Results 51 to 60 of about 273,293 (311)

Endothelial Dysfunction: From a Pathophysiological Mechanism to a Potential Therapeutic Target

Biomedicines, 2021
The endothelium is considered the largest organ of the body, composed of a monolayer of endothelial cells (ECs) lining the interior surface of blood and lymphatic vessels [...]
Pasquale Ambrosino, Guido Grassi, Mauro Maniscalco   +2 more
doaj   +1 more source

Plasticity of blood- and lymphatic endothelial cells and marker identification. [PDF]

PLoS ONE, 2013
The distinction between lymphatic and blood vessels is biologically fundamental. Here we wanted to rigorously analyze the universal applicability of vascular markers and characteristics of the two widely used vascular model systems human microvascular ...
Johannes Keuschnigg, Sirkku Karinen, Kaisa Auvinen, Heikki Irjala, John-Patrick Mpindi, Olli Kallioniemi, Sampsa Hautaniemi, Sirpa Jalkanen, Marko Salmi   +8 more
doaj   +1 more source

Role of Transcriptional and Epigenetic Regulation in Lymphatic Endothelial Cell Development

Cells, 2022
The lymphatic system is critical for maintaining the homeostasis of lipids and interstitial fluid and regulating the immune cell development and functions.
Hyeonwoo La, Hyunjin Yoo, Young Bin Park, Nguyen Xuan Thang, Chanhyeok Park, Seonho Yoo, Hyeonji Lee, Youngsok Choi, Hyuk Song, Jeong Tae Do, Kwonho Hong   +10 more
doaj   +1 more source

Locally Triggered Release of the Chemokine CCL21 Promotes Dendritic Cell Transmigration across Lymphatic Endothelia

Cell Reports, 2017
Summary: Trafficking cells frequently transmigrate through epithelial and endothelial monolayers. How monolayers cooperate with the penetrating cells to support their transit is poorly understood.
Kari Vaahtomeri, Markus Brown, Robert Hauschild, Ingrid De Vries, Alexander Franz Leithner, Matthias Mehling, Walter Anton Kaufmann, Michael Sixt   +7 more
doaj   +1 more source

Expression of molecular lymphatic markers in human choroid

Acta Biomedica Scientifica, 2016
The purpose of this study was to research lymphatic outflow tract in the human choroid. Using a light microscopy and immunohistochemistry, structure of the choroid was investigated. We used antibodies against lymphatic endothelial-specific markers Prox-1,
S. R. Nogovitsina
doaj   +1 more source

Imaging long-term fate of intramyocardially implanted mesenchymal stem cells in a porcine myocardial infarction model. [PDF]

PLoS ONE, 2011
The long-term fate of stem cells after intramyocardial delivery is unknown. We used noninvasive, repetitive PET/CT imaging with [(18)F]FEAU to monitor the long-term (up to 5 months) spatial-temporal dynamics of MSCs retrovirally transduced with the ...
Emerson C Perin, Mei Tian, Frank C Marini, Guilherme V Silva, Yi Zheng, Fred Baimbridge, Xin Quan, Marlos R Fernandes, Amir Gahremanpour, Daniel Young, Vincenzo Paolillo, Uday Mukhopadhyay, Agatha T Borne, Rajesh Uthamanthil, David Brammer, James Jackson, William K Decker, Amer M Najjar, Michael W Thomas, Andrei Volgin, Brian Rabinovich, Suren Soghomonyan, Hwan-Jeong Jeong, Jesse M Rios, David Steiner, Simon Robinson, Osama Mawlawi, Tinsu Pan, Jason Stafford, Vikas Kundra, Chun Li, Mian M Alauddin, James T Willerson, Elizabeth Shpall, Juri G Gelovani   +34 more
doaj   +1 more source

Use of Early Donated COVID-19 Convalescent Plasma Is Optimal to Preserve the Integrity of Lymphatic Endothelial Cells

Pharmaceuticals, 2022
Convalescent plasma therapy (CPT) has gained significant attention since the onset of the coronavirus disease 2019 (COVID-19) pandemic. However, clinical trials designed to study the efficacy of CPT based on antibody concentrations were inconclusive ...
Nada Amri, Rémi Bégin, Nolwenn Tessier, Laurent Vachon, Louis Villeneuve, Philippe Bégin, Renée Bazin, Lionel Loubaki, Catherine Martel   +8 more
doaj   +1 more source

A critical role for lymphatic endothelial heparan sulfate in lymph node metastasis

Molecular Cancer, 2010
Background Lymph node metastasis constitutes a key event in tumor progression. The molecular control of this process is poorly understood. Heparan sulfate is a linear polysaccharide consisting of unique sulfate-modified disaccharide repeats that allow ...
Srinivasan R Sathish, Johns Scott C, Lawrence Roger, Truty Jadwiga, Yin Xin, Handel Tracy M, Fuster Mark M   +6 more
doaj   +1 more source

THE ELEMENTS OF INTRAOCULAR FLUID LYMPHATIC OUTFLOW PATHWAYS IN CHOROID IN NORM AND IN GLAUCOMA PATIENTS

Офтальмохирургия, 2017
Purpose. To detect and study the structure of aqueous humor lymphatic outflow pathways in choroid in normotensive patients and patients with primary open-angle glaucoma (POAG).Material and methods.
V. V. Chernykh, Yu. I. Borodin, N. P. Bgatova, A. N. Trunov, N. S. Khodjayev, S. R. Nagovitsyna, A. V. Eremina, V. I. Konenkov   +7 more
doaj   +1 more source

Deregulation of HDAC5 by Viral Interferon Regulatory Factor 3 Plays an Essential Role in Kaposi's Sarcoma-Associated Herpesvirus-Induced Lymphangiogenesis. [PDF]

, 2018
Kaposi's sarcoma-associated herpesvirus (KSHV) is the etiologic agent for Kaposi's sarcoma (KS), which is one of the most common HIV-associated neoplasms.
Fan Li, Grace M. Aldrovandi, Hye Ryun Yu, Hye-Ra Lee, Jae U. Jung, Peter Palese, Pinghui Feng, Shou-Jiang Gao, Un Yung Choi, Young-Kwon Hong   +9 more
core   +3 more sources