Results 41 to 50 of about 85,392 (192)
NO‐driven hollow gold Janus nanomotors (HAM) are engineered to improve tumor blood vessel normalization throughout the entire tumor region to enhance T‐cell intratumoral infiltration, and generate and capture whole‐tumor antigens as an in situ cancer vaccine to enhance T‐cell activation, therefore enhancing the antitumor immune response.
Qingping Ma +15 more
wiley +1 more source
Randomized preclinical study of machine perfusion in vascularized composite allografts
This study was designed to identify the optimum machine perfusion parameters for preservation of limbs before transplantation, and determine whether this was better than cold storage. Normothermic machine perfusion at a pressure of 70 mmHg (NMP‐70) provided superior preservation to cold storage after transplantation.
K. R. Amin +7 more
wiley +1 more source
Lymphatic vessels as targets for intervention in the treatment of inflammatory airway diseases [PDF]
J Quint
openalex +1 more source
A solid self‐emulsifying (SSE) platform is loaded with peptide antigens and CpG to form the SSE vaccine. An ApoE‐enriched corona promotes dendritic cell internalization, enabling antigen presentation and T cell activation. Squalene from the SSE also sensitizes T cells by promoting lipid raft formation.
Xueying Shen +8 more
wiley +1 more source
In this study, a Pt/Co BNzyme with peroxidase/GPx‐like activity is developed, increasing oxidative stress by generating ROS and depleting GSH to induce ICD. The mild PTT effect enhanced its enzymatic activity. The Pt/Co BNzyme remodeled the TME, promoting DC maturation.
Yanbing Huang +9 more
wiley +1 more source
Current understanding of gastric cancer immunity remains inadequate, leading to suboptimal immunotherapy outcomes. This study introduces a novel tumor immune microenvironment classification system (Inflamed, Desert, and Excluded), advancing traditional histopathological or molecular subtyping toward a functional immunological framework.
Jianchao Wang +14 more
wiley +1 more source
Evaluation of lymphatic vessel dilatations by anterior segment swept-source optical coherence tomography: case report [PDF]
Éva Volek +3 more
openalex +1 more source
Identifying Key Questions and Challenges in Microchimerism Biology
This study identifies key unanswered questions about microchimerism, the presence of cells from one individual living in another. Experts highlight how these cells may affect health, pregnancy, and disease. This study outlines research priorities and challenges in detecting and studying these rare microchimeric cells, aiming to guide future discoveries
Kristine J. Chua +31 more
wiley +1 more source
An important role of lymphatic vessel activation in limiting acute inflammation [PDF]
Reto Huggenberger +8 more
openalex +1 more source
The Immune Microenvironment in Liver Cancer: From Analysis to Targeting
This review explores how smart nanomedicines overcome the immunosuppressive tumor microenvironment in liver cancer. It details targeted delivery strategies and immune reprogramming mechanisms, including remodeling abnormal physiology, modulating metabolism, and inducing immunogenic cell death. The article highlights the paradigm shift toward multimodal
Jiaming Lan +5 more
wiley +1 more source

