VEGF-C promotes the development of lymphatics in bone and bone loss
Patients with Gorham-Stout disease (GSD) have lymphatic vessels in their bones and their bones gradually disappear. Here, we report that mice that overexpress VEGF-C in bone exhibit a phenotype that resembles GSD.
Devon Hominick+9 more
doaj +1 more source
The value of cytologic diagnostics in fast intraoperative diagnosis of mediastinal lymphadenopathy and pulmonary and mediastinal tumors [PDF]
Extemporary (EXT) analysis is unavoidable in establishing the tumor diagnosis, operability and the extent of the operation. Alternative approach is cytologic analysis which, because of its simple methodology, provides results even faster.
Tatomirović Željka+3 more
doaj +1 more source
The Lymphatic System in Health and Disease [PDF]
The lymphatic vascular system has an important role in the regulation of tissue pressure, immune surveillance and the absorption of dietary fat in the intestine. There is growing evidence that the lymphatic system also contributes to a number of diseases, such as lymphedema, cancer metastasis and different inflammatory disorders.
Leah N. Cueni, Michael Detmar
openaire +3 more sources
Genital manifestations of tropical diseases [PDF]
Genital symptoms in tropical countries and among returned travellers can arise from a variety of bacterial, protozoal, and helminthic infections which are not usually sexually transmitted.
Richens, J
core +2 more sources
Tratamento cirúrgico da ascite quilosa Surgical treatment of chylous ascites
A ascite quilosa é uma complicação rara após procedimentos cirúrgicos e trauma abdominal, apresentando elevada morbidade e difícil manejo. Nos casos refratários ao tratamento clínico habitual, o tratamento cirúrgico se impõe, apesar da baixa taxa de ...
Claudia Stein Gomes+5 more
doaj +1 more source
Pulmonary lymphatic function and its research progress in pulmonary diseases
The lymphatic system is a unidirectional network in which lymph fluid flows centripetally along a series of lymphatic channels and eventually into the veins, so the lymphatic system can also be considered an auxiliary part of the venous system and an ...
Kang Xuya+4 more
doaj +1 more source
Homeobox genes in normal and abnormal vasculogenesis [PDF]
Homeobox containing genes are a family of transcription factors regulating normal development and controlling primary cellular processes (cell identity, cell division and differentiation) recently enriched by the discovery of their interaction with ...
Cantile M+3 more
core +1 more source
The therapeutic efficacy and macrofilaricidal activity of doxycycline for the treatment of river blindness [PDF]
Background. Onchocerca volvulus and lymphatic filariae, causing river blindness and elephantiasis, depend on endosymbiotic Wolbachia bacteria for growth, development, fertility, and survival.
Achim Hoerauf+43 more
core +1 more source
Research Progress on Intracranial Lymphatic Circulation and Its Involvement in Disorders
The lymphatic system is an important part of the circulatory system, as an auxiliary system of the vein, which has the functions of immune defense, maintaining the stability of the internal environment, and regulating the pressure of the tissue.
Fan Chen, Xuan Xie, Liang Wang
doaj +1 more source
Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source