Results 1 to 10 of about 42,508 (298)

Mast cell modulation of the vascular and lymphatic endothelium. [PDF]

Blood, 2011
AbstractMast cells (MCs) promote a wide range of localized and systemic inflammatory responses. Their involvement in immediate as well as chronic inflammatory reactions at both local and distal sites points to an extraordinarily powerful immunoregulatory capacity with spatial and temporal versatility.
Kunder CA, St John AL, Abraham SN.
europepmc   +4 more sources

Harnessing chimeric antigen receptor macrophages against solid tumors

Cancer Communications, EarlyView.
Abstract Macrophages are prevalent in multiple tumors and exhibit diverse and potent functional activities. Therapeutic reprogramming of macrophage phenotypes represents a promising strategy for cancer immunotherapy. Engineering chimeric antigen receptors (CARs) to endow macrophages with anti‐tumor capacities demonstrated encouraging efficacy ...
Mengru Wang, Zhen Qin, Xiu‐Wu Bian, Yu Shi   +3 more
wiley   +1 more source

Mesenteric cystic lymphangioma in three adults. [PDF]

J Surg Case Rep
Boujguenna I, Chiboub N, Boukis F, Abdouh S, Fakhri Y.   +4 more
europepmc   +1 more source

Model‐Informed Drug Development Applications and Opportunities in mRNA‐LNP Therapeutics

Clinical Pharmacology &Therapeutics, EarlyView.
The utilization of lipid nanoparticles (LNP) for encapsulating mRNA has revolutionized the field of therapeutics, enabling the rapid development of COVID‐19 vaccines and cancer vaccines. However, the clinical development of mRNA‐LNP therapeutics faces numerous challenges due to their complex mechanisms of action and limited clinical experience.
Jiawei Zhou, Rohit Rao, Monica E. Shapiro, Nessy Tania, Cody Herron, Cynthia J. Musante, Jim H. Hughes   +6 more
wiley   +1 more source

A Darwinian approach to the development of the vascular system in the vertebrates. [PDF]

Clin Exp Med
Ribatti D.
europepmc   +1 more source

Effects of Cytokines (or Activating Factors) on Arterial Endothelial Cells. [PDF]

Int J Mol Sci
Dicks LMT.
europepmc   +1 more source

Cutaneous Lymphangioma Circumscriptum. [PDF]

Dermatol Pract Concept
Lei X, Bian K, Xie B.
europepmc   +1 more source

Genetic lineage tracing identifies intermediate mesoderm as a novel contributor to mammalian kidney lymphatics

Jafree DJ, Russell LG, Stathopoulou A, Rowan CJ, White AT, O’Riordan C, Kolatsi-Joannou M, Price KL, Ivins S, Ridge LA, Roberts C, Chandler JC, Wilson L, Moulding D, Siegenthaler J, Woolf AS, Riley PR, Ruhrberg C, Scambler PJ, Rosenblum ND, Long DA.   +20 more
europepmc   +1 more source

Uncovering the transcriptional hallmarks of endothelial cell aging via integrated single-cell analysis

Dobner S, Kleissl L, Tóth F, Paxton R, Yordanova I, Brazdilova K, Vanluyten C, Aizenshtadt A, Toth H, Burton J, Kopf A, Belyaeva V, Ferencevic K, Al-Nuaimi DA, Rendeiro AF, Bock C, Kalucka J, Krauss S, Osmanagic-Myers S, Ceulemans LJ, Stary G, Abdel Fattah AR, de Rooij LP.   +22 more
europepmc   +1 more source