Results 31 to 40 of about 1,026,018 (392)
Blood and Lymphatic Vessel Formation [PDF]
Cold Spring Harbor Perspectives in Biology, 2015 Blood and lymphatic vessels deliver oxygen and nutrients, remove waste and CO2, and regulate interstitial pressure in tissues and organs. These vessels begin life early in embryogenesis using transcription factors and signaling pathways that regulate differentiation, morphogenesis, and proliferation.
Victoria L, Bautch, Kathleen M, Caron
openaire +2 more sources
EBioMedicine, 2021 Background: In head and neck cancer, intratumour lymphatic density and tumour lymphangiogenesis have been correlated with lymphatic metastasis, making lymphangiogenesis a promising therapeutic target.
Karina M. Lugo-Cintrón +8 more
doaj +1 more source
Objective assessment of blood and lymphatic vessel invasion and association with macrophage infiltration in cutaneous melanoma [PDF]
, 2011 The aims of this study were to investigate the role of vascular invasion (blood and lymphatic), vessel density and the presence of tumour-associated macrophages as prognostic markers in 202 cutaneous melanoma patients.
Cook, Martin +12 more
core +3 more sources
Chronic high-fat diet impairs collecting lymphatic vessel function in mice.
PLoS ONE, 2014 Lymphatic vessels play an essential role in intestinal lipid uptake, and impairment of lymphatic vessel function leads to enhanced adipose tissue accumulation in patients with lymphedema and in genetic mouse models of lymphatic dysfunction.
Katrin S Blum +7 more
doaj +1 more source
High relative density of lymphatic vessels predicts poor survival in tongue squamous cell carcinoma [PDF]
, 2016 Tongue cancer has a poor prognosis due to its early metastasis via lymphatic vessels. The present study aimed at evaluating lymphatic vessel density, relative density of lymphatic vessel, and diameter of lymphatic vessels and its predictive role in ...
Huhtala, Heini +8 more
core +1 more source
A Tumor‐on‐a‐Chip System with Bioprinted Blood and Lymphatic Vessel Pair
Advanced Functional Materials, 2019 Current in vitro antitumor drug screening strategies insufficiently mimic biological systems. They tend to lack true perfusion and draining microcirculation systems, which may post significant limitations in explicitly reproducing the transport kinetics ...
Xia Cao +9 more
semanticscholar +1 more source
Three-Dimensional In Vitro Lymphangiogenesis Model in Tumor Microenvironment
Frontiers in Bioengineering and Biotechnology, 2021 Lymphangiogenesis is a stage of new lymphatic vessel formation in development and pathology, such as inflammation and tumor metastasis. Physiologically relevant models of lymphatic vessels have been in demand because studies on lymphatic vessels are ...
Youngkyu Cho +9 more
doaj +1 more source
Lymphatic Vessel Network Structure and Physiology.
Comprehensive Physiology, 2018 The lymphatic system is comprised of a network of vessels interrelated with lymphoid tissue, which has the holistic function to maintain the local physiologic environment for every cell in all tissues of the body.
J. Breslin +5 more
semanticscholar +1 more source
Microfluidic System to Analyze the Effects of Interleukin 6 on Lymphatic Breast Cancer Metastasis
Frontiers in Bioengineering and Biotechnology, 2021 Metastasis is the primary cause of a large number of cancer-associated deaths. By portraying the precise environment of the metastasis process in vitro, the microfluidic system provides useful insights on the mechanisms underlying cancer cell migration ...
Hyeon-Yeol Cho +5 more
doaj +1 more source
MT1-MMP sheds LYVE-1 on lymphatic endothelial cells and suppresses VEGF-C production to inhibit lymphangiogenesis [PDF]
, 2016 Lymphangiogensis is involved in various pathological conditions, such as arthritis and cancer metastasis. Although many factors have been identified to stimulate lymphatic vessel growth, little is known about lymphangiogenesis inhibitors.
Cao, R +5 more
core +1 more source