Results 91 to 100 of about 164,625 (307)

Characteristics of patients with acute lymphoblastic leukemia.

open access: yes, 2016
Characteristics of patients with acute lymphoblastic leukemia.
Sheng-Hsuan Chien (2146708)   +6 more
core   +1 more source

Regulatory harmonization: Evolution, globalization and future directions

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Regulatory harmonization has become an increasingly important and accepted approach to streamline regulatory review processes and expedite access to safe, effective and high‐quality medicines globally. This review explores the evolution and current status of regulatory harmonization, convergence and reliance initiatives.
Orin Chisholm   +2 more
wiley   +1 more source

Replication analysis confirms the association of ARID5B with childhood B-cell acute lymphoblastic leukemia

open access: yesHaematologica, 2010
Although childhood acute lymphoblastic leukemia is the most common pediatric cancer, its etiology remains poorly understood. In an attempt to replicate the findings of 2 recent genome-wide association studies in a French-Canadian cohort, we confirmed the
Jasmine Healy   +4 more
doaj   +1 more source

Detection of minimal residual disease in acute lymphoblastic leukemia [PDF]

open access: yes, 2010
Deep insight on Detection of minimal residual disease in acute lymphoblastic ...
D Campana, Campana, D
core   +1 more source

Patient‐reported outcomes and medication errors during oral antitumour therapy in paediatrics: Results from the youngAMBORA care programme

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aim Increasing use of oral antitumour therapeutics (OAT) in paediatrics is associated with numerous advantages, but also with error‐prone aspects. Based on the randomized AMBORA trial including adults treated with various OAT, we developed a tailored pharmacological/pharmaceutical care programme for children and their caregivers during OAT treatment ...
Phyllis Lensker   +4 more
wiley   +1 more source

Autologous stem cell transplantation for malignancy: a systematic review of the literature

open access: yes, 2000
A systematic review of the literature was undertaken to assess what published evidence is currently available to support the increasing use of autologous stem cell transplantation (ASCT), and to evaluate the published data with regard to the comparative ...
Simnett, S.J.   +4 more
core   +1 more source

Pediatric T-cell acute lymphoblastic leukemia and T-cell lymphoblastic lymphoma therapy

open access: yes, 2009
T-cell acute lymphoblastic leukemia and T-cell lymphoblastic lymphoma in childhood are recognized to be two different pathologies with different biological basis and are treated according to different pediatric ...
R. Rondelli   +2 more
core   +1 more source

Flow cytometry‐based monitoring of chimeric antigen receptor (CAR) T cells: Reagent selection, assay design, and clinical utility

open access: yesCytometry Part B: Clinical Cytometry, EarlyView.
Abstract Accurate quantification of chimeric antigen receptor (CAR) T cells is essential for monitoring post‐infusion CART expansion and persistence and for real‐time clinical decision‐making. Multiparameter flow cytometry (MFC) enables rapid, live‐cell detection with absolute quantification and concurrent immunophenotypic characterization. This review
Jianhua Ling, Wei Wang, Sa A. Wang
wiley   +1 more source

Prognostic implications of mutations and expression of the Wilms tumor 1 (WT1) gene in adult acute T-lymphoblastic leukemia

open access: yesHaematologica, 2010
Background The role of the Wilms tumor 1 gene (WT1) in acute leukemias has been underscored by mutations found in acute myeloid leukemia identifying patients with inferior survival.
Sandra Heesch   +13 more
doaj   +1 more source

Clinical, Radiologic and Cytologic Predictors of Malignancy in Pediatric Thyroid Nodules: Insights From a 26‐Year Cohort Study

open access: yesHead &Neck, EarlyView.
ABSTRACT Introduction Thyroid nodules are less common but more often malignant in pediatric patients than in adults. Our objectives were to study the features of benign vs. malignant thyroid nodules in a large pediatric patient cohort. Methods Retrospective observational cohort study. Consecutive patients aged 0.01–17.9 years at evaluation between 1997–
Maxime Gest‐Laurent   +15 more
wiley   +1 more source

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