Results 31 to 40 of about 1,011,532 (393)
Chronic high-fat diet impairs collecting lymphatic vessel function in mice.
PLoS ONE, 2014 Lymphatic vessels play an essential role in intestinal lipid uptake, and impairment of lymphatic vessel function leads to enhanced adipose tissue accumulation in patients with lymphedema and in genetic mouse models of lymphatic dysfunction.
Katrin S Blum +7 more
doaj +1 more source
A Tumor‐on‐a‐Chip System with Bioprinted Blood and Lymphatic Vessel Pair
Advanced Functional Materials, 2019 Current in vitro antitumor drug screening strategies insufficiently mimic biological systems. They tend to lack true perfusion and draining microcirculation systems, which may post significant limitations in explicitly reproducing the transport kinetics ...
Xia Cao +9 more
semanticscholar +1 more source
Lymphangiography to treat postoperative lymphatic leakage: a technical review. [PDF]
, 2014 In addition to imaging the lymphatics and detecting various types of lymphatic leakage, lymphangiography is a therapeutic option for patients with chylothorax, chylous ascites, and lymphatic fistula.
Kim, Soo Hwan +5 more
core +1 more source
Lymphatic Vessel Network Structure and Physiology.
Comprehensive Physiology, 2018 The lymphatic system is comprised of a network of vessels interrelated with lymphoid tissue, which has the holistic function to maintain the local physiologic environment for every cell in all tissues of the body.
J. Breslin +5 more
semanticscholar +1 more source
Three-Dimensional In Vitro Lymphangiogenesis Model in Tumor Microenvironment
Frontiers in Bioengineering and Biotechnology, 2021 Lymphangiogenesis is a stage of new lymphatic vessel formation in development and pathology, such as inflammation and tumor metastasis. Physiologically relevant models of lymphatic vessels have been in demand because studies on lymphatic vessels are ...
Youngkyu Cho +9 more
doaj +1 more source
Tumor-Associated Lymphatic Vessel Features and Immunomodulatory Functions
Frontiers in Immunology, 2019 The lymphatic system comprises a network of lymphoid tissues and vessels that drains the extracellular compartment of most tissues. During tumor development, lymphatic endothelial cells (LECs) substantially expand in response to VEGFR-3 engagement by ...
L. Garnier, A. Gkountidi, S. Hugues
semanticscholar +1 more source
MT1-MMP sheds LYVE-1 on lymphatic endothelial cells and suppresses VEGF-C production to inhibit lymphangiogenesis [PDF]
, 2016 Lymphangiogensis is involved in various pathological conditions, such as arthritis and cancer metastasis. Although many factors have been identified to stimulate lymphatic vessel growth, little is known about lymphangiogenesis inhibitors.
Cao, R +5 more
core +1 more source
Impaired meningeal lymphatic vessel development worsens stroke outcome
Journal of Cerebral Blood Flow and Metabolism, 2019 The discovery of meningeal lymphatic vessels (LVs) has sparked interest in identifying their role in diseases of the central nervous system. Similar to peripheral LVs, meningeal LVs depend on vascular endothelial growth factor receptor-3 (VEGFR3 ...
Pavel Yanev +8 more
semanticscholar +1 more source
Microfluidic System to Analyze the Effects of Interleukin 6 on Lymphatic Breast Cancer Metastasis
Frontiers in Bioengineering and Biotechnology, 2021 Metastasis is the primary cause of a large number of cancer-associated deaths. By portraying the precise environment of the metastasis process in vitro, the microfluidic system provides useful insights on the mechanisms underlying cancer cell migration ...
Hyeon-Yeol Cho +5 more
doaj +1 more source
Nature Communications, 2018 Tissue and vessel wall stiffening alters endothelial cell properties and contributes to vascular dysfunction. However, whether extracellular matrix (ECM) stiffness impacts vascular development is not known.
Maike Frye +13 more
semanticscholar +1 more source