The burden of neglected tropical diseases in Ethiopia, and opportunities for integrated control and elimination [PDF]
Background: Neglected tropical diseases (NTDs) are a group of chronic parasitic diseases and related conditions that are the most common diseases among the 2·7 billion people globally living on less than US$2 per day.
A Alemu+103 more
core +2 more sources
Pharmacokinetics, safety, and efficacy of a single co-administered dose of diethylcarbamazine, albendazole and ivermectin in adults with and without Wuchereria bancrofti infection in Cote d\u27Ivoire [PDF]
BackgroundA single co-administered dose of ivermectin (IVM) plus diethylcarbamazine (DEC) plus albendazole (ALB), or triple-drug therapy, was recently found to be more effective for clearing microfilariae (Mf) than standard DEC plus ALB currently used ...
Bjerum, Catherine M+9 more
core +3 more sources
Weight Loss‐Associated Remodeling of Adipose Tissue Immunometabolism
ABSTRACT Obesity is a multifactorial condition characterized by excessive adiposity and systemic chronic low‐grade inflammation. Recent literature reflects a growing appreciation for the complex interplay between metabolism and the immune system in the pathogenesis of obesity‐related health conditions.
Paulo José Basso+5 more
wiley +1 more source
Sensitivity analysis and parameters estimation for the transmission of lymphatic filariasis
Lymphatic filariasis is a neglected tropical disease which poses public health concern and socio-economic challenges in developing and low-income countries.
Mussa A. Stephano+3 more
doaj
Factors associated with the performance and cost-effectiveness of using lymphatic filariasis transmission assessment surveys for monitoring soil-transmitted helminths: a case study in Kenya. [PDF]
Transmission assessment surveys (TAS) for lymphatic filariasis have been proposed as a platform to assess the impact of mass drug administration (MDA) on soil-transmitted helminths (STHs).
Assefa+34 more
core +1 more source
Assessing the reporting quality of published qualitative evidence syntheses in the cochrane library
Abstract Background Over ten years since the first qualitative evidence synthesis (QES) was published in the Cochrane Library, QES and mixed‐methods reviews (MMR) with a qualitative component have become increasingly common and influential in healthcare research and policy development.
Martina Giltenane+12 more
wiley +1 more source
Background In 2016, after 8 years of twice-annual nationwide preventive chemotherapy (PC) administration to school-age children (SAC), the Bangladesh Ministry of Health & Family Welfare (MOHFW) sought improved impact and intervention monitoring data to ...
Stacy L. Davlin+10 more
doaj +1 more source
Escalation of Germinal Center Responses in Chronic Litomosoides sigmodontis Filarial Infection
T follicular helper (TFH) cells provide essential help to B cells in germinal centers (GCs). TFH and GC B cell responses are long‐lasting in draining mediastinal lymph nodes of Litomosoides sigmodontis‐infected BALB/c mice, a rodent model of filarial infection. ABSTRACT T follicular helper (TFH) cells are the primary CD4+ T helper cell subset providing
Teresa Steffen+9 more
wiley +1 more source
Wolbachia, an endosymbiotic bacterium found in most species of filarial parasites, is thought to play a significant role in inducing innate inflammatory responses in lymphatic filariasis
Chantima Porksakorn+3 more
doaj +1 more source
Genital manifestations of tropical diseases [PDF]
Genital symptoms in tropical countries and among returned travellers can arise from a variety of bacterial, protozoal, and helminthic infections which are not usually sexually transmitted.
Richens, J
core +2 more sources