Results 71 to 80 of about 246,138 (170)

Vascular endothelial growth factor receptor-2 promotes the development of the lymphatic vasculature. [PDF]

open access: yesPLoS ONE, 2013
Vascular endothelial growth factor receptor 2 (VEGFR2) is highly expressed by lymphatic endothelial cells and has been shown to stimulate lymphangiogenesis in adult mice. However, the role VEGFR2 serves in the development of the lymphatic vascular system
Michael T Dellinger   +4 more
doaj   +1 more source

Cx47 fine-tunes the handling of serum lipids but is dispensable for lymphatic vascular function. [PDF]

open access: yesPLoS ONE, 2017
Mutations in the gap junction protein connexin47 (Cx47) are associated with lymphedema. However, the role of Cx47 in lymphatic pathophysiology is unknown.
Merlijn J Meens   +13 more
doaj   +1 more source

Loss of Primary Cilia Protein IFT20 Dysregulates Lymphatic Vessel Patterning in Development and Inflammation

open access: yesFrontiers in Cell and Developmental Biology, 2021
Microenvironmental signals produced during development or inflammation stimulate lymphatic endothelial cells to undergo lymphangiogenesis, in which they sprout, proliferate, and migrate to expand the vascular network.
Delayna Paulson   +10 more
doaj   +1 more source

Locally Triggered Release of the Chemokine CCL21 Promotes Dendritic Cell Transmigration across Lymphatic Endothelia

open access: yesCell Reports, 2017
Summary: Trafficking cells frequently transmigrate through epithelial and endothelial monolayers. How monolayers cooperate with the penetrating cells to support their transit is poorly understood.
Kari Vaahtomeri   +7 more
doaj  

A peristaltic soft, wearable robot for compression and massage therapy [PDF]

open access: yesarXiv, 2022
Soft robotics is attractive for wearable applications that require conformal interactions with the human body. Soft wearable robotic garments hold promise for supplying dynamic compression or massage therapies, such as are applied for disorders affecting lymphatic and blood circulation.
arxiv  

Modelling the Lymphatic Metastatic Progression Pathways of OPSCC from Multi-Institutional Datasets [PDF]

open access: yesarXiv, 2023
The elective clinical target volume (CTV-N) in oropharyngeal squamous cell carcinoma (OPSCC) is currently based mostly on the prevalence of lymph node metastases in different lymph node levels (LNLs) for a given primary tumor location. We present a probabilistic model for ipsilateral lymphatic spread that can quantify the microscopic nodal involvement ...
arxiv  

Lymphatic vascularisation and involvement of Lyve-1+ macrophages in the human onchocerca nodule. [PDF]

open access: yesPLoS ONE, 2009
Onchocerciasis, caused by the filarial nematode Onchocerca volvulus, is a parasitic disease leading to debilitating skin disease and blindness, with major economic and social consequences. The pathology of onchocerciasis is principally considered to be a
Tarik Attout   +12 more
doaj   +1 more source

The lymphatic vasculature in lung function and respiratory disease

open access: yesFrontiers in Medicine, 2023
The lymphatic vasculature maintains tissue homeostasis via fluid drainage in the form of lymph and immune surveillance due to migration of leukocytes through the lymphatics to the draining lymph nodes.
Anjali Trivedi   +2 more
doaj   +1 more source

Lymphatic disorders caused by mosaic, activating KRAS variants respond to MEK inhibition

open access: yesJCI Insight, 2023
Central conducting lymphatic anomaly (CCLA) due to congenital maldevelopment of the lymphatics can result in debilitating and life-threatening disease with limited treatment options.
Sarah E. Sheppard   +32 more
doaj   +1 more source

Mechanisms of organogenesis of primary lymphoid follicles [PDF]

open access: yesarXiv, 2006
Primary lymphoid follicles in secondary lymphoid tissue of mammals are the backbone for the formation of follicular dendritic cell networks. These are important for germinal center reactions. In the context of organogenesis molecular requirements for the formation of follicles have been identified.
arxiv  

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