Results 51 to 60 of about 13,250 (289)

Glutaredoxin‐1 promotes lymphangioleiomyomatosis progression through inhibiting Bim‐mediated apoptosis via COX2/PGE2/ERK pathway

Clinical and Translational Medicine, 2023
Background Lymphangioleiomyomatosis (LAM) is a female‐predominant interstitial lung disease, characterized by progressive cyst formation and respiratory failure.
Ya Feng, Tianjiao Li, Yin Li, Zhoujun Lin, Xiao Han, Xiaolin Pei, Yupeng Zhang, Fei Li, Juan Yang, Di Shao, Chenggang Li   +10 more
doaj   +1 more source

Mast Cell Tryptase Release Contributes to Disease Progression in Lymphangioleiomyomatosis.

American Journal of Respiratory and Critical Care Medicine, 2021
RATIONALE Lymphangioleiomyomatosis is a multisystem disease causing lung cysts and respiratory failure. Loss of tuberous sclerosis complex (TSC) gene function results in a clone of 'LAM cells' with dysregulated mTOR activity.
R. Babaei‐Jadidi, A. Dongre, Suzanne Miller, Marcos Castellanos Uribe, I. Stewart, Zoe M Thompson, A. Nateri, P. Bradding, S. May, D. Clements, S. Johnson   +10 more
semanticscholar   +1 more source

The benefit of indwelling pleural catheter with ambulatory pneumothorax device and autologous blood patch pleurodesis in lymphangioleiomyomatosis with persistent air leak

Respirology Case Reports, 2023
We report a 35‐year‐old woman who presented with dyspnoea and chest pain for 1 week. High‐resolution computed tomography (HRCT) thorax revealed bilateral pneumothoraces with diffuse lung cysts.
Boon Hau Ng, Hsueh Jing Low, Nik Nuratiqah Nik Abeed, Mas Fazlin Mohamad Jailaini, Mohamed Faisal Abdul Hamid, Andrea Ban Yu‐Lin   +5 more
doaj   +1 more source

Cell-Free DNA and CXCL10 Derived from Bronchoalveolar Lavage Predict Lung Transplant Survival. [PDF]

, 2019
Standard methods for detecting chronic lung allograft dysfunction (CLAD) and rejection have poor sensitivity and specificity and have conventionally required bronchoscopies and biopsies.
Damm, Izabella, Liberto, Juliane M, Sarwal, Minnie M, Sarwal, Reuben D, Sigdel, Tara K, Vanaudenaerde, Bart M, Verleden, Geert M, Verleden, Stijn E, Vos, Robin, Watson, Drew, Yang, Joshua YC, Zarinsefat, Arya   +11 more
core   +2 more sources

Tuberous sclerosis complex presenting as pulmonary lymphangioleiomyomatosis - a clinicoradiological diagnosis

The Pan African Medical Journal, 2015
Tuberous sclerosis complex (TSC) manifests predominantly as a neurocutaneous disorder. Lymphangioleiomyomatosis (LAM) is a rare pulmonary manifestation of TSC.
Kamini Gupta, Amit Goyal, Kavita Saggar, Avik Banerjee   +3 more
doaj   +1 more source

Lung function response and side effects to rapamycin for lymphangioleiomyomatosis: a prospective national cohort study [PDF]

, 2017
Rationale Mechanistic target of rapamycin inhibitors reduce loss of lung function in lymphangioleiomyomatosis (LAM), although their benefit varies between individuals.
Janet Bee, Johnson, Lam, McCormack, Quanjer, Sasongko, Sharon Fuller, Simon R Johnson, Suzanne Miller, Takada   +9 more
core   +2 more sources

A woman with dyspnea and recurrent pneumothorax: when dyspnea is not asthma

Journal of Community Hospital Internal Medicine Perspectives, 2020
Lymphangioleiomyomatosis (LAM) is a rare disease characterized by cystic lung lesions, lymphatic abnormalities, and angiomyolipomas. It can take a significant amount of time to diagnose LAM due to the vague symptoms of fatigue, progressive dyspnea ...
Anusha Chidharla, Matthew Sehring, Marisa Ayari Ascencio, Subramanyam Chittivelu   +3 more
doaj   +1 more source

Doxycycline reduces the migration of tuberous sclerosis complex-2 null cells - effects on RhoA-GTPase and focal adhesion kinase [PDF]

, 2015
& Sons Ltd and Foundation for Cellular and Molecular Medicine. Lymphangioleiomyomatosis (LAM) is associated with dysfunction of the tuberous sclerosis complex (TSC) leading to enhanced cell proliferation and migration.
Black, JL, Burgess, JK, Krymskaya, VP, Moir, LM, Ng, HY, Oliver, BGG   +5 more
core   +1 more source

Isolation and characterisation of lymphatic endothelial cells from lung tissues affected by lymphangioleiomyomatosis

Scientific Reports, 2021
Lymphangioleiomyomatosis (LAM) is a rare pulmonary disease characterised by the proliferation of smooth muscle-like cells (LAM cells), and an abundance of lymphatic vessels in LAM lesions.
Koichi Nishino, Y. Yoshimatsu, T. Muramatsu, Yasuhito Sekimoto, K. Mitani, Etsuko Kobayashi, Shouichi Okamoto, Hiroki Ebana, Yoshinori Okada, M. Kurihara, Kenji Suzuki, J. Inazawa, Kazuhisa Takahashi, T. Watabe, K. Seyama   +14 more
semanticscholar   +1 more source

Differential diagnosis of chylothorax in therapeutic practice

Терапевтический архив, 2021
The article is devoted to the differential diagnosis of chylous pleural effusion. The spectrum of traumatic and non-traumatic causes of chylothorax is discussed in detail.
Marina A. Makarova, Gulsara E. Baimakanova, Stanislav A. Krasovsky   +2 more
doaj   +1 more source