Lymphedema is divided into primary and secondary forms based on the underlying etiology. Despite substantial advances in both surgical and conservative techniques, therapeutic options for the management of lymphedema are
Yukihiro Saito, Hironori Nakagami, Yasufumi Kaneda, Ryuichi Morishita   +3 more
openaire   +2 more sources

Apelin promotes lymphangiogenesis and lymph node metastasis [PDF]

, 2015
Whereas the role of the G-protein-coupled APJ receptor and its ligand, apelin, in angiogenesis has been well documented, the ability of the apelin/APJ system to induce lymphangiogenesis and lymphatic metastasis has been largely unexplored.
Berger W, Berta, Judit, Döme, Balázs, Garay, Tamás, Groger M, Grusch M, Hegedűs, Balázs, Hoda MA, Klepetko W, Laszlo, Viktoria, Masri B, Paku, Sándor, Rozsas A, Rényi-Vámos, Ferenc István, Torok S, Tóvári, József   +15 more
core  

Clinical significance of VEGF-A, -C and -D expression in esophageal malignancies [PDF]

, 2005
Vascular endothelial growth factors ( VEGF)- A, - C and - D are members of the proangiogenic VEGF family of glycoproteins. VEGF-A is known to be the most important angiogenic factor under physiological and pathological conditions, while VEGF-C and VEGF-D
Ahn MJ, Baatar D, Banks RE, Berse B, Boucher Y, Coia LR, Dirix LY, Du JR, Gu ZP, Guo WZ, Hefler L, Hickey K, Hironaka S, Isaka N, Ishikawa M, Karpanen T, Kato H, Kitadai Y, Kitamura K, Koide N, Koukourakis MI, Kukk E, Kumar H, Lackey VL, Lewis CE, Li Z, Maniwa Y, Millikan KW, Mobius C, Nagata J, Nguyen M, Noguchi T, Nor JE, Ohtsu A, Roberts WG, Rockwell S, Roder JD, Salven P, Shih CH, Spence GM, Suit HD, Theunissen PH, Uchida S, Vogel SB, Wallner G, Weingartner K, Yamamoto Y, Yang B, Yeo KT   +48 more
core   +1 more source