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Acute lymphoblastic leukemia and lymphoblastic lymphoma
2022Oliver G. Ottmann, Liora Schultz
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Nature Reviews Disease Primers
Acute lymphoblastic leukaemia (ALL) is a haematological malignancy characterized by the uncontrolled proliferation of immature lymphoid cells. Over past decades, significant progress has been made in understanding the biology of ALL, resulting in remarkable improvements in its diagnosis, treatment and monitoring.
Luca Pagliaro +10 more
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Acute lymphoblastic leukaemia (ALL) is a haematological malignancy characterized by the uncontrolled proliferation of immature lymphoid cells. Over past decades, significant progress has been made in understanding the biology of ALL, resulting in remarkable improvements in its diagnosis, treatment and monitoring.
Luca Pagliaro +10 more
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2007
Acute lymphoblastic leukemia (ALL) comprises a heterogeneous group of disorders which originate from various important genetic lesions in B and T progenitor cells, including mutations that lead to stage-specific developmental arrest and those that impart the capacity for unlimited self-renewal, resulting in clonal expansion of immature progenitor cells
Biondi A., Scrideli C. A., Cazzaniga G.
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Acute lymphoblastic leukemia (ALL) comprises a heterogeneous group of disorders which originate from various important genetic lesions in B and T progenitor cells, including mutations that lead to stage-specific developmental arrest and those that impart the capacity for unlimited self-renewal, resulting in clonal expansion of immature progenitor cells
Biondi A., Scrideli C. A., Cazzaniga G.
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Acute lymphoblastic leukemia and the lymphoblastic lymphomas of childhood.
Seminars in diagnostic pathology, 1996Recent advances in diagnosis, treatment, and tumor biology of the lymphoid blastic malignancies have challenged historical concepts and created a need for revised classification of these diseases. The authors review this material and present a classification relevant to current therapeutic protocols and available biological data.
D R, Head, F G, Behm
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Lymphoblastic Neoplasms— T-lymphoblastic Leukemia/Lymphoma
2013Faramarz Naeim +3 more
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Extensive Remodeling of the Immune Microenvironment in B Cell Acute Lymphoblastic Leukemia
Cancer Cell, 2020Iannis Aifantis +2 more
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