Results 1 to 10 of about 39,644 (320)
Hematopoietic stem cells contribute to lymphatic endothelium. [PDF]
PLoS ONE, 2008 Although the lymphatic system arises as an extension of venous vessels in the embryo, little is known about the role of circulating progenitors in the maintenance or development of lymphatic endothelium.
Shuguang Jiang +6 more
doaj +10 more sources
Pannexin1 deletion in lymphatic endothelium affects lymphatic function in a sex‐dependent manner [PDF]
Physiological ReportsThe lymphatic network of capillaries and collecting vessels ensures tissue fluid homeostasis, absorption of dietary fats and trafficking of immune cells.
Avigail Ehrlich +5 more
doaj +5 more sources
Immunomodulatory properties of the lymphatic endothelium in the tumor microenvironment [PDF]
Frontiers in Immunology, 2023 The tumor microenvironment (TME) is an intricate complex and dynamic structure composed of various cell types, including tumor, stromal and immune cells.
Cristina Viúdez-Pareja +5 more
doaj +4 more sources
The Lymphatic Endothelium in the Context of Radioimmuno-Oncology. [PDF]
Cancers (Basel), 2022 The study of lymphatic tumor vasculature has been gaining interest in the context of cancer immunotherapy. These vessels constitute conduits for immune cells’ transit toward the lymph nodes, and they endow tumors with routes to metastasize to the lymph nodes and, from them, toward distant sites.
Suárez L +2 more
europepmc +5 more sources
Dendritic cell interactions with lymphatic endothelium. [PDF]
Lymphat Res Biol, 2013 Afferent lymphatic vessels fulfill essential immune functions by transporting leukocytes and lymph-borne antigen to draining lymph nodes (dLNs). An important cell type migrating through lymphatic vessels are dendritic cells (DCs). DCs reside in peripheral tissues like the skin, where they take up antigen and transport it via the lymphatic vascular ...
Russo E, Nitschké M, Halin C.
europepmc +7 more sources
Paraxial Mesoderm Is the Major Source of Lymphatic Endothelium. [PDF]
Dev Cell, 2019 Endothelial cells (ECs), which line blood and lymphatic vessels, are generally described to come from the lateral plate mesoderm despite experimental evidence for a broader source of origin, including the paraxial mesoderm (PXM). Current dogma suggests that following specification from mesoderm, local environmental cues establish the distinct molecular
Stone OA, Stainier DYR.
europepmc +7 more sources
microRNAs in the Lymphatic Endothelium: Master Regulators of Lineage Plasticity and Inflammation. [PDF]
Front Immunol, 2017 microRNAs (miRNAs) are highly conserved, small non-coding RNAs that regulate gene expression at the posttranscriptional level. They have crucial roles in organismal development, homeostasis, and cellular responses to pathological stress.
Yee D, Coles MC, Lagos D.
europepmc +8 more sources
Cellular Origins of the Lymphatic Endothelium: Implications for Cancer Lymphangiogenesis [PDF]
Frontiers in Physiology, 2020 The lymphatic system plays important roles in physiological and pathological conditions. During cancer progression in particular, lymphangiogenesis can exert both positive and negative effects.
Laura Gutierrez-Miranda, Karina Yaniv
doaj +5 more sources
Emerging roles of lymphatic endothelium in regulating adaptive immunity. [PDF]
J Clin Invest, 2014 Emerging research on the roles of stromal cells in modulating adaptive immune responses has included a new focus on lymphatic endothelial cells (LECs). LECs are presumably the first cells that come into direct contact with peripheral antigens, cytokines, danger signals, and immune cells travelling from peripheral tissues to lymph nodes.
Card CM, Yu SS, Swartz MA.
europepmc +6 more sources
The lymphatic endothelium of the avian wing is of somitic origin [PDF]
Developmental Dynamics, 2000 It has recently been shown that there are lymphangioblasts in the early avian wing bud, but fate map studies on the origin of these cells have not yet been performed. The lymphatics in the wings of 10-day-old chick and quail embryos are characterized by both the position along with all major blood vascular routes and by the Vascular Endothelial Growth ...
Wilting, Jörg +3 more
+6 more sources