Results 1 to 10 of about 24,595 (195)
Immunomodulatory properties of the lymphatic endothelium in the tumor microenvironment [PDF]
Frontiers in Immunology, 2023 The tumor microenvironment (TME) is an intricate complex and dynamic structure composed of various cell types, including tumor, stromal and immune cells.
Cristina Viúdez-Pareja +5 more
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Connexin-45 is expressed in mouse lymphatic endothelium and required for lymphatic valve function [PDF]
JCI InsightThe expression and functional relevance of the gap junction molecule connexin-45 (Cx45; GJC1) in lymphatic endothelium were not previously known. We found that Cx45 was expressed widely in the endothelium of murine lymphatics, in both valve and nonvalve ...
Michael J. Davis +6 more
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Pannexin1 deletion in lymphatic endothelium affects lymphatic function in a sex‐dependent manner [PDF]
Physiological ReportsThe lymphatic network of capillaries and collecting vessels ensures tissue fluid homeostasis, absorption of dietary fats and trafficking of immune cells.
Avigail Ehrlich +5 more
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Cellular Origins of the Lymphatic Endothelium: Implications for Cancer Lymphangiogenesis [PDF]
Frontiers in Physiology, 2020 The lymphatic system plays important roles in physiological and pathological conditions. During cancer progression in particular, lymphangiogenesis can exert both positive and negative effects.
Laura Gutierrez-Miranda, Karina Yaniv
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Shape and Function of Interstitial Chemokine CCL21 Gradients Are Independent of Heparan Sulfates Produced by Lymphatic Endothelium [PDF]
Frontiers in Immunology, 2021 Gradients of chemokines and growth factors guide migrating cells and morphogenetic processes. Migration of antigen-presenting dendritic cells from the interstitium into the lymphatic system is dependent on chemokine CCL21, which is secreted by ...
Kari Vaahtomeri +4 more
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Meningeal lymphatic-associated brain swelling in acute stroke. [PDF]
PLoS ONEBrain meninges contain lymphatic vessels that play roles in clearance of extracellular solute in the central nervous system. But, whether and how the system is involved in acute stroke remains to be fully explored.
Rohan Mahesh Patil +9 more
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Frontiers in Physiology, 2021 The lymphatic system is a vascular system comprising modified lymphatic endothelial cells, lymph nodes and other lymphoid organs. The system has diverse, but critical functions in both physiology and pathology, and forms an interface between the blood ...
Zarah B. Tabrizi +4 more
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Lymphatic Clearance of Immune Cells in Cardiovascular Disease
Cells, 2021 Recent advances in our understanding of the lymphatic system, its function, development, and role in pathophysiology have changed our views on its importance. Historically thought to be solely involved in the transport of tissue fluid, lipids, and immune
Christophe Ravaud +4 more
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PLoS Pathogens, 2023 Kaposi's sarcoma herpesvirus (KSHV) is the etiologic agent of Kaposi's sarcoma (KS), a hyperplasia consisting of enlarged malformed vasculature and spindle-shaped cells, the main proliferative component of KS.
Krista Tuohinto +7 more
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Biomedicines, 2022 The endothelium is composed of a monolayer of endothelial cells (ECs) covering the inner side of arterial, venous and lymphatic vessels [...]
Pasquale Ambrosino +3 more
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