FOXC1 and FOXC2 Ablation Causes Abnormal Valvular Endothelial Cell Junctions and Lymphatic Vessel Formation in Myxomatous Mitral Valve Degeneration. [PDF]
Tan C +6 more
europepmc +1 more source
ABSTRACT This study developed a non‐invasive model using PIVKA‐II and MRI features to predict microvascular invasion in hepatocellular carcinoma, providing a reliable tool for early risk assessment and personalized treatment planning. The study included 98 patients with pathologically confirmed HCC (Child‐Pugh A, BCLC stage A), comprising 43 MVI ...
Di Gao, Rui‐Qi Jin, Hong‐Wei Wang
wiley +1 more source
Lymphatic vessel transit seeds cytotoxic resident memory T cells in skin draining lymph nodes. [PDF]
Heim TA +6 more
europepmc +1 more source
KAT2A Promotes the Progression of Renal Cell Carcinoma by Regulating the Succinylation of SERPINE2
ABSTRACT Epithelial‐mesenchymal transition (EMT) and angiogenesis are critical drivers of renal cell carcinoma (RCC) progression, yet their upstream regulatory mechanisms remain incompletely understood. This study aimed to investigate the role of KAT2A in RCC and elucidate the underlying molecular mechanism by which it promotes tumor progression.
Chang‐Cheng Liu, Xue‐Dong Li
wiley +1 more source
Sustained meningeal lymphatic vessel atrophy or expansion does not alter Alzheimer's disease-related amyloid pathology. [PDF]
Antila S +26 more
europepmc +1 more source
ABSTRACT Sepsis‐induced acute lung injury (ALI) remains challenging to treat, with conventional anti‐inflammatory therapies offering limited efficacy. The lymphatic system is crucial for removing edema and inflammatory mediators, and its impairment can exacerbate lung injury.
He Wang +4 more
wiley +1 more source
Increased Microvascular Filtration and Vascular Endothelial Growth Factor-D associated with Changed Lymphatic Vessel Morphology in Breast Cancer Treated Patients. [PDF]
Johannessen AL +5 more
europepmc +1 more source
ABSTRACT Circadian rhythms orchestrate cardiovascular physiology by regulating immune and inflammatory pathways. Disruption of these rhythms profoundly alters vascular homeostasis, thereby promoting the onset and progression of cardiovascular diseases (CVD).
Tian Zhang +22 more
wiley +1 more source
Meningeal lymphatic vessel crosstalk with central nervous system immune cells in aging and neurodegenerative diseases. [PDF]
Gao M +7 more
europepmc +1 more source
This review summarizes the immuno‐inflammatory mechanisms driving the pathogenesis of osteoarthritis (OA), extending beyond the traditional view of OA as a purely degenerative disease to incorporate immune cell infiltration, inflammatory factor release, and the formation of a chronic low‐grade inflammatory microenvironment.
Qingqiang Lei +9 more
wiley +1 more source

