Results 11 to 20 of about 23,592 (245)

Culturing purifies murine lymph node lymphatic endothelium. [PDF]

open access: yesLymphat Res Biol, 2014
Lymph node (LN) lymphatic sinuses transport lymph, cells, and antigens from the periphery through the LN. The lymphatic endothelium lining these sinuses appears to be an important contributor to the lymph node immune response. It has been challenging to obtain sufficient LN lymphatic endothelial cells for investigation of their functions, as they are ...
Jordan-Williams KL, Ruddell A.
europepmc   +4 more sources

Emerging roles of lymphatic endothelium in regulating adaptive immunity. [PDF]

open access: yesJ Clin Invest, 2014
Emerging research on the roles of stromal cells in modulating adaptive immune responses has included a new focus on lymphatic endothelial cells (LECs). LECs are presumably the first cells that come into direct contact with peripheral antigens, cytokines, danger signals, and immune cells travelling from peripheral tissues to lymph nodes.
Card CM, Yu SS, Swartz MA.
europepmc   +4 more sources

Safeguarding lymphatic identity: cooperative Erg and Fli1 activity in lymphatic vascular homeostasis [PDF]

open access: yesThe Journal of Clinical Investigation
Although transcriptional programs driving lymphatic endothelial cell (LEC) specification are being increasingly characterized, far less is known about the postnatal mechanisms that preserve lymphatic vessel identity and function. In this issue of the JCI,
Kelly de Korodi, Tatiana V. Petrova
doaj   +2 more sources

Lymphatic endothelium [PDF]

open access: yesThe Journal of Cell Biology, 2003
The lymphatic microvasculature is uniquely adapted for the continuous removal of interstitial fluid and proteins, and is an important point of entry for leukocytes and tumor cells. The traditional view that lymphatic capillaries are passive participants in these tasks is currently being challenged.
Michael S. Pepper, Mihaela Skobe
openaire   +3 more sources

Transcription Factor Control of Lymphatic Quiescence and Maturation of Lymphatic Neovessels in Development and Physiology

open access: yesFrontiers in Physiology, 2021
The lymphatic system is a vascular system comprising modified lymphatic endothelial cells, lymph nodes and other lymphoid organs. The system has diverse, but critical functions in both physiology and pathology, and forms an interface between the blood ...
Zarah B. Tabrizi   +4 more
doaj   +1 more source

Lymphatic Clearance of Immune Cells in Cardiovascular Disease

open access: yesCells, 2021
Recent advances in our understanding of the lymphatic system, its function, development, and role in pathophysiology have changed our views on its importance. Historically thought to be solely involved in the transport of tissue fluid, lipids, and immune
Christophe Ravaud   +4 more
doaj   +1 more source

Lymphatic endothelium in health and disease [PDF]

open access: yesCell and Tissue Research, 2008
ISSN:1432 ...
Jurisic, Giorgia, Detmar, Michael
openaire   +4 more sources

KSHV infection of endothelial precursor cells with lymphatic characteristics as a novel model for translational Kaposi's sarcoma studies.

open access: yesPLoS Pathogens, 2023
Kaposi's sarcoma herpesvirus (KSHV) is the etiologic agent of Kaposi's sarcoma (KS), a hyperplasia consisting of enlarged malformed vasculature and spindle-shaped cells, the main proliferative component of KS.
Krista Tuohinto   +7 more
doaj   +1 more source

Is It All about Endothelial Dysfunction? Focusing on the Alteration in Endothelial Integrity as a Key Determinant of Different Pathological Mechanisms

open access: yesBiomedicines, 2022
The endothelium is composed of a monolayer of endothelial cells (ECs) covering the inner side of arterial, venous and lymphatic vessels [...]
Pasquale Ambrosino   +3 more
doaj   +1 more source

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