Results 221 to 230 of about 403,412 (304)

Genetic Mutations in Recurrent/Metastatic Papillary Thyroid Carcinoma

The Laryngoscope, EarlyView.
We investigated the mutational landscape and prognostic implications of recurrent/metastatic papillary thyroid carcinoma using nationwide C‐CAT data from 348 patients. CDKN2A, KMT2D, and concurrent TERT/BRAF mutations were independently associated with poorer overall survival, highlighting the potential prognostic value of comprehensive genomic ...
Hiromi Nagano, Satoshi Kiyama, Takayuki Kyutoku, Masaru Yamashita   +3 more
wiley   +1 more source

Spatiospectral Photoacoustic Microscopy With Gain‐Switched Ti:Sapphire Laser for High‐Accuracy Molecular Dynamics Imaging

Laser &Photonics Reviews, EarlyView.
Spatiospectral photoacoustic microscopy is enabled by stable, wavelength‐tunable dual‐pulse excitation from a gain‐switched Ti:sapphire laser. Intrinsically synchronized 532‐nm and NIR‐I pulses provide single‐scan, co‐registered mapping of oxygen saturation and indocyanine green dynamics in vivo.
Yong‐Jae Lee, Thanh Dat Le, Dong Hoon Song, Jin Hee Im, Seong‐Young Kwon, Tae Young Jeong, Jung‐Joon Min, Changho Lee, Tae Joong Eom   +8 more
wiley   +1 more source

Long-term physical exercise facilitates putative glymphatic and meningeal lymphatic vessel flow in humans. [PDF]

Nat Commun
Yoo RE, Kim JH, Moon HY, Park JY, Cheon S, Shin HS, Han D, Kim Y, Park SH, Choi SH.   +9 more
europepmc   +1 more source

Osteoarthritis: An Immuno‐Inflammatory Disease‐Mechanisms of Immune Cell Dysregulation and Potential Therapeutic Strategies

Med Research, EarlyView.
This review summarizes the immuno‐inflammatory mechanisms driving the pathogenesis of osteoarthritis (OA), extending beyond the traditional view of OA as a purely degenerative disease to incorporate immune cell infiltration, inflammatory factor release, and the formation of a chronic low‐grade inflammatory microenvironment.
Qingqiang Lei, Xiaoxian Lou, Xu Su, Shubao Liu, Yanli Tong, Jie Chen, Xuerui Chen, Wenjun Mao, Hui Yu, Liangbin Lin   +9 more
wiley   +1 more source

Comparison of the Quality of Lymphatic Vessel Images Obtained Using Two Photoacoustic Imaging Systems. [PDF]

Plast Reconstr Surg Glob Open
Suzuki Y, Kajita H, Otaki M, Watanabe S, Okabe K, Sakuma H, Takatsume Y, Asano Y, Soga S, Imanishi N, Sato I, Jinzaki M, Kishi K.   +12 more
europepmc   +1 more source

Organoid Coculture Models for Cancer Research and Immunotherapy

Med Research, EarlyView.
This review summarizes organoid coculture platforms, including submerged Matrigel culture, air–liquid interface, microfluidic/organoid‐on‐a‐chip, and 3D bioprinting, for reconstructing the tumor microenvironment to study tumor–stroma/immune crosstalk, evaluate immunotherapies, and enable drug screening.
Zhuo Yang, Huihui Yang, Guangxin Li, Guobang Liu, Zhulan Chen, Wenzhi Tian, Meiyang Huang, Xiaoling Liu, Yongsheng Zhao, Dong Chen   +9 more
wiley   +1 more source

Redefining CHI3L1: Therapeutic Opportunities at the Crossroads of Immune Suppression and Disease Progression

Medicinal Research Reviews, EarlyView.
ABSTRACT Chitinase‐3‐like‐1 (CHI3L1, also known as YKL‐40) has been recognized as a biomarker of inflammation and tissue remodeling and has now emerged as a pseudoenzymatic immune checkpoint. Recent structural, immunological, and translational studies redefine it as an active regulator of immune suppression rather than a passive disease marker. Despite
Kirti Upmanyu, Saurabh Upadhyay, Moustafa T. Gabr   +2 more
wiley   +1 more source

Lymphatic vessel network injury reduces local tumor control despite preservation of the tumor-draining lymph node. [PDF]

Sci Rep
Liebman LN, Shen Y, Buchwald ZS, Nepiyushchikh Z, Qi Z, García AJ, Dixon JB.   +6 more
europepmc   +1 more source

Pink Polypoid Papulo‐Vesicles on Labia Majora

JEADV Clinical Practice, EarlyView.
Maria Chiara Mercuri, Michela Tabanelli, Silvia Zago, Diego Abbenante   +3 more
wiley   +1 more source

Recent Advances in Cryogel Applications for Musculoskeletal Regeneration

Medicinal Research Reviews, EarlyView.
ABSTRACT Hydrogels have been widely used in tissue engineering due to their high‐water content and biocompatibility, yet their densely cross‐linked microstructure inherently limits cell infiltration, mass transport, and mechanical support. Cryogels, formed through partial freezing and crosslinking under subzero conditions, provide unique 3D macroporous
Dohee Kim, Shinwon Kang, Hyejin Jo, Inseon Kim, Seunghun S. Lee   +4 more
wiley   +1 more source