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Embryonic lymphangiogenesis

Cell and Tissue Research, 1999
About 8-9 decades ago the development of embryonic lymphatics was studied intensively. Since then our knowledge has not considerably increased in this field, and it is still unknown whether lymphatics are derived by sprouting from veins, de novo from lymphangioblasts, or by both mechanisms.
Wilting, Jörg   +2 more
openaire   +3 more sources

A Fisheye View on Lymphangiogenesis

2013
Zebrafish have been widely used to study vasculogenesis and angiogenesis, and the vascular system is one of the most intensively studied organ systems in teleosts. It is a little surprising, therefore, that the development of the zebrafish lymphatic network has only been investigated in any detail for less than a decade now.
van Impel, Andreas   +1 more
openaire   +2 more sources

Inflammatory Triggers of Lymphangiogenesis

Lymphatic Research and Biology, 2003
Inflammation is the common denominator to the postnatal events that overlap with lymphatic vessel growth, or lymphangiogenesis. Undoubtedly, inflammation and accompanying fluid overload are cardinal factors in wound healing, lymphedema, the pathogenesis of some forms of lymphangiomatosis, and solid tumor lymphangiogenesis.
Carla, Mouta, Mélanie, Heroult
openaire   +2 more sources

Corneal angiogenesis and lymphangiogenesis

Current Opinion in Allergy & Clinical Immunology, 2012
The purpose of the present review is to describe new antilymphangiogenic treatment strategies and recent findings on strain-dependency of corneal lymphangiogenesis and the interdependency between blood and lymphatic vessel growth.Studies on mice have revealed that apart from haemangiogenesis, lymphangiogenesis can also differ markedly between several ...
Birgit, Regenfuss   +2 more
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Lymphangiogenesis in development and disease

Thrombosis and Haemostasis, 2007
SummaryThe lymphatic vascular system plays an important role in the maintenance of fluid homeostasis, in the afferent immune response, in the intestinal lipid uptake and in the metastatic spread of malignant cells. The recent discovery of specific markers and growth factors for lymphatic endothelium and the establishment of genetic mouse models with ...
Ruediger, Liersch, Michael, Detmar
openaire   +2 more sources

Signaling angiogenesis and lymphangiogenesis

Current Opinion in Cell Biology, 1998
Exciting progress has been made in elucidating the complex network of receptor-ligand interactions that regulate blood vessel growth. Understanding these control mechanisms is of interest not only because of their role in developmental biology, but because they provide potential therapeutic strategies for disease processes involving angiogenesis, such ...
E I, Korpelainen, K, Alitalo
openaire   +2 more sources

Molecular Mechanisms of Lymphangiogenesis

International Journal of Hematology, 2004
Although the process of vascular development has been well documented, little is understood about lymphatic vasculature formation, despite its importance in normal and pathologic conditions. The dysfunction or abnormal growth of lymphatic vessels is associated with lymphedema and cancer metastasis. The recent discovery of lymphangiogenic growth factors
Meiko, Takahashi   +2 more
openaire   +2 more sources

Cardiac Lymphangiogenesis in CVDs

Arteriosclerosis, Thrombosis, and Vascular Biology
Peer ...
Brakenhielm, Ebba   +2 more
openaire   +3 more sources

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