Results 91 to 100 of about 509,257 (301)

Optimizing Cancer Vaccinations Using a Physiologically‐Based Pharmacokinetic/Pharmacodynamic (PBPK/PD) Model

open access: yesAdvanced Science, EarlyView.
Where and when should a cancer vaccine be administered? A whole‐body PBPK model demonstrates that systemic immune transport critically determines vaccination efficacy. By simulating how organ‐specific immune interactions influence treatment response, the study provides a quantitative framework for optimizing cancer vaccination strategies.
Mohammad R. Nikmaneshi   +2 more
wiley   +1 more source

Interplay between Inflammatory Responses and Lymphatic Vessels

open access: yes, 2014
Lymphatic vessels are routes for leukocyte migration and fluid drainage. In addition to their passive roles in migration of leukocytes, increasing evidence indicates their active roles in immune regulation.
신기혁, 이승효
core   +1 more source

Lymphatic Vessels

open access: yes, 2017
Lymphatic ...
Elizabeth D Williams (19147639)
core  

Targeting Macrophage‐Mediated Lymphatic Immunosuppression to Prevent Tumor Recurrence After Microwave Ablation

open access: yesAdvanced Science, EarlyView.
Incomplete microwave ablation induces animmunosuppressive microenvironment in tumor‐draining lymph nodes. An albumin‐based lipoprotein nanosystem enables coordinated delivery of immunomodulators to tumor‐draining lymph nodes and residual tumors, reverses post‐ablation immunosuppression, suppresses residual tumor growth, and promotes durable antitumor ...
Xuexia Shan   +14 more
wiley   +1 more source

Aged Lymphatic Vessels and Mast Cells in Perilymphatic Tissues

open access: yes, 2017
This review provides a comprehensive summary of research on aging-associated alterations in lymphatic vessels and mast cells in perilymphatic tissues.
Cynthia Meininger   +2 more
core   +1 more source

Lymphatic and blood vessels in scleroderma skin, a morphometric analysis [PDF]

open access: yes, 2010
Vascular involvement is frequent in systemic sclerosis, but the role of the lymphatic vasculature is poorly known. Our aim was to evaluate lymphatic vessels in systemic sclerosis skin lesions.
SESTINI P.   +7 more
core   +1 more source

Flexible Integration of Structurally Diverse Spatial Multi‐Omics With AgaeSMO

open access: yesAdvanced Science, EarlyView.
AgaeSMO is a versatile and robust deep learning framework for flexible cross‐integration of spatial multi‐omics data. Leveraging a GATs network with a graph attention module, it learns joint embedding across diverse modalities, enabling integration of both structurally paired (e.g., spatial transcriptome‐epigenome, transcriptome‐proteome, transcriptome‐
Kunpeng Liu   +9 more
wiley   +1 more source

Blood flow reprograms lymphatic vessels to blood vessels

open access: yes, 2012
Human vascular malformations cause disease as a result of changes in blood flow and vascular hemodynamic forces. Although the genetic mutations that underlie the formation of many human vascular malformations are known, the extent to which abnormal blood
Chiu-Yu Chen   +30 more
core   +1 more source

Sustainable Hydrogel‐Forming Microneedle‐Reservoir Patches for Transdermal Delivery of Hydrophilic Macromolecules: Biopolymers, Green Manufacturing and Translation

open access: yesAdvanced Science, EarlyView.
Hydrogel‐forming microneedle (HFMN)‐reservoir patches provide a modular route for controlled transdermal delivery of hydrophilic biomacromolecules. The platform integrates skin‐barrier penetration, sustainable biopolymers, scalable green manufacturing, hydration‐driven transport, model‐cargo validation, and translational quality requirements.
Siddharth Mohanty   +4 more
wiley   +1 more source

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