Results 1 to 10 of about 593 (231)

Hematopoietic stem cells contribute to lymphatic endothelium.

PLoS ONE, 2008
BackgroundAlthough the lymphatic system arises as an extension of venous vessels in the embryo, little is known about the role of circulating progenitors in the maintenance or development of lymphatic endothelium.
Shuguang Jiang, Alexis S Bailey, Devorah C Goldman, John R Swain, Melissa H Wong, Philip R Streeter, William H Fleming   +6 more
doaj   +6 more sources

Pannexin1 deletion in lymphatic endothelium affects lymphatic function in a sex‐dependent manner

Physiological Reports
The lymphatic network of capillaries and collecting vessels ensures tissue fluid homeostasis, absorption of dietary fats and trafficking of immune cells.
Avigail Ehrlich, Graziano Pelli, Robert Pick, Linda Clochard, Filippo Molica, Brenda R. Kwak   +5 more
doaj   +5 more sources

Transcription Factor Control of Lymphatic Quiescence and Maturation of Lymphatic Neovessels in Development and Physiology

Frontiers in Physiology, 2021
The lymphatic system is a vascular system comprising modified lymphatic endothelial cells, lymph nodes and other lymphoid organs. The system has diverse, but critical functions in both physiology and pathology, and forms an interface between the blood ...
Zarah B. Tabrizi, Nada S. Ahmed, Joseph L. Horder, Sarah J. Storr, Andrew V. Benest   +4 more
doaj   +1 more source

Lymphatic Clearance of Immune Cells in Cardiovascular Disease

Cells, 2021
Recent advances in our understanding of the lymphatic system, its function, development, and role in pathophysiology have changed our views on its importance. Historically thought to be solely involved in the transport of tissue fluid, lipids, and immune
Christophe Ravaud, Nikita Ved, David G. Jackson, Joaquim Miguel Vieira, Paul R. Riley   +4 more
doaj   +1 more source

KSHV infection of endothelial precursor cells with lymphatic characteristics as a novel model for translational Kaposi's sarcoma studies.

PLoS Pathogens, 2023
Kaposi's sarcoma herpesvirus (KSHV) is the etiologic agent of Kaposi's sarcoma (KS), a hyperplasia consisting of enlarged malformed vasculature and spindle-shaped cells, the main proliferative component of KS.
Krista Tuohinto, Terri A DiMaio, Elina A Kiss, Pirjo Laakkonen, Pipsa Saharinen, Tara Karnezis, Michael Lagunoff, Päivi M Ojala   +7 more
doaj   +1 more source

Is It All about Endothelial Dysfunction? Focusing on the Alteration in Endothelial Integrity as a Key Determinant of Different Pathological Mechanisms

Biomedicines, 2022
The endothelium is composed of a monolayer of endothelial cells (ECs) covering the inner side of arterial, venous and lymphatic vessels [...]
Pasquale Ambrosino, Silvestro Ennio D’Anna, Guido Grassi, Mauro Maniscalco   +3 more
doaj   +1 more source

Coagulation in Lymphatic System

Frontiers in Cardiovascular Medicine, 2021
The lymphatic system maintains homeostasis of the internal environment between the cells in tissues and the blood circulation. The coagulation state of lymph is determined by conditions of coagulation factors and lymphatic vessels. Internal obliteration,
Wendi Zhang, Wendi Zhang, Wendi Zhang, Jiang Li, Jiangjiu Liang, Xiumei Qi, Jinghui Tian, Ju Liu, Ju Liu   +8 more
doaj   +1 more source

Endothelial Dysfunction: From a Pathophysiological Mechanism to a Potential Therapeutic Target

Biomedicines, 2021
The endothelium is considered the largest organ of the body, composed of a monolayer of endothelial cells (ECs) lining the interior surface of blood and lymphatic vessels [...]
Pasquale Ambrosino, Guido Grassi, Mauro Maniscalco   +2 more
doaj   +1 more source

Plasticity of blood- and lymphatic endothelial cells and marker identification. [PDF]

PLoS ONE, 2013
The distinction between lymphatic and blood vessels is biologically fundamental. Here we wanted to rigorously analyze the universal applicability of vascular markers and characteristics of the two widely used vascular model systems human microvascular ...
Johannes Keuschnigg, Sirkku Karinen, Kaisa Auvinen, Heikki Irjala, John-Patrick Mpindi, Olli Kallioniemi, Sampsa Hautaniemi, Sirpa Jalkanen, Marko Salmi   +8 more
doaj   +1 more source

Role of Transcriptional and Epigenetic Regulation in Lymphatic Endothelial Cell Development

Cells, 2022
The lymphatic system is critical for maintaining the homeostasis of lipids and interstitial fluid and regulating the immune cell development and functions.
Hyeonwoo La, Hyunjin Yoo, Young Bin Park, Nguyen Xuan Thang, Chanhyeok Park, Seonho Yoo, Hyeonji Lee, Youngsok Choi, Hyuk Song, Jeong Tae Do, Kwonho Hong   +10 more
doaj   +1 more source