Results 11 to 20 of about 160,145 (308)
Obesity and metabolic syndrome in adolescent survivors of standard risk childhood acute lymphoblastic leukemia in Saudi Arabia [PDF]
, 2012 This study estimated prevalence of unhealthy weight status and metabolic syndrome (MS) amongst Saudi survivors of standard risk ALL. Procedure. We recruited 56 survivors, mean age 13.4 years (SD 4.1), a mean of 9.1 years (SD 4.1) postdiagnosis.Aldhafiri, Fahad, Al-Sugair, Abdulaziz, Al-Mutairi, Hanan, Reilly, John J, Al-Nasser, Abdallah, Young, David +5 morecore +4 more sourcesB-Acute Lymphoblastic Leukemia/Lymphoblastic Lymphoma [PDF]
American Journal of Clinical Pathology, 2015 This session of the 2013 Society of Hematopathology/European Association for Haematopathology Workshop was dedicated to B-acute lymphoblastic leukemia (B-ALL)/lymphoblastic lymphoma (LBL) with recurrent translocations and not otherwise specified.In this review, we summarize the cases discussed during the workshop, review the pertinent and most recent ...Sanam, Loghavi, Jeffery L, Kutok, Jeffrey L, Jorgensen +2 moreopenaire +2 more sourcesA dyad of lymphoblastic lysosomal cysteine proteases degrades the antileukemic drug l-asparaginase [PDF]
, 2009 l-Asparaginase is a key therapeutic agent for treatment of childhood acute lymphoblastic leukemia (ALL). There is wide individual variation in pharmacokinetics, and little is known about its metabolism.Vaskar Saha, Krishnan, S., Holland, Mark, Colin Watts, Mark Holland, Holland, M., Liu, JiZhong, Ariffin, Hany, Bates, P.A., Marcin Krol, Paul A. Bates, Moss, Catherine X., Patel, N., Essink, M., Patel, Naina, Clare Dempsey, Krishnan, Shekhar, van Delft, Frederik W., Watts, Colin, Carly Leighton, Leighton, Carly, Eden, T.O.B., Moss, C.X., Offman, Marc N., JiZhong Liu, Dempsey, Clare, Seema Alexander, Hany Ariffin, Bates, Paul A., Dempsey, C., Eden, Tim O B, Alexander, S., van Delft, F.W., Frederik W. van Delft, Watts, C., Offman, M.N., Saha, V., Leighton, C., Eden, Tim O.B., Saha, Vaskar; id_orcid, Shekhar Krishnan, Monika Essink, Saha, Vaskar, Krol, Marcin, Ariffin, H., Tim O.B. Eden, Naina Patel, Alexander, Seema, Catherine X. Moss, Krol, M., Marc N. Offman, Liu, J.Z., Essink, Monika, Van Delft, Frederik W, Offman, Marc N, Bates, Paul A, Moss, Catherine X, Dempsey, Clare E +57 morecore +1 more sourceAcute lymphoblastic leukemia [PDF]
Pediatric Blood & Cancer, 2021 AbstractThe survival of patients with acute lymphoblastic leukemia (ALL) has improved significantly with the use of intensive multimodality treatment regimens including chemotherapy, high‐dose chemotherapy and stem cell rescue, and radiation therapy when indicated.John Han‐Chih Chang, Matthew M. Poppe, Chia‐Ho Hua, Karen J. Marcus, Natia Esiashvili +4 moreopenaire +2 more sourcesEpigenetic landscape correlates with genetic subtype but does not predict outcome in childhood acute lymphoblastic leukemia [PDF]
, 2015 Although children with acute lymphoblastic leukemia (ALL) generally have a good outcome, some patients do relapse and survival following relapse is poor.Mitchell, Chris D, Steven C Clifford (779057), Gabriel, Alem, Clifford, Steven, Schwalbe, Edward C, Mitchell, Chris, Nakjang, Sirintra, Alem S Gabriel (779049), Clifford, Steven C, Lafta, Fadhel M, Strathdee, Gordon, Simon J Cockell (779052), Kinsey, Sally, Vikki Rand (779056), Iliasova, Alice, Christine J Harrison (779061), Schwalbe, Ed, Harrison, Christine, Anthony V Moorman (779062), Lafta, Fadhel, Kinsey, Sally E, Sally E Kinsey (779058), Chris D Mitchell (779059), Vora, Ajay, Cockell, Simon J, Rand, Vikki, Edward C Schwalbe (779051), Gordon Strathdee (779063), Enshaei, Amir, Sirintra Nakjang (124590), Harris, Christine J, Gabriel, Alem S, Moorman, Anthony, Amir Enshaei (779054), Fadhel M Lafta (779050), Claire Schwab (779055), Moorman, Anthony V, Rand, Vikki; id_orcid, Schwab, Claire, Ajay Vora (779060), Cockell, Simon, Alice Iliasova (779053) +41 morecore +1 more sourceInduction therapy for adults with acute lymphoblastic leukemia: results of more than 1500 patients from the international ALL trial: MRC UKALL XII/ECOG E2993 [PDF]
, 2005 The international acute lymphoblastic leukemia (ALL) study was designed to prospectively define the optimal therapy for adults 60 years of age or younger with newly diagnosed ALL.Burnett, Alan Kenneth, Franklin, IM, Rowe, Jacob M., Richards, SM, Litzow, Mark R., Wiernik, P.H., Tallman, Martin S., Rowe, JM, Prentice, H. Grant, Goldstone, Anthony H., Wiernik, PH, Litzow, M.R., Litzow, MR, Ciobanu, N, Ciobanu, N., Prentice, HG, Durrant, J., Richards, Susan M., Durrant, J, Lazarus, H.M., Goldstone, A.H., Chopra, R, Lazarus, Hillard M., Wiernik, Peter H., Ciobanu, Niculae, Rowe, J.M., Tallman, MS, Durrant, Jill, Chopra, R., Lazarus, HM, Burnett, AK, Burnett, A.K., Buck, Georgina, Buck, G., Franklin, Ian M., Chopra, Raj, Goldstone, AH, Prentice, H.G., Richards, S.M., Tallman, M.S., Buck, G, Franklin, I.M. +41 morecore +1 more sourceIn vivo imaging enables high resolution preclinical trials on patients' leukemia cells growing in mice. [PDF]
, 2012 Xenograft mouse models represent helpful tools for preclinical studies on human tumors. For modeling the complexity of the human disease, primary tumor cells are by far superior to established cell lines.zur Stadt, Udo, Groiss, Volker, Schneider, Katja, Renier J Brentjens, Nadia Terziyska, Harald Ehrhardt, Jeremias, I., Brentjens, Renier J., Farkasova, K., Katja Schneider, Volker Groiss (106787), Katarina Farkasova (106794), Ehrhardt, Harald, Wagner, E., Renier J. Brentjens (106801), Quintanilla-Martinez, Leticia, Martin Horstmann (45040), Ehrhardt, H., Ernst Wagner (60760), Wagner, Ernst, Leticia Quintanilla-Martinez (33277), Terziyska, N., Katja Schneider (106791), Horstmann, M., Brentjens, R.J., Catarina Castro Alves, Quintanilla-Martinez, L., Zur Stadt, U., Horstmann, Martin, Schneider, K., Ogris, M., Manfred Ogris, Alves, C.C., Nadia Terziyska (106777), Terziyska, Nadia, Jeremias, Irmela, Groiss, V., Irmela Jeremias (106806), Volker Groiss, Udo zur Stadt, Martin Horstmann, Farkasova, Katarina, Ernst Wagner, Irmela Jeremias, Ogris, Manfred, Udo zur Stadt (106803), Catarina Castro Alves (106783), Manfred Ogris (60759), Castro Alves, Catarina, Katarina Farkasova, Leticia Quintanilla-Martinez, Harald Ehrhardt (106798) +51 morecore +2 more sourcesClinical and molecular characterization of early T-cell precursor leukemia : a high-risk subgroup in adult T-ALL with a high frequency of FLT3 mutations [PDF]
, 2012 A subgroup of pediatric acute T-lymphoblastic leukemia (T-ALL) was characterized by a gene expression profile comparable to that of early T-cell precursors (ETPs) with a highly unfavorable outcome.Hoelzer, Dieter, Farhadi-Sartangi, Nasrin, Schlee, Cornelia, Hofmann, Wolf-Karsten, Thiel, Eckhard, Burmeister, Thomas, Neumann, Martin, Thibaut, Julia, Gökbuget, Nicola, Heesch, Sandra, Schwartz, Stefan, Benlasfer, Ouidad, Baldus, Claudia +12 morecore +1 more sourceFLT3 mutations in Early T-Cell Precursor ALL characterize a stem cell like leukemia and imply the clinical use of tyrosine kinase inhibitors [PDF]
, 2013 Early T-cell precursor acute lymphoblastic leukemia (ETP-ALL) has been identified as high-risk subgroup of acute T-lymphoblastic leukemia (T-ALL) with a high rate of FLT3-mutations in adults.Hartmut Döhner (276603), Hofmann, Wolf-Karsten, Christian Brandts, Ulrich Dührsen, Eckhard Thiel (66496), Mochmann, Liliana H., Burmeister, Thomas, Lars Fransecky, Neumann, Martin, Döhner, Hartmut, Eckhard Thiel, Nicola Gökbuget, Claudia D Baldus, Martin Griesshammer (276602), Rainer Haas (81562), Sartangi, Nasrin Farhadi, Martin Neumann (276593), Gerhard Ehninger, Schwartz, Stefan, Dieter Hoelzer, Stefan Schwartz (276600), Nicola Gökbuget (276599), Olga Blau, Isabelle Bartram, Bartram, Isabelle, Thiel, Eckhard, Liliana H Mochmann, Wolf-Karsten Hofmann, Thomas Burmeister, Martin Neumann, Martin Griesshammer, Sandra Heesch (276598), Heesch, Sandra, Haas, Rainer, Rainer Haas, Schlee, Cornelia, Fransecky, Lars, Ulrich Dührsen (106782), Griesshammer, Martin, Christian Brandts (276601), Lars Fransecky (276595), Ebru Coskun, Claudia D. Baldus (66494), Isabelle Bartram (276596), Wolf-Karsten Hofmann (66497), Ehninger, Gerhard, Brandts, Christian Hubertus, Baldus, Claudia, Gerhard Ehninger (106788), Dührsen, Ulrich, Hoelzer, Dieter, Cornelia Schlee, Dieter Hoelzer (551), Cornelia Schlee (105296), Ebru Coskun (276594), Gökbuget, Nicola, Sandra Heesch, Liliana H. Mochmann (105294), Hartmut Döhner, Nasrin Farhadi Sartangi, Nasrin Farhadi Sartangi (276597), Thomas Burmeister (276604), Stefan Schwartz, Coskun, Ebru, Olga Blau (276605), Blau, Olga +65 morecore +2 more sourcesGenetic predisposition to porto‐sinusoidal vascular disorder: A functional genomic‐based, multigenerational family study
Hepatology, EarlyView., 2022 A deleterious variant of FCHSD1 results in mTOR pathway overactivation and may cause porto‐sinusoidal vascular disorder (PSVD). The pedigree of the family demonstrated an autosomal dominant disease with variable expressivity. Whole‐genome sequencing and Sanger sequencing both validated the existence of the FCHSD1 variant and the heterozygosity of c ...Jingxuan Shan, André Megarbane, Aziz Chouchane, Deepak Karthik, Ramzi Temanni, Atilio Reyes Romero, Huiying Hua, Chun Pan, Xixi Chen, Murugan Subramanian, Chadi Saad, Hamdi Mbarek, Cybel Mehawej, Eliane Chouery, Sirin W. Abuaqel, Alexander Dömling, Sami Remadi, Cesar Yaghi, Pu Li, Lotfi Chouchane +19 morewiley +1 more source
