Results 11 to 20 of about 8,541 (196)

Lymphangioleiomyomatosis [PDF]

Klinicka Onkologie, 2019
Lymphangioleiomyomatosis (LAM) is a rare systemic disease that occurs sporadically (S/LAM) or as part of tuberous sclerosis (TS/LAM). LAM is characterized by proliferation of abnormal smooth muscle cells. This disease clinically manifests as dyspnea on exertion and pneumothorax.
Martina, Doubková, Marianna, Štefániková, Vladimír, Čan, Zdeněk, Merta, Marek, Svoboda   +4 more
openaire   +4 more sources

Lymphangioleiomyomatosis and Langerhans cell histiocytosis - two case reports from our practice [PDF]

Srpski Arhiv za Celokupno Lekarstvo, 2022
Introduction. Lymphangioleiomyomatosis and pulmonary Langerhans cell histiocytosis are the most common pulmonary cystic diseases. Although they differ in pathogenesis, they share several features.
Milenković Ana, Ilić Miroslav, Javorac Jovan, Savić Nevena, Lalić Nensi   +4 more
doaj   +1 more source

Effectiveness of pulmonary rehabilitation in lymphangioleiomyomatosis

Indian Journal of Respiratory Care, 2021
Lymphangioleiomyomatosis (LAM) is a cystic lung disease frequently associated with reduced exercise capacity, mostly affecting young women. The disease is characterized by progressive pulmonary cystic change, recurrent pneumothorax, chylous pleural ...
Manivel Arumugam, Senthil Dhanasekaran, Kancherla Roopa, Pitchaimani Govindharaj   +3 more
doaj   +1 more source

Tissue‐Engineered Disease Modeling of Lymphangioleiomyomatosis Exposes a Therapeutic Vulnerability to HDAC Inhibition

Advanced Science, 2023
Lymphangioleiomyomatosis (LAM) is a rare disease involving cystic lung destruction by invasive LAM cells. These cells harbor loss‐of‐function mutations in TSC2, conferring hyperactive mTORC1 signaling. Here, tissue engineering tools are employed to model
Adam Pietrobon, Julien Yockell‐Lelièvre, Nicole Melong, Laura J. Smith, Sean P. Delaney, Nadine Azzam, Chang Xue, Nishanth Merwin, Eric Lian, Alberto Camacho‐Magallanes, Carole Doré, Gabriel Musso, Lisa M. Julian, Arnold S. Kristof, Roger Y. Tam, Jason N. Berman, Molly S. Shoichet, William L. Stanford   +17 more
doaj   +1 more source

Microscopic precursor lesions of uterine lymphangioleiomyomatosis associated with incidental nodal lymphangioleiomyomatosis: A case report and discussion of pathogenesis

Human Pathology: Case Reports, 2020
A 47 yo woman underwent resection of an endometrial adenocarcinoma with pelvic lymph node biopsies. She was found to have incidental nodal lymphangioleiomyomatosis (LAM).
Charles M. Lombard
doaj   +1 more source

Airspace Enlargement with Fibrosis in a Young Heavy Smoker Mimicking Diffuse Cystic Lung Disease

Medicina, 2022
The widespread use of computed tomography (CT) has led to the increased recognition of cystic lung lesions. Multiple pulmonary cysts can be observed in heterogeneous disorders called diffuse cystic lung diseases (DCLDs), which include pulmonary ...
Kyungsoo Bae, Hyo Jung An, Kyung Nyeo Jeon   +2 more
doaj   +1 more source

A Clinical Case of Pulmonary Lymphangioleiomyomatosis

Туберкулез и болезни лёгких, 2022
The article describes a clinical case of pulmonary lymphangioleiomyomatosis (LAM) in a 44-year-old female Patient N., who has been suffering from this disease for a long time.
S. S. Kazakova, E. V. Аftaeva, Z. V. Zinovieva   +2 more
doaj   +1 more source

Refractory chylous effusions in lymphangioleiomyomatosis patient post lung transplant

SAGE Open Medical Case Reports, 2020
Lymphangioleiomyomatosis is a rare systemic disorder of unknown etiology that affects young women almost exclusively. Chylous effusions are known to be associated with lymphangioleiomyomatosis and may be difficult to treat.
Samuel Jacob, Mojahid Ali, Magdy M El-Sayed Ahmed, Maxim Itkin, Tathagat Narula, Si Pham, David Erasmus   +6 more
doaj   +1 more source

Possible Novel Therapeutic Targets in Lymphangioleiomyomatosis Treatment

Frontiers in Medicine, 2020
Lymphangioleiomyomatosis (LAM) is a rare systemic neoplastic disease that exclusively happens in women. Studies focusing on LAM and tuberous sclerosis complex (TSC) have made great progress in understanding the pathogenesis and searching for treatment ...
Xixi Song, Hui Cai, Chengyu Yang, Xiaomin Xue, Jian Wang, Yuqing Mo, Mengchan Zhu, Guiping Zhu, Ling Ye, Meiling Jin   +9 more
doaj   +1 more source

Desaturation-Distance Ratio During Submaximal and Maximal Exercise Tests and Its Association With Lung Function Parameters in Patients With Lymphangioleiomyomatosis

Frontiers in Medicine, 2021
Background: The desaturation–distance ratio (DDR), the ratio of the desaturation area to the distance walked, is a promising, reliable, and simple physiologic tool for functional evaluation in subjects with interstitial lung diseases ...
Douglas Silva Queiroz, Douglas Silva Queiroz, Cibele Cristine Berto Marques da Silva, Alexandre Franco Amaral, Martina Rodrigues Oliveira, Henrique Takachi Moriya, Carlos Roberto Ribeiro Carvalho, Bruno Guedes Baldi, Celso R. F. Carvalho   +8 more
doaj   +1 more source