Results 251 to 260 of about 123,210 (310)

Evaluation of the details and importance of lymphatic, microvascular, and perineural invasion in patients with non-functioning pancreatic neuroendocrine neoplasms based on tumor size and the 2022 World Health Organization classification: a 23-year retrospective analysis. [PDF]

World J Surg Oncol
Izumo W, Kawaida H, Saito R, Nakata Y, Amemiya H, Maruyama S, Takiguchi K, Shoda K, Shiraishi K, Furuya S, Kawaguchi Y, Mochizuki K, Kondo T, Ichikawa D.   +13 more
europepmc   +1 more source

Cartilage‐Penetrating Framework Nucleic Acid Nanoparticles Ameliorate Osteoarthritis by Promoting Drug Delivery and Chondrocyte Uptake

Advanced Science, EarlyView.
Based on the poor cartilage penetration of tFNA, a novel tFNA‐2WL with excellent cartilage permeability and perfect chondrocyte endocytosis properties is designed and fabricated. As a result, tFNA‐2WL has a nearly seven‐fold increase in the penetration depth into the cartilage, with the same excellent cell entry properties as tFNA.
Kui Huang, Qiumei Li, Huixuan Lin, Qian Shen, Yaping Wu, Taoran Tian, Chuan Ma, Sirong Shi, Jingang Xiao, Yunfeng Lin   +9 more
wiley   +1 more source

Vascular endothelial growth factor signaling in health and disease: from molecular mechanisms to therapeutic perspectives. [PDF]

Signal Transduct Target Ther
Lee C, Kim MJ, Kumar A, Lee HW, Yang Y, Kim Y.   +5 more
europepmc   +1 more source

Congenital lymphatic dysplasia and severe bone disease in a term neonate with a novel homozygous PIEZO1 variant [PDF]

Elizabeth Ketchum, Charles L. Groomes, A Ghersi, Brian B. Graziose, Sharen C. Wilson, Sidney Zven, Rebecca L. Hicks, William A. Langley, Michael A. Reott, John P. Schacht, Elizabeth V. Schulz, Jerri Curtis   +11 more
openalex   +1 more source

Fragment Autoantigens Stimulated T‐Cell‐Immunotherapy (FAST) as a Fast Autologous Cancer Vaccine

Advanced Science, EarlyView.
A personalized whole tumor cell vaccine (FAST) is developed to address immunosuppressive tumor microenvironments and genomic instability‐driven heterogeneity. Irradiation and cryoablation‐treated tumor cells generate fragmented antigens (FAs) that activate broad‐spectrum antigen presentation via upregulated immunogenic cell death, MHC‐I, and damage ...
Yuan Li, Huiqin Chen, Qiaofeng Shen, Yingshuang Liu, Pingping Li, Yuqi Ma, Yugang Wang, Shengkai Li, Xueqing Yan, Liyu Liu, Jianwei Shuai, Min Wu, Qi Ouyang, Feng‐Ming (Spring) Kong, Gen Yang   +14 more
wiley   +1 more source

Persistent lymphatic filariasis transmission seven years after validation of elimination as a public health problem: a cross-sectional study in Tonga. [PDF]

Lancet Reg Health West Pac
Lawford HLS, Tukia ', Takai J, Sheridan S, Ward S, Jian H, Martin BM, 'Ofanoa R, Lau CL.   +8 more
europepmc   +1 more source

Lung lymphatic endothelial cells undergo inflammatory and prothrombotic changes in a model of chronic obstructive pulmonary disease [PDF]

Anjali Trivedi, Tyler M. Lu, Barbara D. Summers, Kihwan Kim, Alexander J. Rhee, Sean Houghton, Derek E. Byers, Raphaël Lis, Hasina Outtz Reed   +8 more
openalex   +1 more source

Nucleic Acid‐Locked Smart Carrier for Photothermal/Chemotherapy‐Amplified Immunogenic Cell Death to Enhance Systemic Antitumor Efficacy

Advanced Science, EarlyView.
Multiple therapeutic modalities combined in a synergistic way that can modulate different immune axes are demonstrated potentially effective in boosting immunotherapy. A nucleic acid‐locked smart carrier (NASC) performed as an “all‐in‐one” nanoplatform is constructed for efficient eliciting chemo‐ and photothermal‐amplified immunogenic cell death to ...
Jiayang Zhang, Tianyu Gai, Jiwei Wang, Yucai Wu, Si‐Ming Zeng, Dongyuan Zhao, Wei Li   +6 more
wiley   +1 more source

Placental transmogrification of the lung in <i>AKT1</i>-related Proteus syndrome. [PDF]

ERJ Open Res
Nakajima T, Nakatani Y, Kasajima R, Nakazato Y, Aruga T, Tokuyama W, Miyagi Y, Chida M.   +7 more
europepmc   +1 more source