Functional Synovium‐Based 3D Models in the Context of Human Disease and Inflammation
The synovium is key to joint function but is often affected by diseases like rheumatoid arthritis. Finding better treatments is challenging because current lab models do not fully mimic real tissues. New 3D technologies, like bioprinting, offer better methods to study these diseases, improve drug testing, and develop personalized treatments, bringing ...
Amelia Heslington+3 more
wiley +1 more source
Sinusoidal and lymphatic vessel growth is controlled by reciprocal VEGF-C-CDH5 inhibition. [PDF]
Sung DC+16 more
europepmc +1 more source
Lymphatic vessel density in pulmonary adenocarcinoma immunohistochemically evaluated with anti‐podoplanin or anti‐D2‐40 antibody is correlated with lymphatic invasion or lymph node metastases [PDF]
Yoshin Adachi+9 more
openalex +1 more source
Abstract Plutonium was discovered and first synthesized in the early 1940's. Several isotopes of plutonium are used in nuclear technologies, 238Pu for heat generation and 239Pu for energy production and weapons. Both isotopes emit alpha particles, which pose a significant radiation hazard when incorporated into the body.
Scott C. Miller
wiley +1 more source
Progress and challenges of mRNA vaccines
As the third‐generation nucleic acid vaccine, the Messenger RNA (mRNA) vaccine stimulates a specific immune response by introducing mRNA expressing the target antigen into the body through a specific delivery system and expressing the corresponding protein.
Liangru Lin+3 more
wiley +1 more source
A 3D Human Lymphatic Vessel-on-Chip Reveals the Roles of Interstitial Flow and VEGF-A/C for Lymphatic Sprouting and Discontinuous Junction Formation. [PDF]
Ilan IS, Yslas AR, Peng Y, Lu R, Lee E.
europepmc +1 more source
Lymphatic vessels assessment in feline mammary tumours [PDF]
Giuseppe Sarli+5 more
openalex +1 more source
Association of Synovial Innate Immune Exhaustion With Worse Pain in Knee Osteoarthritis
Objective Uncontrolled pain remains a major clinical challenge in the management of knee osteoarthritis (OA), the most common disabling joint disease. Worse pain is associated with synovial innate immune cell infiltration (synovitis), but the role of innate immune‐regulatory cells in pain is unknown. Our objective was to identify synovial innate immune
Holly T. Philpott+14 more
wiley +1 more source
Long-term physical exercise facilitates putative glymphatic and meningeal lymphatic vessel flow in humans. [PDF]
Yoo RE+9 more
europepmc +1 more source