Results 1 to 10 of about 22,320 (127)

Shape and Function of Interstitial Chemokine CCL21 Gradients Are Independent of Heparan Sulfates Produced by Lymphatic Endothelium [PDF]

Frontiers in Immunology, 2021
Gradients of chemokines and growth factors guide migrating cells and morphogenetic processes. Migration of antigen-presenting dendritic cells from the interstitium into the lymphatic system is dependent on chemokine CCL21, which is secreted by ...
Kari Vaahtomeri, Kari Vaahtomeri, Christine Moussion, Robert Hauschild, Michael Sixt   +4 more
doaj   +3 more sources

Connexin-45 is expressed in mouse lymphatic endothelium and required for lymphatic valve function [PDF]

JCI Insight
The expression and functional relevance of the gap junction molecule connexin-45 (Cx45; GJC1) in lymphatic endothelium were not previously known. We found that Cx45 was expressed widely in the endothelium of murine lymphatics, in both valve and nonvalve ...
Michael J. Davis, Jorge A. Castorena-Gonzalez, Min Li, Scott D. Zawieja, Alex M. Simon, Xin Geng, R. Sathish Srinivasan   +6 more
doaj   +4 more sources

Pannexin1 deletion in lymphatic endothelium affects lymphatic function in a sex‐dependent manner [PDF]

Physiological Reports
The lymphatic network of capillaries and collecting vessels ensures tissue fluid homeostasis, absorption of dietary fats and trafficking of immune cells.
Avigail Ehrlich, Graziano Pelli, Robert Pick, Linda Clochard, Filippo Molica, Brenda R. Kwak   +5 more
doaj   +3 more sources

Immunomodulatory properties of the lymphatic endothelium in the tumor microenvironment [PDF]

Frontiers in Immunology, 2023
The tumor microenvironment (TME) is an intricate complex and dynamic structure composed of various cell types, including tumor, stromal and immune cells.
Cristina Viúdez-Pareja, Cristina Viúdez-Pareja, Ewa Kreft, Ewa Kreft, Melissa García-Caballero, Melissa García-Caballero   +5 more
doaj   +2 more sources

Cellular Origins of the Lymphatic Endothelium: Implications for Cancer Lymphangiogenesis [PDF]

Frontiers in Physiology, 2020
The lymphatic system plays important roles in physiological and pathological conditions. During cancer progression in particular, lymphangiogenesis can exert both positive and negative effects.
Laura Gutierrez-Miranda, Karina Yaniv
doaj   +2 more sources

Tumour cells express functional lymphatic endothelium-specific hyaluronan receptor in vitro and in vivo: Lymphatic mimicry promotes oral oncogenesis? [PDF]

Oncogenesis, 2021
Karinen S, Juurikka K, Hujanen R, Wahbi W, Hadler-Olsen E, Svineng G, Eklund KK, Salo T, Åström P, Salem A.   +9 more
europepmc   +3 more sources

mTOR-Dependent Stimulation of IL20RA Orchestrates Immune Cell Trafficking through Lymphatic Endothelium in Patients with Crohn’s Disease [PDF]

Cells, 2019
Crohn’s disease (CD) is a chronic inflammatory condition that can affect different portions of the gastrointestinal tract. Lymphatic drainage was demonstrated to be dysfunctional in CD pathogenesis, ultimately causing the failure of the resolution ...
Federica Ungaro, Valentina Garlatti, Luca Massimino, Antonino Spinelli, Michele Carvello, Matteo Sacchi, Salvatore Spanò, Gaia Colasante, Nicholas Valassina, Stefania Vetrano, Alberto Malesci, Laurent Peyrin-Biroulet, Silvio Danese, Silvia D’Alessio   +13 more
doaj   +2 more sources

microRNAs in the Lymphatic Endothelium: Master Regulators of Lineage Plasticity and Inflammation. [PDF]

Front Immunol, 2017
Yee D, Coles MC, Lagos D.
europepmc   +3 more sources

The Lymphatic Endothelium in the Context of Radioimmuno-Oncology. [PDF]

Cancers (Basel), 2022
Suárez L, Rodríguez-Ruiz ME, Rouzaut A.   +2 more
europepmc   +3 more sources

Sphingosine 1-phosphate-regulated transcriptomes in heterogenous arterial and lymphatic endothelium of the aorta. [PDF]

Elife, 2020
Engelbrecht E, Levesque MV, He L, Vanlandewijck M, Nitzsche A, Niazi H, Kuo A, Singh SA, Aikawa M, Holton K, Proia RL, Kono M, Pu WT, Camerer E, Betsholtz C, Hla T.   +15 more
europepmc   +2 more sources