Results 111 to 120 of about 276,175 (315)
Bioengineering tumor‐stroma pancreatic cancer models with potential to emulate the native immunosuppressive tumor microenvironment. Cancer‐on‐a‐bead models exhibited higher relevance for screening immunotherapies and modulating the protumoral PDAC microenvironment. ABSTRACT Pancreatic cancer is notably resistant to treatment, primarily due to its dense
Maria V. Monteiro +4 more
wiley +1 more source
The influence of season, photoperiod, and pineal melatonin on immune function. [PDF]
In addition to the well-documented seasonal cycles of mating and birth, there are also significant seasonal cycles of illness and death among many animal populations.
Demas, G +3 more
core +1 more source
Lymphatic System and Fistulas—Radiological Imaging Primer [PDF]
Christof M. Sommer, Claus C. Pieper
openalex +1 more source
A novel method that combines 3D printing and organ‐on‐chip technology enables the creation of hollow channels lined with endothelial cells through a fibroblast‐populated connective tissue matrix. The model supports stable metabolic culture conditions, angiogenic sprouting, and immune cell migration, thereby demonstrating an easy and versatile method to
Jonas Jäger +7 more
wiley +1 more source
The cerebral lymphatic system plays a critical role in central nervous system (CNS) homeostasis through fluid regulation, toxin clearance, and immune modulation.
Mark Jessup +9 more
doaj +1 more source
Deciphering the Pathobiological Impairment Mechanisms of the Lymphatic System during Secondary Lymphedema Progression [PDF]
Epameinondas Gousopoulos
openalex +1 more source
A Human‐Based Skin‐Lymphoreticular Model‐on‐Chip to Emulate Inflammatory Skin Conditions
A human‐based lymphoreticular (LR) model was developed through guided self‐assembly and integrated in a skin‐lymphoreticular co‐culture in a microfluidic organ‐on‐chip to mimic interactions between skin and its draining lymph nodes. The human‐based skin‐lymphoreticular model resembles a minimally functional unit that allows to study interactions ...
Zheng Tan +3 more
wiley +1 more source
Modern biotherapy has been in use for some 30 years. The first types of biotherapy were nonspecific stimulators of the immune response, but advances in genetic engineering are allowing the mass production of pure biological products which are now being ...
Gallucci, Betty Bierut +1 more
core +1 more source
Microphysiological Systems of Lymphatics and Immune Organs
This review surveys recent progress in engineering lymphatic microenvironments and immune organoids within microphysiological systems, emphasizing innovative strategies to recreate the biochemical and biophysical complexity of native lymphatic tissues.
Ishita Jain +2 more
wiley +1 more source

