Results 221 to 230 of about 164,625 (307)

Pharmacogenomics in Cancer Treatment: Challenges and Opportunities in African Settings

Cancer Medicine, Volume 15, Issue 11, November 2026.
ABSTRACT Background Cancer incidence in Africa is projected to reach 2.1 million new cases annually by 2040. Current treatment guidelines remain largely based on pharmacogenomic data predominantly from European and Asian genetic profiles, potentially compromising safety and efficacy in African patients.
Ntombikhona Fortunate Maphumulo, George Rebello, Veron Ramsuran   +2 more
wiley   +1 more source

A Mobile Health Intervention to Reduce Sedentary Behavior Among Adolescents and Early Young Adults Receiving Treatment for Acute Lymphoblastic Leukemia: Protocol for a Single-Arm Feasibility Trial. [PDF]

JMIR Res Protoc
Ivory BJ, Chi YY, Belcher BR, Freyer DR.
europepmc   +1 more source

Acute Promyelocytic Leukemia With PML‐RARA Rearrangement: Clinical and Morphologic Features

Clinical Case Reports, Volume 14, Issue 11, November 2026.
ABSTRACT Recognition of the characteristic morphologic features of acute promyelocytic leukemia on peripheral blood smear should prompt immediate initiation of all‐trans retinoic acid while awaiting confirmatory testing, as early intervention is critical to reducing hemorrhagic mortality and improving clinical outcomes.
Chukwuka Elendu, Ayodeji D. Johnson, Ayi T. Debua   +2 more
wiley   +1 more source

Malignant Hepatic Infiltration Versus Drug-Induced Liver Injury in B-Cell Acute Lymphoblastic Leukemia. [PDF]

ACG Case Rep J
Liu J, Petrosyan A, Yoon J, Roytman M.
europepmc   +1 more source

Clinical Functional Assignment of TPMT and NUDT15 Alleles by the Clinical Pharmacogenetics Implementation Consortium Pharmacogene Curation Expert Panel

Clinical Pharmacology &Therapeutics, Volume 120, Issue 5, Page 1427-1437, November 2026.
The Clinical Pharmacogenetics Implementation Consortium (CPIC) TPMT/NUDT15 Pharmacogene Curation Expert Panel (PCEP) conducted a comprehensive review of clinical, laboratory, and computational evidence to determine the clinical function assignments for TPMT and NUDT15 star alleles.
Bailey M. Tibben, Maud Maillard, Victoria M. Pratt, Ann M. Moyer, Debbie M. Figueroa, Michelle Whirl‐Carrillo, Andrea Gaedigk, Gabriele Stocco, Matthias Schwab, Kelly E. Caudle, Jun J. Yang   +10 more
wiley   +1 more source

RNA‐Binding Protein NOVA1 Restrains Immune Escape and Liver Metastasis in Colorectal Cancer via Stabilizing NRXN1 mRNA

The Journal of Gene Medicine, Volume 28, Issue 11, November 2026.
The RNA‐binding protein neuro‐oncological ventral antigen 1 (NOVA1) is downregulated in colorectal cancer (CRC) and is associated with poor prognosis. NOVA1 binds and stabilizes neurexin 1 (NRXN1) messenger RNA (mRNA), thereby increasing NRXN1 expression and suppressing tumor cell proliferation, invasion, immune evasion, and liver metastasis; NRXN1 ...
ZhiXing Wei, Xing Wei, LinSai Cui, YaXin Pang, Guang Cui, Zhen Wei, ZhaoCai He, BuQiang Wu   +7 more
wiley   +1 more source

Practices of Antifungal Prophylaxis Among Italian Pediatric Oncology-Hematology Centers. [PDF]

EJHaem
Colli M, Grasso A, Spadea M, Compagno F, Chiusaroli L, Muggeo P, Pancaldi A, Mura R, Onofrillo D, De Santis R, Mongelli B, Barone A, Rinieri S, Coccia P, Ricci E, Faraci M, D'Amico MR, Galaverna F, Gasperini P, Brescia L, Colombini A, Masetti R, Baccelli F, Cesaro S.   +23 more
europepmc   +1 more source

Cancer Treatment During Pregnancy and Maternal and Infant Outcomes: A Descriptive Cohort Study Using a Japanese Claims Database

Pharmacoepidemiology and Drug Safety, Volume 35, Issue 11, November 2026.
ABSTRACT Purpose To characterize cancer treatment during pregnancy and maternal and infant outcomes among women with cancer identified during pregnancy in Japan. Methods In this descriptive cohort study, we used mother‐infant linkage data from the JMDC claims database from 2005 to 2024.
Masami Tsuchiya, Tomofumi Ishikawa, Takamasa Sakai, Satoko Hori, Taku Obara   +4 more
wiley   +1 more source

Radiological Findings and Genetic Rearrangements in Paediatric Patients with Acute Lymphoblastic Leukaemia. [PDF]

Appl Clin Genet
Rocka A, Suchcicka M, Woźniak MM, Lejman M.   +3 more
europepmc   +1 more source

Hepatic B‐cell lymphoma in a wild European badger (Meles meles) in the UK

Veterinary Record Case Reports, Volume 14, Issue 4, November 2026.
Abstract Neoplastic diseases are considered rare in wild European badgers (Meles meles) with a single pelioid hepatocellular carcinoma, and four lymphoma cases (two T‐cell, two unclassified) in the literature. A found‐dead, elderly, male wild badger underwent postmortem examination for Mycobacterium bovis surveillance.
Shauna Anne Hilton, Malcolm Bennett, Ana Liza Ortiz, Carlo Bianco   +3 more
wiley   +1 more source