Antigen archiving by lymph node stroma: A novel function for the lymphatic endothelium. [PDF]
Eur J Immunol, 2015 Kedl RM, Tamburini BA.
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Culturing purifies murine lymph node lymphatic endothelium. [PDF]
Lymphat Res Biol, 2014 Lymph node (LN) lymphatic sinuses transport lymph, cells, and antigens from the periphery through the LN. The lymphatic endothelium lining these sinuses appears to be an important contributor to the lymph node immune response. It has been challenging to obtain sufficient LN lymphatic endothelial cells for investigation of their functions, as they are ...
Jordan-Williams KL, Ruddell A.
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Apelin modulates pathological remodeling of lymphatic endothelium after myocardial infarction. [PDF]
JCI Insight, 2017 Lymphatic endothelium serves as a barrier to control fluid balance and immune cell trafficking to maintain tissue homeostasis. Long-term alteration of lymphatic vasculature promotes edema and fibrosis, which is an aggravating factor in the onset of ...
Tatin F +11 more
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The Intestinal Lymphatic System: Functions and Metabolic ImplicationsSummary [PDF]
Cellular and Molecular Gastroenterology and Hepatology, 2019 The lymphatic system of the gut plays important roles in the transport of dietary lipids, as well as in immunosurveillance and removal of interstitial fluid.
Vincenza Cifarelli, Anne Eichmann
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Insulin resistance disrupts cell integrity, mitochondrial function, and inflammatory signaling in lymphatic endothelium. [PDF]
Microcirculation, 2018 Lymphatic vessel dysfunction and increased lymph leakage have been directly associated with several metabolic diseases. However, the underlying cellular mechanisms causing lymphatic dysfunction have not been determined. Aberrant insulin signaling affects
Lee Y +3 more
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Lymphatic endothelium in health and disease [PDF]
Cell and Tissue Research, 2018 The lymphatic vascular system has an important role in the maintenance of tissue fluid pressure homeostasis, in the mediation of the afferent immune response via recruitment of antigen-presenting cells toward draining lymph nodes, and in the intestinal ...
Detmar, Michael, Jurisic, Giorgia
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T Cell Migration from Inflamed Skin to Draining Lymph Nodes Requires Intralymphatic Crawling Supported by ICAM-1/LFA-1 Interactions [PDF]
Cell Reports, 2017 T cells are the most abundant cell type found in afferent lymph, but their migration through lymphatic vessels (LVs) remains poorly understood. Performing intravital microscopy in the murine skin, we imaged T cell migration through afferent LVs in vivo ...
Alvaro Teijeira +10 more
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Mast cell modulation of the vascular and lymphatic endothelium. [PDF]
Blood, 2011 AbstractMast cells (MCs) promote a wide range of localized and systemic inflammatory responses. Their involvement in immediate as well as chronic inflammatory reactions at both local and distal sites points to an extraordinarily powerful immunoregulatory capacity with spatial and temporal versatility.
Kunder CA, St John AL, Abraham SN.
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The lymphatic endothelium of the avian wing is of somitic origin [PDF]
Developmental Dynamics, 2000 It has recently been shown that there are lymphangioblasts in the early avian wing bud, but fate map studies on the origin of these cells have not yet been performed. The lymphatics in the wings of 10-day-old chick and quail embryos are characterized by both the position along with all major blood vascular routes and by the Vascular Endothelial Growth ...
Jörg Wilting +3 more
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