Results 11 to 20 of about 23,353 (279)

Direct specification of lymphatic endothelium from mesenchymal progenitors. [PDF]

Nat Cardiovasc Res
Abstract During embryogenesis, endothelial cells (ECs) are generally described to arise from a common pool of progenitors termed angioblasts, which diversify through iterative steps of differentiation to form functionally distinct subtypes of ECs.
Lupu IE, Grainger DE, Kirschnick N, Weischer S, Zhao E, Martinez-Corral I, Schoofs H, Vanhollebeke M, Jones G, Godwin J, Forrow A, Lahmann I, Riley PR, Zobel T, Alitalo K, Mäkinen T, Kiefer F, Stone OA.   +17 more
europepmc   +7 more sources

Lymphatic endothelium in health and disease [PDF]

Cell and Tissue Research, 2008
ISSN:1432 ...
Giorgia Jurisic, Michael Detmar
openalex   +5 more sources

Culturing purifies murine lymph node lymphatic endothelium. [PDF]

Lymphat Res Biol, 2014
Lymph node (LN) lymphatic sinuses transport lymph, cells, and antigens from the periphery through the LN. The lymphatic endothelium lining these sinuses appears to be an important contributor to the lymph node immune response. It has been challenging to obtain sufficient LN lymphatic endothelial cells for investigation of their functions, as they are ...
Jordan-Williams KL, Ruddell A.
europepmc   +4 more sources

Emerging roles of lymphatic endothelium in regulating adaptive immunity [PDF]

Journal of Clinical Investigation, 2014
Emerging research on the roles of stromal cells in modulating adaptive immune responses has included a new focus on lymphatic endothelial cells (LECs). LECs are presumably the first cells that come into direct contact with peripheral antigens, cytokines, danger signals, and immune cells travelling from peripheral tissues to lymph nodes.
Catherine M. Card, Shann S. Yu, Melody A. Swartz   +2 more
openalex   +3 more sources

Mast cell modulation of the vascular and lymphatic endothelium [PDF]

Blood, 2011
AbstractMast cells (MCs) promote a wide range of localized and systemic inflammatory responses. Their involvement in immediate as well as chronic inflammatory reactions at both local and distal sites points to an extraordinarily powerful immunoregulatory capacity with spatial and temporal versatility.
Christian A. Kunder, Ashley L. St. John, Soman N. Abraham   +2 more
openalex   +4 more sources

Meningeal lymphatic-associated brain swelling in acute stroke. [PDF]

PLoS ONE
Brain meninges contain lymphatic vessels that play roles in clearance of extracellular solute in the central nervous system. But, whether and how the system is involved in acute stroke remains to be fully explored.
Rohan Mahesh Patil, Dong Bin Back, Gen Hamanaka, Rakhi Desai, Ayumi Hayakawa, Su Jing Chan, Bum Ju Ahn, Giuseppe Pignataro, Kazuhide Hayakawa, Elga Esposito   +9 more
doaj   +2 more sources

Tumour cells express functional lymphatic endothelium-specific hyaluronan receptor in vitro and in vivo: Lymphatic mimicry promotes oral oncogenesis? [PDF]

Oncogenesis, 2021
Karinen S, Juurikka K, Hujanen R, Wahbi W, Hadler-Olsen E, Svineng G, Eklund KK, Salo T, Åström P, Salem A.   +9 more
europepmc   +3 more sources

Apelin modulates pathological remodeling of lymphatic endothelium after myocardial infarction. [PDF]

JCI Insight, 2017
Lymphatic endothelium serves as a barrier to control fluid balance and immune cell trafficking to maintain tissue homeostasis. Long-term alteration of lymphatic vasculature promotes edema and fibrosis, which is an aggravating factor in the onset of cardiovascular diseases such as myocardial infarction. Apelin is a bioactive peptide that plays a central
Tatin F, Renaud-Gabardos E, Godet AC, Hantelys F, Pujol F, Morfoisse F, Calise D, Viars F, Valet P, Masri B, Prats AC, Garmy-Susini B.   +11 more
europepmc   +5 more sources

Direct specification of lymphatic endothelium from non-venous angioblasts [PDF]

, 2022
Lupu I, Kirschnick N, Weischer S, Martinez-Corral I, Forrow A, Lahmann I, Riley PR, Zobel T, Makinen T, Kiefer F, Stone OA.   +10 more
europepmc   +2 more sources

Lymphatic Endothelium Forms Integrin-Engaging 3D Structures during DC Transit across Inflamed Lymphatic Vessels [PDF]

Journal of Investigative Dermatology, 2013
Dendritic cell (DC) transmigration across the lymphatic endothelium is critical for the initiation and sustenance of immune responses. Under noninflammatory conditions, DC transit across the lymphatic endothelial cell (LEC) has been shown to be integrin independent.
Álvaro Teijeira, Saray Garasa, Rafael Peláez, Arantza Azpilikueta, Carmen Ochoa, Diego Marré, Magda Rodrigues, Carlos Alfaro, Cristina Aubá, Salvatore Valitutti, Ignacio Melero, Ana Rouzaut   +11 more
openalex   +3 more sources