Results 91 to 100 of about 89,203 (261)

Visualising lymphatic flow dynamics during complex physical therapy: A photoacoustic imaging study

JPRAS Open
Background: Complex physical therapy (CPT), which combines compression and exercise therapies, is the cornerstone of lymphedema treatment. However, assessing lymphatic flow in living humans is challenging owing to the small size and transparent nature of
Yushi Suzuki, Hiroki Kajita, Anna Oh, Shiho Watanabe, Yoshifumi Takatsume, Nobuaki Imanishi, Hisashi Sakuma, Tetsuya Tsuji, Kazuo Kishi   +8 more
doaj   +1 more source

Microfluidic Valve‐Integrated Garment for Smooth Sequential Gradient Mechanotherapy

Advanced Intelligent Systems, EarlyView.
We present a soft wearable sleeve that delivers smooth, gap‐free compression using overlapping air‐filled actuators and tiny microfluidic valves. The system reduces bulk, lowers power needs, and uses a smartphone‐sized control box. It can provide sequential gradient compression, gradient pressure holding, and fast deflation, supporting more portable ...
Run Ze Gao, Chen Xi Huang, Drew M. Werbowski, Jacqueline Mary Kormylo, Clark R. Dickerson, Carolyn L. Ren   +5 more
wiley   +1 more source

3D imaging and single-cell analysis reveal cellular heterogeneity of lymphatic valve endothelial cell types

iScience
Summary: Lymphatic vasculature has specialized vessels to support unidirectional interstitial fluid transport and immune surveillance. Although the lymphatic system is a critical actor in skin homeostasis, the spatial organization of the lymphatic ...
Emmanuelle Marchaud, Renaud Morin, Jason S. Iacovoni, Tangra Draia-Nicolau, Aurélie Gomes, Marine Norlund, Pascale Bernes-Lasserre, Jean-Michel Lagarde, Anne-Catherine Prats, Barbara Garmy-Susini, Anne Bouloumie, Anaïs Briot, Florence Tatin   +12 more
doaj   +1 more source

Characterisation of ovine lymphatic vessels in fresh specimens.

PLoS ONE, 2019
Background and aimThe development and use of experimental models using lymphatic cannulation techniques have been hampered by the lack of high-quality colour imaging of lymphatic vessels in situ.
Hung-Hsun Yen, Christina M Murray, Elizabeth A Washington, Wayne G Kimpton, Helen M S Davies   +4 more
doaj   +1 more source

POEMS Syndrome: 2026 Update on Diagnosis, Risk‐Stratification, and Management

American Journal of Hematology, EarlyView.
ABSTRACT Disease Overview POEMS syndrome is a life‐threatening syndrome due to an underlying plasma cell neoplasm. The major criteria for the syndrome are polyneuropathy, clonal plasma cell disorder (PCD), sclerotic bone lesions, elevated vascular endothelial growth factor, and the presence of Castleman disease.
Angela Dispenzieri
wiley   +1 more source

Lymphatic Abnormalities in Noonan Syndrome Extend Beyond Clinically Apparent Disease

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Lymphatic disease represents a well‐described manifestation of Noonan syndrome (NS), yet the full phenotypic spectrum remains incompletely characterized, especially in asymptomatic individuals. We conducted a cross‐sectional study including 10 individuals with NS (four with peripheral lymphedema and six without) and 10 age‐ and sex‐matched ...
Inger Norlyk Sheyanth, Benjamin Kelly, Sheyanth Mohanakumar, Steffen Ringgaard, Yoav Dori, Irene Kibæk Nielsen, Uffe Birk Jensen, Vibeke Elisabeth Hjortdal   +7 more
wiley   +1 more source

A mouse model of mechanical stress injury to the basal ganglia using thermosensitive PNIPAM hydrogel for intracerebral hemorrhage research

Animal Models and Experimental Medicine, EarlyView.
In this study, we established a novel mouse model of intracerebral hemorrhage (ICH) by stereotactically injecting thermosensitive PNIPAM hydrogel into the internal capsule to impose localized mechanical stress on the corticospinal tract, which provides a straightforward and reproducible tool for preclinical studies on focal mechanical stress–induced ...
Mingxi Li, Yujie Chen, Rongsu Huang, Min Xia, Chao Mi, Yuan Tian, Peiwen Guo, Taotao Jin, Shilei Hao, Hua Feng, Yujie Chen, Zhi Chen   +11 more
wiley   +1 more source

Establishment and characterization of mouse lymph node fibrosis models

Animal Models and Experimental Medicine, EarlyView.
The design of the entire paper. Schematic illustration of four strategies for establishing mouse lymph node (LN) fibrosis models. The study further compares their fibrotic remodeling patterns and immune alterations. Abstract Background Lymph node (LN) fibrosis occurs in a variety of pathological conditions, including HIV infection, obesity, cancer, and
Yaru Niu, Xu Guan, Jian Ma, Xin Zhang, Yihang Shi, Jinzhu Zhang, Leiqiong Gao, Wei Chen, Xishan Wang   +8 more
wiley   +1 more source

Rewriting Tumor Immunity With Bacterial Membrane Vesicles: A Versatile and Potent Therapeutic Strategy

Advanced NanoBiomed Research, EarlyView.
Bacterial membrane vesicles (BMVs) emerge as promising platforms for cancer immunotherapy owing to their intrinsic adjuvant properties and tunable cargo delivery capabilities. Their ability to modulate the tumor microenvironment, enhance antitumor immune responses, and support personalized therapeutic strategies highlights their growing potential as ...
Md Sifat Rahi, Md Mijanur Rahman, Asma Talukder, Urooj Yousaf Virk, Jennifer C. Wilson, Nigel McMillan, Ming Q. Wei   +6 more
wiley   +1 more source

Percutaneous Lymphatic Contrast-enhanced Ultrasound for Preoperative Localization in Stage 2–3 Lymphedema: A Feasibility Study

Plastic and Reconstructive Surgery, Global Open
Background:. Lymphaticovenous anastomosis (LVA) is a crucial surgical method for treating lymphedema by reconstructing lymphatic pathways. The success and efficacy of LVA rely on accurate preoperative localization of functional lymphatic vessels.
Lanjing Wu, MD, Shufang Yuan, MD, Liping Chen, MD, Chenyang Zhao, MD, Nan Zhuang, MD, Yi Chen, MD, Sirui Liu, MD, Xia Liu, MD, Jingjing Wen, MD, Longbiao Yu, MD, Zhegang Zhou, MD, Desheng Sun, MD, Zhengming Hu, MD   +12 more
doaj   +1 more source