Results 251 to 260 of about 709,350 (366)

CCL2 promotes lymphatic metastasis via activating RhoA and Rac1 pathway and predict prognosis to some extent in tongue cancer. [PDF]

Cancer Biol Ther, 2023
Dong Y, Zhang S, Zhao S, Xuan M, Zhu G, Zhang Z, Guo W.   +6 more
europepmc   +1 more source

ORL@Cu‐MOF Boost Cuproptosis and Suppress Fatty Acid Metabolism for Cancer Lymph Node Metastasis Synergistic Therapy

Advanced Science, EarlyView.
The fabrication of ORL@Cu‐MOF and the mechanism of synergistic therapy by cuproptosis, reprogram fatty acid metabolism and anti‐PD‐1. Abstract Lymph node metastasis (LNM) is one of the significant characteristics of poor prognosis in oral squamous cell carcinoma (OSCC), strongly associated with high mortality rates.
Zi‐Zhan Li, Yi Liu, Kan Zhou, Lei‐Ming Cao, Guang‐Rui Wang, Jinmei Wu, Yi‐Fu Yu, Yao Xiao, Bing Liu, Qiuji Wu, Zhiyong Song, Lin‐Lin Bu   +11 more
wiley   +1 more source

ADAM22 enhances lymphatic metastasis and epithelial-mesenchymal transition in head and neck squamous cell carcinoma cells through integrin signaling. [PDF]

Med Oncol
Yang K, Li Y, Song K, Pan M, Lu T, Wang M, Cheng Z, Hu G, Wen T, Wang M, Chen T.   +10 more
europepmc   +1 more source

HSP90AA1 promotes lymphatic metastasis of hypopharyngeal squamous cell carcinoma by regulating epithelial-mesenchymal transition. [PDF]

Oncol Res, 2023
Tang F, Li Y, Pan M, Wang Z, Lu T, Liu C, Zhou X, Hu G.   +7 more
europepmc   +1 more source

Abnormal β‐Hydroxybutyrylation Modification of ARG1 Drives Reprogramming of Arginine Metabolism to Promote the Progression of Colorectal Cancer

Advanced Science, EarlyView.
Alterations in arginine metabolism and β‐hydroxybutyrylation (Kbhb) modifications play a critical role in tumor progression. This study reveals valuable insights into arginine metabolism reprogramming involving the ARG1‐Kbhb/P300/SLC3A2 signaling axis and uncovers an effective therapy combining BHB with ARG1 inhibitor through conventional enzymatic and
Chuman Lin, Zhiyang Li, Xiaotong Zhu, Wanbing Zhou, Xiansheng Lu, Jiali Zheng, Jie Lin   +6 more
wiley   +1 more source

An HGF-dependent positive feedback loop between bladder cancer cells and fibroblasts mediates lymphangiogenesis and lymphatic metastasis. [PDF]

Cancer Commun (Lond), 2023
Li Y, Zheng H, Luo Y, Lin Y, An M, Kong Y, Zhao Y, Yin Y, Ai L, Huang J, Chen C.   +10 more
europepmc   +1 more source

Effect of enhanced expression of COL8A1 on lymphatic metastasis of hepatocellular carcinoma in mice

, 2012
Zhenhai Ma, Jinhui Ma, Li Jia, Yongfu Zhao   +3 more
openalex   +2 more sources

Age-Related Changes in HAPLN1 Increase Lymphatic Permeability and Affect Routes of Melanoma Metastasis [PDF]

, 2018
Brett L. Ecker, Amanpreet Kaur, Stephen M. Douglass, Marie R. Webster, Filipe V. Almeida, Gloria E. Marino, Andrew J. Sinnamon, M Neuwirth, Gretchen M. Alicea, Abibatou Ndoye, Mitchell E. Fane, Xiaowei Xu, Myung‐Shin Sim, Gary B. Deutsch, Mark B. Faries, Giorgos C. Karakousis, Ashani T. Weeraratna   +16 more
openalex   +1 more source

Clinical Features, Molecular Biology, and the Metastatic Microenvironment in Lung Cancer Brain Metastases: Implications for Treatment Decisions

Advanced Science, EarlyView.
Brain metastases (BM) from lung cancer are aggressive with poor prognosis. This review covers clinical features, diagnosis, early metastasis, and multi‐omics‐elucidated mechanisms, especially the tumor microenvironment of lung cancer with BM. It also discusses preclinical models, signaling pathways, and emerging therapies.
Yixiang Zhu, Danming He, Zan Hou, Mei Lan, Ye Zhang, Qifeng Wang   +5 more
wiley   +1 more source

Analysis of thyroid carcinoma composition and spatial architecture in the progression of dedifferentiation, lymphatic metastasis, and gastric metastasis. [PDF]

J Transl Med
Wang D, Lu R, Yan F, Lin Y, Wang H, Xiong H.   +5 more
europepmc   +1 more source