Results 231 to 240 of about 369,774 (289)

An interpretable machine learning model combining MRI-DKI habitat radiomic features and clinical biomarkers for noninvasive prediction of lymphatic metastasis in rectal cancer: a prospective study. [PDF]

Insights Imaging
Peng L, Li F, Zhang F, Ma F, Zhang X, Zhang X, Chen D, Huang G, Wang L.   +8 more
europepmc   +1 more source

Can Chemoradiotherapy Expand Immune Checkpoint Blockade Responsiveness in Mismatch Repair‐Proficient Rectal Cancer?

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT Immune checkpoint blockade (ICB) has transformed the treatment of mismatch repair‐deficient (dMMR) colorectal cancer but produces no meaningful benefit in advanced mismatch repair‐proficient (pMMR) disease. In the neoadjuvant setting, however, pathological responses have been reported in a subset of pMMR tumors, suggesting that clinical ...
Kimihiro Yamashita, Takeru Matsuda, Junko Mukohyama, Ryohei Sasaki, Yoshihiro Kakeji   +4 more
wiley   +1 more source

Lymphatic Metastasis of Esophageal Squamous Cell Carcinoma: The Role of NRF2 and Therapeutic Strategies. [PDF]

Cancers (Basel)
Li Y, Ladd Z, Xiong Z, Bui-Linh C, Paiboonrungruang C, Subramaniyan B, Li H, Wang H, Balch C, Shersher DD, Spitz F, Chen X.   +11 more
europepmc   +1 more source

Posthumously Diagnosed Myhre Syndrome Presenting With Pleural Remodeling and Endometrial Cancer

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.
ABSTRACT Myhre syndrome (OMIM 139210) is a genetic condition defined by neurodevelopmental disability, characteristic facial features, and multisystem proliferative fibrosis. While various types of lung disease have been reported, pleural remodeling leading to restrictive lung disease has not yet been described.
Jeanette Saffir, Karee Morgan, Karigynn Chaimson, Blake E. Funke, Kim L. Sandler, Melissa Hogan, Thomas Cassini   +6 more
wiley   +1 more source

Single-cell RNA sequencing reveals tumor cell and immune cell variations associated with lymphatic metastasis in papillary thyroid cancer. [PDF]

Endocr Connect
Chen Y, Zhao J, Sun Y, Yang Z, Yang C, Zhu D.   +5 more
europepmc   +1 more source

Establishment and characterization of mouse lymph node fibrosis models

Animal Models and Experimental Medicine, EarlyView.
The design of the entire paper. Schematic illustration of four strategies for establishing mouse lymph node (LN) fibrosis models. The study further compares their fibrotic remodeling patterns and immune alterations. Abstract Background Lymph node (LN) fibrosis occurs in a variety of pathological conditions, including HIV infection, obesity, cancer, and
Yaru Niu, Xu Guan, Jian Ma, Xin Zhang, Yihang Shi, Jinzhu Zhang, Leiqiong Gao, Wei Chen, Xishan Wang   +8 more
wiley   +1 more source

Lateral Pelvic Recurrence in Rectal Cancer Is Not Local Recurrence but Lymphatic Metastasis. [PDF]

J Anus Rectum Colon
Toda S, Inoshita N, Matoba S, Maeda Y, Hiramatsu K, Fukui Y, Hanaoka Y, Ueno M, Kuroyanagi H, Ishikawa F, Ohashi K.   +10 more
europepmc   +1 more source

Zebrafish xenograft models as a fast platform for metastasis diagnosis and cisplatin response of head and neck squamous cell carcinoma

Animal Models and Experimental Medicine, EarlyView.
A zebrafish xenograft model accurately distinguishes metastatic from non‐metastatic HNSCC and recapitulates cisplatin sensitivity/resistance patterns. Using patient‐derived tumors, it predicts individual therapeutic responses, offering a rapid, clinically applicable platform for guiding personalized treatment. Abstract Background Head and neck squamous
Lu Chen, Shu Sun, Yujia Liu, Liehao Jiang, Cuiyun Wu, Ting Liu, Yujiao Zhao, Yuwei Liu, Lu Liu, Qi Wang, Xiaowei Zheng, Ping Huang   +11 more
wiley   +1 more source

Loss of ZC3H12A Expression Is Linked to Higher Mortality Risk and Increased Lymphatic Metastasis in Oral Squamous Cell Carcinoma. [PDF]

In Vivo
Chiang SL, Tsai JJ, Huang YN, Lu JW, Hou SY, Tsai YJ, Lin SH.   +6 more
europepmc   +1 more source

An LCN2-Dependent Positive-Feedback Loop Between Gastric Cancer Cells and Tumor-Associated-Macrophages Mediates Lymphangiogenesis and Lymphatic Metastasis. [PDF]

Adv Sci (Weinh)
Huang Z, Li Y, Qian Y, Ye L, Zhang T, Cheng Y, Wu J, Duan P, Zhang T, Yu Z, Zhao Z, Zhao R, Liang Z, Zhai E, Cai S, Chen J.   +15 more
europepmc   +1 more source