Results 21 to 30 of about 400,241 (273)

Homodimerization of the Lymph Vessel Endothelial Receptor LYVE-1 through a Redox-labile Disulfide Is Critical for Hyaluronan Binding in Lymphatic Endothelium*

open access: yesJournal of Biological Chemistry, 2016
The lymphatic vessel endothelial receptor LYVE-1 is implicated in the uptake of hyaluronan (HA) and trafficking of leukocytes to draining lymph nodes. Yet LYVE-1 has only weak affinity for hyaluronan and depends on receptor clustering and higher order ...
Omer Dushek   +2 more
exaly   +2 more sources

The Lymphatic Endothelium in the Context of Radioimmuno-Oncology. [PDF]

open access: yesCancers (Basel), 2022
The study of lymphatic tumor vasculature has been gaining interest in the context of cancer immunotherapy. These vessels constitute conduits for immune cells’ transit toward the lymph nodes, and they endow tumors with routes to metastasize to the ...
Suárez L   +2 more
europepmc   +2 more sources

Transcription Factor Control of Lymphatic Quiescence and Maturation of Lymphatic Neovessels in Development and Physiology

open access: yesFrontiers in Physiology, 2021
The lymphatic system is a vascular system comprising modified lymphatic endothelial cells, lymph nodes and other lymphoid organs. The system has diverse, but critical functions in both physiology and pathology, and forms an interface between the blood ...
Zarah B. Tabrizi   +4 more
doaj   +1 more source

Lymphatic Clearance of Immune Cells in Cardiovascular Disease

open access: yesCells, 2021
Recent advances in our understanding of the lymphatic system, its function, development, and role in pathophysiology have changed our views on its importance. Historically thought to be solely involved in the transport of tissue fluid, lipids, and immune
Christophe Ravaud   +4 more
doaj   +1 more source

KSHV infection of endothelial precursor cells with lymphatic characteristics as a novel model for translational Kaposi's sarcoma studies.

open access: yesPLoS Pathogens, 2023
Kaposi's sarcoma herpesvirus (KSHV) is the etiologic agent of Kaposi's sarcoma (KS), a hyperplasia consisting of enlarged malformed vasculature and spindle-shaped cells, the main proliferative component of KS.
Krista Tuohinto   +7 more
doaj   +1 more source

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