Results 91 to 100 of about 145,040 (309)

Verrucous venous malformation [PDF]

, 2019
Verrucous venous malformation, also known as verrucous hemangioma, is a superficial vascular malformation with a variable degree of hyperkeratosis that is composed of capillaries and veins in the dermis and sometimes subcutaneous tissue. We describe a 53-
Kim, Gene H, Leavens, Joan, Worswick, Scott   +2 more
core  

Quantitative assessment of angiogenesis in murine antigen-induced arthritis by intravital fluorescence microscopy [PDF]

, 2003
Inhibition of angiogenesis might be a therapeutic approach to prevent joint destruction caused by the overgrowing synovial tissue during chronic joint inflammation.
Krombach, F., Landes, J., Messmer, K., Pellengahr, C., Refior, H. J., Schmitt-Sody, M., Veihelmann, A., Zysk, S. P.   +7 more
core   +1 more source

Tailoring Vascular‐Immune Homeostasis via Manganese‐DNA Complex‐Armed Immunogenic Extracellular Vesicles for Pancreatic Cancer Immunotherapy

Advanced Science, EarlyView.
This study demonstrates that Mn2⁺–tumor DNA complexes encapsulated in dendritic cell (DC)– derived immunogenic extracellular vesicles (EVDC@Mn‐DNA) act as a DC‐specific cGAS– STING activator. EVDC@Mn‐DNA treatment enhances intratumoral DC activation, improves tumor vascular function, promotes CD8⁺ T cell activity, and suppresses pancreatic tumor growth,
Xue Jiang, Lihuan Shang, Xiaochun Chen, Xiangzhan Kong, Xiaojuan Wang, Linjia Jiang, Huiying Zhao, Yafeng Zhu, Cheng Huang, Shiyi Deng, Rui Zhang, Minghui Wang, Haoming Lin, Ping‐Pui Wong   +13 more
wiley   +1 more source

Lymphatic imaging to assess rheumatoid flare: mechanistic insights and biomarker potential [PDF]

, 2016
Proliferation of draining lymphatic vessels coupled with dynamic changes in lymph node volume and flow are characteristic features in rheumatoid arthritis (RA).
Christopher T. Ritchlin, Echoe M. Bouta, Edward M. Schwarz, Homaira Rahimi, Lianping Xing, Richard Bell, Ronald W. Wood   +6 more
core   +1 more source

Marburg Virus Glycoprotein Is a Remarkable Virulent Factor Linked to Hemorrhagic Pathology: Evidence from Multimodal Experimental Systems

Advanced Science, EarlyView.
By integrating data from in vitro, ex vivo, and in vivo models, our research identifies the MARV glycoprotein as a remarkable hemorrhagic factor, filling a major gap in this important field. It also provides practical experimental tools for the basic research on viral pathogenesis and applied research aimed at antiviral intervention for hemorrhagic ...
Ting Yao, Hang Liu, Yanfeng Yao, Wei Deng, Jiawen Sun, Zhenyu Kang, Ashaq Ali, Chao Shan, Zhiming Yuan, Fei Deng, Hualin Wang, Yun‐Jia Ning   +11 more
wiley   +1 more source

Effects of ionizing radiation on normal and tumor-associated lymphatic vessels [PDF]

, 2007
Thesis (S.B.)--Massachusetts Institute of Technology, Dept. of Nuclear Science and Engineering, 2007."June 2007."Includes bibliographical references (p. 37-43).Lymphatic vessels play a crucial role in both the pathophysiology of tumors and in the spread ...
Lobo, Jennifer D
core  

DLL4 promotes continuous adult intestinal lacteal regeneration and dietary fat transport. [PDF]

, 2015
The small intestine is a dynamic and complex organ that is characterized by constant epithelium turnover and crosstalk among various cell types and the microbiota.
Barker, Benedito, Cansaran Saygili Demir, Christophe Cisarovsky, Freddy Radtke, Humphrey, Jeremiah Bernier-Latmani, Jurisic, Kamba, Malanchi, Marine Bruand, Muriel Jaquet, Nowotschin, Olivier Dormond, Prewett, Rui Benedito, Sanjiv A. Luther, Shutter, Simone Ragusa, Srinivas, Stefanie Siegert, Suzel Davanture, Tatiana V. Petrova, Womack   +23 more
core   +2 more sources

Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy

Advanced Science, EarlyView.
Lactate, once deemed a metabolic waste, emerges as a central regulator of cancer progression. This review elucidates how lactate and its epigenetic derivative, protein lactylation, orchestrate tumor metabolism, immune suppression, and therapeutic resistance.
Jiajing Gong, Yuhang Xie, Zhijie Weng, Yongzhi Wu, Longjiang Li, Bo Li   +5 more
wiley   +1 more source

Macrophages recruited by implanted fibrin gels promote regeneration of injured lymphatic vessels

Scientific Reports
Secondary lymphedema is a debilitating condition driven by impaired regeneration of lymphatic vasculature following lymphatic injury, surgical removal of lymph nodes in cancer patients, or infection.
Mohammad S. Razavi, Pin-Ji Lei, Zohreh Amoozgar, Meghan J. O’Melia, Kangsan Roh, Nichaluk Leartprapun, Seemantini K. Nadkarni, James W. Baish, Timothy P. Padera, Lance L. Munn   +9 more
doaj   +1 more source

Decoding Triphenotypic Neutrophils in Cervical Cancer Evolution and Targeting SPP1+/GBP1+/ELOVL5+ Tumor‐Associated Neutrophils to Sensitize Immunotherapy

Advanced Science, EarlyView.
The functional schematic diagram of tumor associated neutrophils. Abstract Enhancing cervical cancer (CC) immunotherapy requires deciphering the heterogeneous tumor immune microenvironment (TIME), particularly neutrophil phenotypic dynamics. Here, 1) we collected 543 CC cases to find that patients with elevated neutrophil levels have a higher incidence
Xingyu Chang, Xinyu Qu, Tingting Ren, Tong Wu, Weiyong Gu, Jingxin Ding, Keqin Hua, Junjun Qiu   +7 more
wiley   +1 more source