Results 81 to 90 of about 87,743 (301)

Anatomical information science [PDF]

, 2005
The Foundational Model of Anatomy (FMA) is a map of the human body. Like maps of other sorts – including the map-like representations we find in familiar anatomical atlases – it is a representation of a certain portion of spatial reality as it exists at ...
Kumar, Anand, Mejino, Jose L V, Rosse, Cornelius, Schultz, Stefan, Smith, Barry   +4 more
core   +2 more sources

Decellularized Extracellular Matrix (dECM) in Tendon Regeneration: A Comprehensive Review

Advanced Healthcare Materials, EarlyView.
Decellularized Extracellular Matrix (dECM) offers a promising solution by replicating the native tendon microenvironment and promoting regeneration. This review highlights advances in the decellularization methods, as well as their integration with emerging technologies and translational progress in tendon tissue engineering.
Kumaresan Sakthiabirami, Yeonwoo Park, Seong Kyeong Jo, Min Hee Kim, Jae Hwang Song   +4 more
wiley   +1 more source

Mechanical feedback mechanisms in a multiscale sliding filament model of lymphatic muscle pumping

Applications in Engineering Science
The lymphatic system maintains bodily fluid balance by returning interstitial fluid to the venous system. Flow can occur through a combination of extrinsic pumping, due to forces from surrounding tissues, and intrinsic pumping involving contractions of ...
Peter Y. Xie, Christopher J. Morris, Christopher D. Bertram, Michael J. Davis, Samira Jamalian, Mohammad Jafarnejad, David C. Zawieja, James E. Moore, Jr   +7 more
doaj   +1 more source

Prognostic significance of lymphangiogenesis in pharyngolaryngeal carcinoma patients

BMC Cancer, 2010
Background Lymphatic vessel spread is considered a major route for head and neck squamous cell carcinoma metastasis. Formation of new lymphatic vessels could facilitate the process, raising the malignant potential of these tumours.
Garcia-Carracedo Darío, Rodrigo Juan, Astudillo Aurora, Nieto Carlos, Gonzalez Maria   +4 more
doaj   +1 more source

Advances in Bioprinting to Model Immune‐Mediated Skin Diseases

Advanced Healthcare Materials, EarlyView.
This review explores how 3D bioprinting drives innovation in developing in vitro skin models that mimic immune‐mediated diseases. It highlights current technologies, key applications in studying skin pathologies, and emerging challenges. The review points toward future opportunities for improving disease modeling and advancing therapeutic and cosmetic ...
Andrea Ulloa‐Fernández, Marica Markovic, Julia Fernández‐Pérez, Georg Stary, Aleksandr Ovsianikov   +4 more
wiley   +1 more source

Microneedle Technology in Psoriasis Management: Mechanistic Insights, Technological Innovation, Clinical Progress, and Challenges

Advanced Healthcare Materials, EarlyView.
This review explores the evolving role of microneedle systems in psoriasis management, highlighting their potential for enhanced drug delivery, diagnosis, and disease monitoring. It also discusses unmet clinical needs for psoriasis management and technical challenges, while outlining strategic directions to advance microneedle integration into routine ...
Fatma Moawad, Yasmine Ruel, Roxane Pouliot, Davide Brambilla   +3 more
wiley   +1 more source

VIPAR, a quantitative approach to 3D histopathology applied to lymphatic malformations. [PDF]

, 2017
BACKGROUND: Lack of investigatory and diagnostic tools has been a major contributing factor to the failure to mechanistically understand lymphedema and other lymphatic disorders in order to develop effective drug and surgical therapies.
Butz, S, Dierkes, C, Drees, D, Goerge, T, Gordon, K, Hinrichs, K, Hägerling, R, Jiang, X, Kiefer, F, Mansour, S, Martin-Almedina, S, Mortimer, PS, Ostergaard, P, Scherzinger, A, Schäfers, M, Vestweber, D   +15 more
core   +1 more source

siRNA Delivery via Cross‐Linked Gelatin Microparticles Enables Targeted Modulation of Osteogenic‐Vascular Cross‐Talk: An Advanced Human 3D in Vitro Test System for Therapeutic siRNA

Advanced Healthcare Materials, EarlyView.
Osteogenic‐angiogenic cross‐talk is a vital prerequisite for vascularized bone regeneration. In this study, we investigated the effects of siRNA‐mediated silencing of two inhibitory proteins, Chordin and WWP‐1, via CaP‐NP‐loaded gelatin microparticles in osteogenically differentiated microtissues.
Franziska Mitrach, Jonas Kubat, Stefan Simm, Alexandra H. Springwald, Burak Demir, Anton Liebezeit, Michael C. Hacker, Michaela Schulz‐Siegmund   +7 more
wiley   +1 more source

Lattice Structures for Bone Replacement: The Intersection of Bone Biomechanics, Lattice Design, and Additive Manufacturing

Advanced Materials Technologies, EarlyView.
This review outlines how understanding bone's biology, hierarchical architecture, and mechanical anisotropy informs the design of lattice structures that replicate bone morphology and mechanical behavior. Additive manufacturing enables the fabrication of orthopedic implants that incorporate such structures using a range of engineering materials ...
Stylianos Kechagias, Maxwell J. Munford, Frederik C.H. Masure, Richard J. van Arkel, Reece N Oosterbeek   +4 more
wiley   +1 more source

New Microcannulation Technique for Imaging Contrast and Drug Delivery via the Lymphatics

Plastic and Reconstructive Surgery, Global Open
Summary:. A technique for drug delivery using the lymphatics was introduced and tested in animals half a century ago, but was never trialed in human subjects. Recently, surgical manipulation of lymphatic vessels for lymphedema treatment has attracted the
Hiroo Suami, MD, PhD
doaj   +1 more source