Results 151 to 160 of about 1,001,687 (372)

Engineered Probiotics Mitigate Gut Barrier Dysfunction Induced by Nanoplastics

Advanced Science, EarlyView.
Intestinal barrier stability is vital for gut health. Plastic polyethylene terephthalate (PET) disrupts this barrier, causing inflammation and infections. This study encodes transforming growth factor‐β into EcN and modifies its surface with pH‐responsive polymer (EcNT@L), creating an oral drug delivery system to repair nano PET‐induced intestinal ...
Wenxin Chen, Qiyan Guo, Hong Li, Xue Chi, Xiang Ma, Yanqiong Tang, Quanfeng Liang, Zhu Liu, Yong Liu, Juanjuan Li   +9 more
wiley   +1 more source

Global weak solutions to a fractional Cahn-Hilliard cross-diffusion system in lymphangiogenesis [PDF]

arXiv
A spectral-fractional Cahn-Hilliard cross-diffusion system, which describes the pre-patterning of lymphatic vessel morphology in collagen gels, is studied. The model consists of two higher-order quasilinear parabolic equations and describes the evolution of the fiber phase volume fraction and the solute concentration.
arxiv  

Camouflaged Nanozymes with Oxidation‐Promoting Activities Triggering Ferroptosis for Radio‐Immunotherapy

Advanced Science, EarlyView.
This study develops a cancer cell membrane‐coated nanozyme that enhances radiotherapy and reshapes the immunosuppressive microenvironment by generating oxygen in situ and disrupting tumor antioxidant defenses, offering a new strategy for breast cancer radioimmunotherapy.
Kun Qiao, Yongbiao Huang, Shipeng Ning, Meng Lyu, Jieqiong Xie, Shiyuan Zhang, Xiuxin Lu, Yuan Yu, Wei Jiang, Bo Liu, Kelong Fan, Tong Liu   +11 more
wiley   +1 more source

MLV$^2$-Net: Rater-Based Majority-Label Voting for Consistent Meningeal Lymphatic Vessel Segmentation [PDF]

arXiv
Meningeal lymphatic vessels (MLVs) are responsible for the drainage of waste products from the human brain. An impairment in their functionality has been associated with aging as well as brain disorders like multiple sclerosis and Alzheimer's disease. However, MLVs have only recently been described for the first time in magnetic resonance imaging (MRI),
arxiv  

β‐adrenoceptor‐mediated facilitation of [³H]‐noradrenaline release from the intramural nerves of bovine mesenteric lymphatic vessels [PDF]

, 1989
James M. Allen, John G. McCarron, Noel G. McHale, K. D. Thornbury   +3 more
openalex   +1 more source

Comparison of the Quality of Lymphatic Vessel Images Obtained Using Two Photoacoustic Imaging Systems

Plastic and Reconstructive Surgery, Global Open
Summary:. Photoacoustic imaging (PAI) can evaluate lymphatic vessels with a high resolution (0.2 mm) compared with other methods. LUB0, a new PAI device that is smaller than the PAI-05 used since 2020 (both from Luxonus, Inc.), has been introduced.
Yushi Suzuki, MD, PhD, Hiroki Kajita, MD, PhD, Marika Otaki, MD, Shiho Watanabe, MD, Keisuke Okabe, MD, PhD, Hisashi Sakuma, MD, Yoshifumi Takatsume, PhD, Yuta Asano, PhD, Shigeyoshi Soga, MD, PhD, Nobuaki Imanishi, MD, PhD, Imari Sato, PhD, Masahiro Jinzaki, MD, PhD, Kazuo Kishi, MD, PhD   +12 more
doaj   +1 more source

Locoregional Immune Checkpoint Blockade and Remodeling of Lymph Nodes by Engineered Dendritic Cell‐Derived Exosomes for Suppressing Tumor Progression and Metastasis

Advanced Science, EarlyView.
The study develops engineered exosomes (EmDEX@GA) for locoregional immunomodulation of tumor‐draining lymph node (TDLN). EmDEX@GA can actively target to TDLN and remodel its immunosuppressive microenvironment through the synergistic effects of PD‐1/PD‐L1 blockade and STING pathway activation, subsequently enhance anti‐tumor immunity and suppress tumor ...
Yizhen Wang, Xiaomin Guo, Jingya Qin, Yifan Xue, Peng Zhang, Yadong Liu, Moyang Chen, Guanghao Zhu, Xinqiu Song, Lili Cheng, Bo Liu, Jie Liu, Jie Ren   +12 more
wiley   +1 more source

Semiconducting Open‐Shell Radicals for Precise Tumor Activatable Phototheranostics

Advanced Science, EarlyView.
A versatile phototheranostics nanoplatform of tumor‐specific activatable semiconducting open‐shell radicals for precise chemodynamic/photodynamic therapy (CDT/PDT) guided by “Turn On” second near‐infrared (NIR‐II) window fluorescence imaging (FLI) and PA imaging (PAI) through molecular engineering strategies. Abstract Semiconducting open‐shell radicals
Jie Zhang, Haifen Luo, Wen Ma, Jingqi Lv, Bo Wang, Fengwei Sun, Weijie Chi, Zhuting Fang, Zhen Yang   +8 more
wiley   +1 more source

Vascular co‐option and vasculogenic mimicry mediate resistance to antiangiogenic strategies

Cancer Reports, Volume 5, Issue 12, December 2022., 2022
Abstract Background The concept that all the tumors need the formation of new vessels to grow inspired the hypothesis that inhibition of angiogenesis would have led to “cure” cancer. The expectancy that this type of therapy would have avoided the insurgence of resistance was based on the concept that targeting normal vessels, instead of the cancer ...
Francesco Pezzella, Domenico Ribatti
wiley   +1 more source

Existence of global weak solutions to a Cahn-Hilliard cross-diffusion system in lymphangiogenesis [PDF]

arXiv
The global-in-time existence of weak solutions to a degenerate Cahn-Hilliard cross-diffusion system with singular potential in a bounded domain with no-flux boundary conditions is proved. The model consists of two coupled parabolic fourth-order partial differential equations and describes the evolution of the fiber phase volume fraction and the solute ...
arxiv