Results 71 to 80 of about 431,164 (300)

Pre‐Regenerative Endothelial Cells Empowered by Antler Blood Exosomes Orchestrate Peripheral Nerve Repair

Advanced Science, EarlyView.
The pre‐regenerative vascular niche (PVN) is essential for nerve repair, yet its endothelial blueprint remains unclear. We identified angiogenic ECs (AECs) as the dominant pre‐regenerative subset and found that antler blood–derived exosomes (AB‐EXO) promote repair via IMP3.
Jinsheng Huang, Qiang Chen, Aihua Jin, Xiaoqi Yang, Hui Zhou, Weiquan Gong, Jin Cheng, Jun Dai, Minjin Wang, Meihua Piao, Yuanyi Wang, Nan Zhou   +11 more
wiley   +1 more source

Anatomy of the ovarian lymphatic vessels.

, 2014
A: The broad ligament has at least two lymphatic routes, one from the ovary and the other from the uterus. To collect lymphatic fluids, the lymphatic vessels were ligated at 15(black arrowhead).
Fumio Sekizawa (525532), Tomas J. Acosta (525533), Mohamad Omar Al-zi’abi (525531), Hironori Abe (502605), Kiyoshi Okuda (502607), Dariusz J. Skarzynski (525534)   +5 more
core   +1 more source

Differential effects of anaesthesia on the contractility of lymphatic vessels in vivo. [PDF]

, 2019
KEY POINTS Contractility of lymphatic collectors is essential for the functionality of the lymphatic system and, thus, for lymph flow. Previously published rates of lymphatic collectors in mice vary from 1.1 to 17 contractions/min with little ...
Miriam Ries, Steven T. Proulx, Yuliang He, Detmar, Michael, Proulx, Steven T., Ries, Miriam, Samia B. Bachmann, Bachmann, Samia B., Ries, Miriam; id_orcid, He, Yuliang, Bachmann, Samia B, Michael Detmar, Proulx, Steven Thomas   +12 more
core   +2 more sources

CALB2 is a Mechanoresistance Gene in Metastatic Prostate Cancer

Advanced Science, EarlyView.
Prostate cancer cell lines of differing origins were cultured over many passages while being subjected to semi‐lethal levels of fluid shear stress, representing the harsh mechanical environment these cells are subjected to in the circulation during the process of distant metastasis.
Abigail R. Fabiano, Allen C. Luo, Paul Taufalele, Jenna A. Dombroski, Ehsan Aalaei, Schyler J. Rowland, Melissa S. Cantú, Alexandria T. Carter, Samantha V. Knoblauch, Cynthia A. Reinhart‐King, Michael R. King   +10 more
wiley   +1 more source

HD‐tDCS Restores Perivascular AQP4 Polarization via PPARγ Modulation to Enhance Glymphatic Clearance After Intracerebral Hemorrhage in Mice

Advanced Science, EarlyView.
HD‐tDCS promotes recovery after intracerebral hemorrhage by enhancing PPARγ‐dependent astrocyte remodeling in a mouse model of ICH. This process suppresses proinflammatory astrocytic activation, restores perivascular AQP4 repolarization, and improves glymphatic influx and efflux, thereby facilitating hematoma and perihematomal edema clearance and ...
Zhiming Li, Yingmei Zhang, Qianqian Tong, Zhitao Gong, Shanyu Zhang, Zhen Qian, Hui Zhang, Qian Yao, Qi Li   +8 more
wiley   +1 more source

Pathophysiology of aged lymphatic vessels

Aging, 2019
Lymphatic vessels maintain body homeostasis by recirculation of fluid and cells. Cell senescence induces lymphatic dysfunction. Impaired contractile function is caused by low muscle cell investiture and decrease of nitric oxide in aged lymphatic collectors, leading to poor drainage of lymph.
Shang, Tongyao, Liang, Jiangjiu, Kapron, Carolyn M., Liu, Ju   +3 more
openaire   +2 more sources

Immediate Growth Control in Response to Boiling Histotripsy is Prognostic for Intratumoral Immune Activation

Advanced Science, EarlyView.
Boiling Histrotripsy (BH), a mechanical form of focused ultrasound (FUS), allows for non‐invasive and non‐ionizing tissue destruction. Utilizing a BH treatment protocol that yielded bifurcating primary tumor growth responses, we found that immediate BH‐induced tumor growth control identifies tumors with acute reductions in antigen‐presenting cells (APC)
Lydia E. Kitelinger, Matthew R. DeWitt, Carly M. Van Wagoner, Claire A. Conarroe, Charles C. Funk, Aaron B. Streit, AeRyon Kim, Richard J. Price, Timothy N. J. Bullock   +8 more
wiley   +1 more source

Histological and biochemical changes in lymphatic vessels after skeletal muscle injury induced by lengthening contraction in male mice

Physiological Reports
Lymphatic vessels are actively involved in the recovery process of inflamed tissues. However, the changes in intramuscular lymphatic vessels during inflammation caused by skeletal muscle injury remain unclear.
Yuma Tamura, Takafumi Kawashima, Rui‐Cheng Ji, Nobuhide Agata, Yuta Itoh, Keisuke Kawakami   +5 more
doaj   +1 more source

Meningeal lymphatic vessel crosstalk with central nervous system immune cells in aging and neurodegenerative diseases

Neural Regeneration Research
Meningeal lymphatic vessels form a relationship between the nervous system and periphery, which is relevant in both health and disease. Meningeal lymphatic vessels not only play a key role in the drainage of brain metabolites but also contribute to ...
Minghuang Gao, Xinyue Wang, Shijie Su, Weicheng Feng, Yaona Lai, Kongli Huang, Dandan Cao, Qi Wang   +7 more
doaj   +1 more source

Enhancement of Lymphatic Vessels in the Superficial Layer in a Rat Model of a Lymphedematous Response

Plastic and Reconstructive Surgery, Global Open, 2018
Background:. The morphologic and histologic behavior of lymphatic vessels in lymphedema has not been well analyzed using laboratory animals. The purpose of the present study was to elucidate the regeneration process of lymphatic vessels after acute ...
Kumiko Matsumoto, MD, Jun Kosaka, MD, DSci, Hiroo Suami, MD, PhD, Yoshihiro Kimata, MD, PhD   +3 more
doaj   +1 more source