Results 31 to 40 of about 923,689 (313)
Tumor-Associated Lymphatic Vessel Features and Immunomodulatory Functions
Frontiers in Immunology, 2019 The lymphatic system comprises a network of lymphoid tissues and vessels that drains the extracellular compartment of most tissues. During tumor development, lymphatic endothelial cells (LECs) substantially expand in response to VEGFR-3 engagement by ...
L. Garnier, A. Gkountidi, S. Hugues
semanticscholar +1 more source
Microanatomical organization of hepatic venous lymphatic system in humans
PLoS ONE, 2023 Lymphatic fluid drains from the liver via the periportal lymphatic, hepatic venous lymphatic, and superficial lymphatic systems. We performed a postmortem study to clarify the three-dimensional structure and flow dynamics of the human hepatic venous ...
Kotaro Umemura +11 more
doaj +2 more sources
Impaired meningeal lymphatic vessel development worsens stroke outcome
Journal of Cerebral Blood Flow and Metabolism, 2019 The discovery of meningeal lymphatic vessels (LVs) has sparked interest in identifying their role in diseases of the central nervous system. Similar to peripheral LVs, meningeal LVs depend on vascular endothelial growth factor receptor-3 (VEGFR3 ...
Pavel Yanev +8 more
semanticscholar +1 more source
Journal of Experimental & Clinical Cancer Research, 2009 Background To investigate the role of vascular endothelial growth factors (VEGF)-C/D and their receptor Flt-4 in the lymphatic metastasis of early-stage invasive cervical carcinoma.
Zhang Renhua +3 more
doaj +1 more source
Lymphatic Vessels and Their Surroundings: How Local Physical Factors Affect Lymph Flow
Biology, 2020 Lymphatic vessels drain and propel lymph by exploiting external forces that surrounding tissues exert upon vessel walls (extrinsic mechanism) and by using active, rhythmic contractions of lymphatic muscle cells embedded in the vessel wall of collecting ...
Eleonora Solari +3 more
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Solute Transport across the Lymphatic Vasculature in a Soft Skin Tissue
Biology, 2023 Convective transport of drug solutes in biological tissues is regulated by the interstitial fluid pressure, which plays a crucial role in drug absorption into the lymphatic system through the subcutaneous (SC) injection.
Dingding Han +3 more
doaj +1 more source
Nature Communications, 2018 Tissue and vessel wall stiffening alters endothelial cell properties and contributes to vascular dysfunction. However, whether extracellular matrix (ECM) stiffness impacts vascular development is not known.
Maike Frye +13 more
semanticscholar +1 more source
Microfluidic System to Analyze the Effects of Interleukin 6 on Lymphatic Breast Cancer Metastasis
Frontiers in Bioengineering and Biotechnology, 2021 Metastasis is the primary cause of a large number of cancer-associated deaths. By portraying the precise environment of the metastasis process in vitro, the microfluidic system provides useful insights on the mechanisms underlying cancer cell migration ...
Hyeon-Yeol Cho +5 more
doaj +1 more source
Oncoimmunology, 2018 Increased density of tumor-associated lymphatic vessels correlates with poor patient survival in melanoma and other cancers, yet lymphatic drainage is essential for initiating an immune response.
N. Bordry +21 more
semanticscholar +1 more source
BMC Cancer, 2009 Background Cervical cancer is the most common malignant gynecological cancer, and lymphatic metastasis can occur in the early stage of tumor growth. Lymphatic vessel endothelial hyaluronan receptor-1 (LYVE-1), a marker for lymphatic endothelium, provides
Yu Hao, Zhang Shi-qian, Zhang Lin-lin
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