Results 91 to 100 of about 160,145 (308)

CytoScan: Automated Detection of Technical Anomalies for Cytometry Quality Control

Cytometry Part A, EarlyView.
ABSTRACT Studies evaluating cellular phenotypes by cytometry techniques are increasingly facing analytical challenges due to the multitudes of samples and parameters that are evaluated concurrently. Spurious technical effects resulting from a lack of standardization can affect marker distributions and further complicate multi‐sample analyses.
Tim R. Mocking, Felix Zwolle, Yejin Park, Angèle Kelder, Yvan Saeys, Jacqueline Cloos, Sofie van Gassen, Costa Bachas   +7 more
wiley   +1 more source

Prognostic implications of mutations and expression of the Wilms tumor 1 (WT1) gene in adult acute T-lymphoblastic leukemia

Haematologica, 2010
Background The role of the Wilms tumor 1 gene (WT1) in acute leukemias has been underscored by mutations found in acute myeloid leukemia identifying patients with inferior survival.
Sandra Heesch, Nicola Goekbuget, Andrea Stroux, Jutta Ortiz Tanchez, Cornelia Schlee, Thomas Burmeister, Stefan Schwartz, Olga Blau, Ulrich Keilholz, Antonia Busse, Dieter Hoelzer, Eckhard Thiel, Wolf-Karsten Hofmann, Claudia D. Baldus   +13 more
doaj   +1 more source

Flow cytometry‐based monitoring of chimeric antigen receptor (CAR) T cells: Reagent selection, assay design, and clinical utility

Cytometry Part B: Clinical Cytometry, EarlyView.
Abstract Accurate quantification of chimeric antigen receptor (CAR) T cells is essential for monitoring post‐infusion CART expansion and persistence and for real‐time clinical decision‐making. Multiparameter flow cytometry (MFC) enables rapid, live‐cell detection with absolute quantification and concurrent immunophenotypic characterization. This review
Jianhua Ling, Wei Wang, Sa A. Wang
wiley   +1 more source

Addendum: B-cell lymphoblastic lymphoma following intravenous BNT162b2 mRNA booster in a BALB/c mouse: a case report

Frontiers in Oncology, 2023
Sander Eens, Sander Eens, Manon Van Hecke, Kasper Favere, Kasper Favere, Kasper Favere, Kasper Favere, Thomas Tousseyn, Pieter-Jan Guns, Tania Roskams, Hein Heidbuchel, Hein Heidbuchel   +11 more
doaj   +1 more source

Clinical, Radiologic and Cytologic Predictors of Malignancy in Pediatric Thyroid Nodules: Insights From a 26‐Year Cohort Study

Head &Neck, EarlyView.
ABSTRACT Introduction Thyroid nodules are less common but more often malignant in pediatric patients than in adults. Our objectives were to study the features of benign vs. malignant thyroid nodules in a large pediatric patient cohort. Methods Retrospective observational cohort study. Consecutive patients aged 0.01–17.9 years at evaluation between 1997–
Maxime Gest‐Laurent, Adrien Nguyen Quoc, Christine Lefevre, Laura González‐Briceño, Caroline Thalassinos, Isabelle Flechtner, Dulanjalee Kariyawasam, Yamina Dassa, Magali Viaud, Dinane Samara‐Boustani, Graziella Pinto, Hervé Monpeyssen, Sabine Sarnacki, Vincent Couloigner, Michel Polak, Athanasia Stoupa   +15 more
wiley   +1 more source

Implantação da análise do conteúdo de DNA por citometria de fluxo para avaliação do prognóstico de hemopatias malignas nos pacientes atendidos pelo serviço de hematologia do Hospital Universitário da Universidade Federal de Santa Catarina [PDF]

, 2014
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Programa de Pós-graduação Multidisciplinar em Saúde, Florianópolis, 2014Os cânceres são doenças que apresentam expansão clonal descontrolada de células ...
Mengatto, Vanessa
core  

HI A ASSOCIATION WITH CHILDHOOD ACUTE LYMPHOBLASTIC LEUKEMIA

مجلة كلية الطب, 2005
Summary: OBJECTIVE Many associations have been found between specific HLA antigens and increased susceptibility to various diseases . So we tried to associate class I and class II antigens with acute lymphoblastic leukemia .
BATOOL M. MAHDI, salalwa M. Shareef
doaj   +1 more source

ATP Citrate Lyase in Metabolic Disease: Mechanistic Insights and Clinical Potential

iNew Medicine, EarlyView.
ATP citrate lyase (ACLY) is a central metabolic hub that diverts mitochondrial citrate to fuel de novo lipogenesis, cholesterol biosynthesis, and protein acetylation. Given its robust correlation with pathological changes in multiple human diseases, ACLY inhibitors featuring distinct pharmacological strengths have been developed for therapeutic ...
Wenbiao Wang, Xinyan Li, Honglu Shi, Gaolei Song, Zhifu Xie, Jingya Li   +5 more
wiley   +1 more source

Emerging Pharmacotherapies for Adult Patients with Acute Lymphoblastic Leukemia

, 2012
Acute lymphoblastic leukemia (ALL) treatment regimes are amongst the longest, most intensive and complex used in hemato-oncology. Despite this, while treatment of pediatric ALL is a success story, we are far from being able to ensure a durable response ...
Lydia Lee, Adele K. Fielding
core   +1 more source

Metabolic feature profiling and metabolic vulnerability in acute lymphoblastic leukemia

Interdisciplinary Medicine, EarlyView.
For the first time, our study develops a novel metabolic classification and subtyping program, metabolic reprogramming‐based classifier for acute lymphoblastic leukemia, using internal PDT‐ALL‐2016 and external cohorts, which dissects metabolic profiling, clinical outcome, and therapeutic vulnerability for precision metabolic intervention in ALL ...
Xiaojie Liang, Zihong Cai, Bingqing Tang, Zicong Huang, Baiwei Luo, Bingyu Lin, Yunong Yang, Zhihao Jin, Xiaoqing Li, Xiuli Xu, Yeling Deng, Chaoran Lin, Liang Wang, Hongsheng Zhou   +13 more
wiley   +1 more source