Uncertainty quantification of a three-dimensional in-stent restenosis model with surrogate modelling [PDF]
In-Stent Restenosis is a recurrence of coronary artery narrowing due to vascular injury caused by balloon dilation and stent placement. It may lead to the relapse of angina symptoms or to an acute coronary syndrome. An uncertainty quantification of a model for In-Stent Restenosis with four uncertain parameters (endothelium regeneration time, the ...
arxiv
Lymphatic Programing and Specialization in Hybrid Vessels
Building on a large body of existing blood vascular research, advances in lymphatic research have helped kindle broader investigations into vascular diversity and endothelial plasticity.
John B. Pawlak, Kathleen M. Caron
doaj +1 more source
Histological insight into the hepatic tissue of the Nile monitor (Varanus niloticus) [PDF]
The liver of reptiles is considered an important study model for the interaction between environment and hepatic tissue. Little is known about the histology of the liver of reptiles. The aim of the current study was to elucidate the histological architecture of the liver of the Nile monitor (Varanus niloticus).
arxiv
Pump efficacy in a fluid-structure interaction model of a chain of contracting lymphangions [PDF]
The transport of lymph through the lymphatic vasculature is the mechanism for returning excess interstitial fluid to the circulatory system, and it is essential for fluid homeostasis. Collecting lymphatic vessels comprise a significant portion of the lymphatic vasculature and are divided by valves into contractile segments known as lymphangions ...
arxiv
Corneal endothelium assessment in specular microscopy images with Fuchs' dystrophy via deep regression of signed distance maps [PDF]
Specular microscopy assessment of the human corneal endothelium (CE) in Fuchs' dystrophy is challenging due to the presence of dark image regions called guttae. This paper proposes a UNet-based segmentation approach that requires minimal post-processing and achieves reliable CE morphometric assessment and guttae identification across all degrees of ...
arxiv
BackgroundLymphatic vessels play a pivotal role in fluid drainage and egress of immune cells from the lung. However, examining murine lung lymphatics is hampered by the expression of classical lymph endothelial markers on other cell types, which hinders ...
Sarah Kretschmer+5 more
doaj +1 more source
Misrepair mechanism in the development of atherosclerotic plaques [PDF]
Atherosclerosis is a disease characterized by the development of atherosclerotic plaques (APs) in arterial endothelium. The APs in part of an arterial wall are inhomogeneous on size and on distribution. In order to understand this in-homogeneity, the pathology of APs is analyzed by Misrepair mechanism, a mechanism proposed in our Misrepair-accumulation
arxiv
Endothelial Cell Dysfunction in Viral Hemorrhage and Edema
The endothelium maintains a vascular barrier by controlling platelet and immune cell interactions, capillary tone and interendothelial cell adherence.
Erich Reuter Mackow+2 more
doaj +1 more source
The Role of the Endothelium in HPS Pathogenesis and Potential Therapeutic Approaches
American hantaviruses cause a highly lethal acute pulmonary edema termed hantavirus pulmonary syndrome (HPS). Hantaviruses nonlytically infect endothelial cells and cause dramatic changes in barrier functions of the endothelium without disrupting the ...
Irina Gavrilovskaya+4 more
doaj +1 more source
Spatio-temporal Models of Lymphangiogenesis in Wound Healing [PDF]
Several studies suggest that one possible cause of impaired wound healing is failed or insufficient lymphangiogenesis, that is the formation of new lymphatic capillaries. Although many mathematical models have been developed to describe the formation of blood capillaries (angiogenesis), very few have been proposed for the regeneration of the lymphatic ...
arxiv