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Lymphatic endothelium in health and disease [PDF]
ISSN:1432 ...
Jurisic, Giorgia, Detmar, Michael
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Emerging roles of lymphatic endothelium in regulating adaptive immunity [PDF]
Emerging research on the roles of stromal cells in modulating adaptive immune responses has included a new focus on lymphatic endothelial cells (LECs). LECs are presumably the first cells that come into direct contact with peripheral antigens, cytokines, danger signals, and immune cells travelling from peripheral tissues to lymph nodes.
Catherine M. Card+2 more
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Paraxial Mesoderm Is the Major Source of Lymphatic Endothelium [PDF]
Endothelial cells (ECs), which line blood and lymphatic vessels, are generally described to come from the lateral plate mesoderm despite experimental evidence for a broader source of origin, including the paraxial mesoderm (PXM). Current dogma suggests that following specification from mesoderm, local environmental cues establish the distinct molecular
Oliver A. Stone, Didier Y. R. Stainier
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Expression of molecular lymphatic markers in human choroid
The purpose of this study was to research lymphatic outflow tract in the human choroid. Using a light microscopy and immunohistochemistry, structure of the choroid was investigated. We used antibodies against lymphatic endothelial-specific markers Prox-1,
S. R. Nogovitsina
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Imaging long-term fate of intramyocardially implanted mesenchymal stem cells in a porcine myocardial infarction model. [PDF]
The long-term fate of stem cells after intramyocardial delivery is unknown. We used noninvasive, repetitive PET/CT imaging with [(18)F]FEAU to monitor the long-term (up to 5 months) spatial-temporal dynamics of MSCs retrovirally transduced with the ...
Emerson C Perin+34 more
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Convalescent plasma therapy (CPT) has gained significant attention since the onset of the coronavirus disease 2019 (COVID-19) pandemic. However, clinical trials designed to study the efficacy of CPT based on antibody concentrations were inconclusive ...
Nada Amri+8 more
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Direct specification of lymphatic endothelium from mesenchymal progenitors
Abstract During embryogenesis, endothelial cells (ECs) are generally described to arise from a common pool of progenitors termed angioblasts, which diversify through iterative steps of differentiation to form functionally distinct subtypes of ECs.
Irina-Elena Lupu+17 more
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A critical role for lymphatic endothelial heparan sulfate in lymph node metastasis
Background Lymph node metastasis constitutes a key event in tumor progression. The molecular control of this process is poorly understood. Heparan sulfate is a linear polysaccharide consisting of unique sulfate-modified disaccharide repeats that allow ...
Srinivasan R Sathish+6 more
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Mast cell modulation of the vascular and lymphatic endothelium [PDF]
AbstractMast cells (MCs) promote a wide range of localized and systemic inflammatory responses. Their involvement in immediate as well as chronic inflammatory reactions at both local and distal sites points to an extraordinarily powerful immunoregulatory capacity with spatial and temporal versatility.
Soman N. Abraham+3 more
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Purpose. To detect and study the structure of aqueous humor lymphatic outflow pathways in choroid in normotensive patients and patients with primary open-angle glaucoma (POAG).Material and methods.
V. V. Chernykh+7 more
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