Insulin resistance disrupts cell integrity, mitochondrial function, and inflammatory signaling in lymphatic endothelium. [PDF]
Microcirculation, 2018 Lee Y +3 more
europepmc +3 more sources
Dendritic cell interactions with lymphatic endothelium. [PDF]
Lymphat Res Biol, 2013 Afferent lymphatic vessels fulfill essential immune functions by transporting leukocytes and lymph-borne antigen to draining lymph nodes (dLNs). An important cell type migrating through lymphatic vessels are dendritic cells (DCs). DCs reside in peripheral tissues like the skin, where they take up antigen and transport it via the lymphatic vascular ...
Russo E, Nitschké M, Halin C.
europepmc +5 more sources
Homodimerization of the Lymph Vessel Endothelial Receptor LYVE-1 through a Redox-labile Disulfide Is Critical for Hyaluronan Binding in Lymphatic Endothelium. [PDF]
J Biol Chem, 2016 Banerji S +8 more
europepmc +2 more sources
Mast cell modulation of the vascular and lymphatic endothelium [PDF]
Blood, 2011 AbstractMast cells (MCs) promote a wide range of localized and systemic inflammatory responses. Their involvement in immediate as well as chronic inflammatory reactions at both local and distal sites points to an extraordinarily powerful immunoregulatory capacity with spatial and temporal versatility.
Christian A. Kunder +2 more
openalex +4 more sources
Direct specification of lymphatic endothelium from mesenchymal progenitors. [PDF]
Nat Cardiovasc ResAbstract During embryogenesis, endothelial cells (ECs) are generally described to arise from a common pool of progenitors termed angioblasts, which diversify through iterative steps of differentiation to form functionally distinct subtypes of ECs.
Lupu IE +17 more
europepmc +7 more sources
Culturing purifies murine lymph node lymphatic endothelium. [PDF]
Lymphat Res Biol, 2014 Lymph node (LN) lymphatic sinuses transport lymph, cells, and antigens from the periphery through the LN. The lymphatic endothelium lining these sinuses appears to be an important contributor to the lymph node immune response. It has been challenging to obtain sufficient LN lymphatic endothelial cells for investigation of their functions, as they are ...
Jordan-Williams KL, Ruddell A.
europepmc +4 more sources
Frontiers in Physiology, 2021 The lymphatic system is a vascular system comprising modified lymphatic endothelial cells, lymph nodes and other lymphoid organs. The system has diverse, but critical functions in both physiology and pathology, and forms an interface between the blood ...
Zarah B. Tabrizi +4 more
doaj +1 more source
Lymphatic Clearance of Immune Cells in Cardiovascular Disease
Cells, 2021 Recent advances in our understanding of the lymphatic system, its function, development, and role in pathophysiology have changed our views on its importance. Historically thought to be solely involved in the transport of tissue fluid, lipids, and immune
Christophe Ravaud +4 more
doaj +1 more source
Evidence Supporting a Lymphatic Endothelium Origin for Angiomyolipoma, a TSC2(-) Tumor Related to Lymphangioleiomyomatosis. [PDF]
Am J Pathol, 2016 Yue M +6 more
europepmc +3 more sources
Visualization of Endothelial Actin Cytoskeleton in the Mouse Retina [PDF]
, 2012 Angiogenesis requires coordinated changes in cell shape of endothelial cells (ECs), orchestrated by the actin cytoskeleton. The mechanisms that regulate this rearrangement in vivo are poorly understood - largely because of the difficulty to visualize ...
Alessia Fraccaroli +10 more
core +11 more sources