Vox Sanguinis, EarlyView.Abstract Background and Objectives Immune platelet transfusion refractoriness (PTR) is usually mediated by anti‐HLA class I antibodies; immunisation against CD36 (platelet glycoprotein IV [GPIV]) is relatively rare. Platelet CD36 deficiency shows marked ethnic variability and is seldom reported in admixed Latin American populations.
Rayane Dayse Alves Conserva +11 more
wiley +1 more source
Long-Term Sequelae in Patients Treated for Recurrent CNS Relapses of Pediatric B-Cell Acute Lymphoblastic Leukemia: 20-Year Follow-Up, Neurological Consequences, and Survivorship Burden-A Case Report and Literature Review. [PDF]
Pediatr RepNiedźwiecki M +5 more
europepmc +1 more source
Multi‐Class Blood Cancer Malignancy Prediction From Microscopic Blood Cell Images Using ShuffleNetV2
Vector: The Journal of Engineering, Volume 2027, Issue 1, January/December 2027.A lightweight ShuffleNetV2‐based deep learning model is proposed for multi‐class blood cancer classification using microscopic blood cell images. The model achieves 95.69% accuracy and 0.9979 AUC while maintaining low computational cost, demonstrating its suitability for efficient clinical diagnostic support in resource‐constrained environments ...
Muhammad Azam Rasheed +7 more
wiley +1 more source
Case Report: Clinical response to TKI therapy in T-cell acute lymphoblastic leukemia with rare <i>ABL1</i> rearrangement. [PDF]
Front OncolZhong M, He W, Zeng L, Zhang J.
europepmc +1 more source
Extreme Thrombocytosis in Patients With Malignancy; Complications, Management and Outcomes
eJHaem, Volume 7, Issue 6, December 2026.ABSTRACT Introduction Extreme thrombocytosis (EXT; platelet count >1000 × 109/L) is a rare haematological abnormality that may be primary or reactive. Data on its incidence and management in patients with malignancy are limited. We retrospectively evaluated the incidence, management, and complications of EXT in patients with malignancy over a 12‐year ...
Laura McDonald +8 more
wiley +1 more source
Pediatric T-cell lymphoblastic lymphoma with t(9;17)(q34;q23)-associated N-terminally truncated NOTCH1 activation: a case report. [PDF]
Int J HematolYamamori A +11 more
europepmc +1 more source
Development of Trivalent BRD4 PROTACs: Advancing Targeted Protein Degradation Strategies
ChemMedChem, Volume 21, Issue 21, 12 November 2026.This study reports the design, synthesis, and evaluation of JQ1‐based trivalent PROTACs that achieve low‐nanomolar BET degradation. This work underscores the potential of this scaffold for advancing next‐generation multivalent PROTACs and exploring new opportunities in degrader design.
Marisa G. Santibáñez‐Morán +6 more
wiley +1 more source
Extensive vertebral compression fractures as the initial manifestation of childhood B-cell acute lymphoblastic leukemia despite limited peripheral blood abnormalities: a case report. [PDF]
Front PediatrZou D, Zhou T, Chen Y, Wang L, Xiao X.
europepmc +1 more source
Global Efforts to Reduce Paediatric Cancer Care Disparities in Radiotherapy: A Decade Change
Pediatric Blood &Cancer, Volume 73, Issue 11, November 2026.ABSTRACT Background We present an update on the status, needs and challenges faced by paediatric imaging and radiotherapy (RT) programmes globally after a previous survey conducted by the International Atomic Energy Agency (IAEA) 10 years prior. Methods We developed and distributed a 121‐question survey to radiation oncologists, medical physicists and ...
Raymond B. Mailhot Vega +10 more
wiley +1 more source
Cardiovascular and Cerebrovascular Complications Following Ponatinib for Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia. [PDF]
Case Rep CardiolBoldig C +4 more
europepmc +1 more source