Results 301 to 310 of about 107,605 (342)

Advances in mucosal injury mechanisms in radiation‐induced esophagitis associated with thoracic radiotherapy

Precision Radiation Oncology, EarlyView.
There is no specific therapeutic drug regimen for radiation esophagitis. In previous studies, radiation esophagitis was considered a self‐limiting disease; however, current clinical approaches are limited to symptomatic treatment, which yields unsatisfactory therapeutic outcomes.
Hao Zhang, Liangxue Luo, Chaofen Zhao, Bibo Wu, Jing Zhang, Lingfeng Liu, Bing Lu, Shengfa Su   +7 more
wiley   +1 more source

Impact of Genomic Mutations on the Transcriptional Pathways and Tumor Microenvironment Landscape of Localized Early Prostate Cancer

The Prostate, EarlyView.
ABSTRACT Background The management of intermediate‐risk early prostate cancer (PCa) is challenging due to the difficulty in distinguishing indolent from aggressive tumors. This study explores the association between genomic alterations and the tumor and its microenvironment (TME) and implications for disease progression. Methods We performed multi‐omic
William Lautert‐Dutra, Camila M. Melo, Luiz P. Chaves, Francisco C. Souza, Vida Talebian, Cheryl Crozier, Mary Anne Quintayo, Linda Liao, Dan Dion, Fabiano P. Saggioro, Felipe S. Avante, Rodolfo B. dos Reis, Jeremy A. Squire, Jane Bayani   +13 more
wiley   +1 more source

Loss of meningeal lymphatic endothelial cells results in formation of a newly forming vascular network with scavenging function

Katharina Uphoff, Andreas van Impel, Lars Muhl, Martin Stehling, Christer Betsholtz, Stefan Schulte-Merker   +5 more
openalex   +1 more source

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Lymphatic endothelial cells of the lymph node

Nature Reviews Immunology, 2020
The influx and efflux of cells and antigens to and from the draining lymph nodes largely take place through the subcapsular, cortical and medullary sinus systems. Recent analyses in mice and humans have revealed unexpected diversity in the lymphatic endothelial cells, which form the distinct regions of the sinuses.
Sirpa Jalkanen, Marko Salmi
exaly   +3 more sources

Murine Dermal Lymphatic Endothelial Cell Isolation

Journal of Visualized Experiments, 2023
The lymphatic system participates in the regulation of immune surveillance, lipid absorption, and tissue fluid balance. The isolation of murine lymphatic endothelial cells is an important process for lymphatic research, as it allows the performance of in vitro and biochemical experiments on the isolated cells.
Racheal Grace, Akwii, Margarita, Lamprou, Maria, Georgomanoli, Andriana, Plevriti, Antonia, Marazioti, Athanasia, Mouzaki, George, Mattheolabakis, Constantinos M, Mikelis   +7 more
openaire   +2 more sources

Lymphatic endothelial cell inclusion bodies

Journal of Ultrastructure Research, 1980
Paracrystalline, compact tubular, and myeloid inclusion bodies were observed in endothelial cells from canine renal, mesenteric, and thoracic duct lymphatics. Paracrystalline inclusions were membrane bound and were composed of filaments organized into closely packed hexagons (18 nm across).
K H, Albertine, L M, Fox, C C, O'Morchoe
openaire   +2 more sources

Establishment of Rat Lymphatic Endothelial Cell Line

Microcirculation, 2003
The objective of the present study was to establish a rat lymphatic endothelial cell line and then to investigate the morphological and immunohistochemical properties of the cells.The lymphatic endothelial cells of rat thoracic ducts were isolated enzymatically by trypsin digestion and were cultured in endothelium growth medium (EGM)-2 in an atmosphere
Risuke, Mizuno, Yumiko, Yokoyama, Nobuyuki, Ono, Fumitaka, Ikomi, Toshio, Ohhashi   +4 more
openaire   +2 more sources

Gene expression profile of lymphatic endothelial cells

Cell Biology International, 2011
The lymphatic system was first described at around the same time as the blood circulation centuries ago, but the biological function elucidation of LECs (lymphatic endothelial cells) is far less than that of BVECs (blood vascular endothelial cells). Since the discovery of molecular markers for LECs and exploration of lymphatic role in tumour metastasis,
Peiliang, Wang, Yongbo, Cheng
openaire   +2 more sources

Lymphatic endothelial cells actively regulate prostate cancer cell invasion

NMR in Biomedicine, 2016
Lymphatic vessels serve as the primary route for metastatic spread to lymph nodes. However, it is not clear how interactions between cancer cells and lymphatic endothelial cells (LECs), especially within hypoxic microenvironments, affect the invasion of cancer cells.
Tariq, Shah, Flonne, Wildes, Samata, Kakkad, Dmitri, Artemov, Zaver M, Bhujwalla   +4 more
openaire   +2 more sources

Moving lymphatic endothelial cells about

Science, 2017
Vascular Biology Lymphatic vessels return fluid and immune cells from peripheral tissues back to the circulation. The growth of new lymphatic vessels and their remodeling are critical for clearing infection and, less helpfully, for metastasis of many cancer subtypes. Williams et al.
openaire   +1 more source