Results 61 to 70 of about 246,138 (170)

Immersed boundary simulations of cell-cell interactions in whole blood [PDF]

, 2021
We present a new method for the geometric reconstruction of elastic surfaces simulated by the immersed boundary method with the goal of simulating the motion and interactions of cells in whole blood. Our method uses parameter-free radial basis functions for high-order meshless parametric reconstruction of point clouds and the elastic force computations
arxiv   +1 more source

ULTRASTRUCTURAL ORGANIZATION OF THE LYMPHATIC CAPILLARIES IN CONJUNCTIVA AND THE LYMPHATIC CHANNELS IN HUMAN CHOROID

Сибирский научный медицинский журнал, 2019
The aim of this work was a comparative study of the ultrastructural organization of lymphatic structures in the choroid and conjunctiva of the human eye. Material and methods.
S. R. Nogovitsina, N. P. Bgatova, A. V. Eremina, A. N. Trunov, V. V. Chernykh, V. I. Konenkov   +5 more
doaj   +1 more source

Initial afferent lymphatic vessels controlling outbound leukocyte traffic from skin to lymph nodes.

Frontiers in Immunology, 2013
Tissue drains fluid and macromolecules through lymphatic vessels, which are lined by a specialized endothelium that expresses peculiar differentiation proteins, not found in blood vessels (i.e: LYVE-1, Podoplanin, PROX-1 and VEGFR-3).
Ignacio eMelero, Alvaro eTeijeira, Ana eRouzaut   +2 more
doaj   +1 more source

KSHV Induction of Angiogenic and Lymphangiogenic Phenotypes

Frontiers in Microbiology, 2012
Kaposi’s Sarcoma is a highly vascularized tumor supporting large amounts of neo-angiogenesis. The major cell type in KS tumors is the spindle cell, a cell that expresses markers of lymphatic endothelium. KSHV, the etiologic agent of KS, is found in the
Terri A. DiMiao, Michael eLagunoff
doaj   +1 more source

Postnatal Deletion of Podoplanin in Lymphatic Endothelium Results in Blood Filling of the Lymphatic System and Impairs Dendritic Cell Migration to Lymph Nodes

Arteriosclerosis, Thrombosis and Vascular Biology, 2017
Objective— The lymphatic vascular system exerts major physiological functions in the transport of interstitial fluid from peripheral tissues back to the blood circulation and in the trafficking of immune cells to lymph nodes.
R. Bianchi, Erica Russo, Samia B. Bachmann, Steven T. Proulx, Marko Sesartić, Nora Smaadahl, S. Watson, C. Buckley, C. Halin, M. Detmar   +9 more
semanticscholar   +1 more source

PD-L1 signaling selectively regulates T cell lymphatic transendothelial migration

Nature Communications, 2022
The Programmed death-1 (PD-1) and its ligand PD-L1 are critical checkpoints in the regulation of immune responses. Here the authors implicate PD-L1 signalling at lymphatic endothelium in the regulation of transendothelial migration of T cells.
Wenji Piao, Lushen Li, Vikas Saxena, Jegan Iyyathurai, Ram Lakhan, Yigang Zhang, Isadora Tadeval Lape, Christina Paluskievicz, Keli L. Hippen, Young Lee, Emma Silverman, Marina W. Shirkey, Leonardo V. Riella, Bruce R. Blazar, Jonathan S. Bromberg   +14 more
doaj   +1 more source

Targeting local lymphatics to ameliorate heterotopic ossification via FGFR3-BMPR1a pathway

Nature Communications, 2021
Different types of mesenchymal progenitors participate in ectopic bone formation. Here, the authors show Col2+ lineage cells adopt a lymphatic endothelium cell fate, which regulates local inflammatory microenvironment after trauma, thus influencing ...
Dali Zhang, Junlan Huang, Xianding Sun, Hangang Chen, Shuo Huang, Jing Yang, Xiaolan Du, Qiaoyan Tan, Fengtao Luo, Ruobin Zhang, Siru Zhou, Wanling Jiang, Zhenhong Ni, Zuqiang Wang, Min Jin, Meng Xu, Fangfang Li, Liang Chen, Mi Liu, Nan Su, Xiaoqing Luo, Liangjun Yin, Ying Zhu, Jerry Q. Feng, Di Chen, Huabing Qi, Lin Chen, Yangli Xie   +27 more
doaj   +1 more source

Balance of Mechanical Forces Drives Endothelial Gap Formation and May Facilitate Cancer and Immune-Cell Extravasation [PDF]

, 2018
The formation of gaps in the endothelium is a crucial process underlying both cancer and immune cell extravasation, contributing to the functioning of the immune system during infection, the unfavorable development of chronic inflammation and tumor metastasis.
arxiv   +1 more source

LYVE-1 expression in the endothelium of newly formed vessels of carotid atherosclerotic plaque

Анналы клинической и экспериментальной неврологии, 2020
Introduction.The discovery of specific markers of lymphatic endothelium, including LYVE-1, has led to a much better understanding of the structure and function of the lymphatic system.
Anna N. Evdokimenko, Ksenia N. Kulichenkova, Tatiana S. Gulevskaya   +2 more
doaj   +1 more source

Expression of the fms-like tyrosine kinase 4 gene becomes restricted to lymphatic endothelium during development.

Proceedings of the National Academy of Sciences of the United States of America, 1995
We have recently cloned the human fms-like tyrosine kinase 4 gene FLT4, whose protein product is related to two vascular endothelial growth factor receptors FLT1 and KDR/FLK1.
A. Kaipainen, J. Korhonen, T. Mustonen, V. Hinsbergh, G. Fang, D. Dumont, M. Breitman, K. Alitalo   +7 more
semanticscholar   +1 more source