Results 61 to 70 of about 81,713 (355)

Clonal Hypereosinophilia with ETV6 Rearrangement Evolving to T-Cell Lymphoblastic Lymphoma: A Case Report and Review of the Literature

Case Reports in Hematology, 2013
Hypereosinophilia, either clonal or reactive, has been described in association with multiple hematological malignancies. We describe a case of a patient presenting with hypereosinophilia that evolved into T-cell lymphoblastic lymphoma.
Filipa Moita, Isabel Bogalho, Helena Alaiz, Joana Parreira, Maria Jesus Frade, Albertina Nunes, Maria Gomes da Silva   +6 more
doaj   +1 more source

CBFA2T3::GLIS2‐positive acute leukemia with RAM and mixed T/megakaryocytic phenotype

eJHaem, 2023
Herein, we present a rare case of acute myeloid leukemia (AML) with CBFA2T3‐rearrangement and the expression of megakaryocytic and lymphoid markers, highlighting the need for a high suspicion index in differential diagnosis and applying adequate workup ...
Mahsa Khanlari, Lu Wang, Christine Y Bolen, Felipe Sebastian Bautista Otanez, Larissa V. Furtado, Laura Key, Lisa Irwin, Wei Wang, Jeffery M. Klco   +8 more
doaj   +1 more source

The molecular basis of T cell acute lymphoblastic leukemia [PDF]

, 2012
T cell acute lymphoblastic leukemias (T-ALLs) arise from the malignant transformation of hematopoietic progenitors primed toward T cell development, as result of a multistep oncogenic process involving constitutive activation of NOTCH signaling and ...
Adolfo Ferrando, Bash, Bash, Chen, Condorelli, Dube, Fisch, Hagemeijer, Hebert, Ho, Kelliher, Kikuchi, Larson, Lu, McGuire, McGuire, Nagel, Ntziachristos, Ntziachristos, Ono, Pieter Van Vlierberghe, Royer-Pokora, Rubnitz, van Grotel   +23 more
core   +1 more source

Possible role of human ribonuclease dicer in the regulation of R loops

FEBS Open Bio, EarlyView.
R loops play an important role in regulating key cellular processes such as replication, transcription, centromere stabilization, or control of telomere length. However, the unscheduled accumulation of R loops can cause many diseases, including cancer, and neurodegenerative or inflammatory disorders. Interestingly, accumulating data indicate a possible
Klaudia Wojcik, Paulina Krzeminska, Anna Kurzynska‐Kokorniak   +2 more
wiley   +1 more source

Transformation of a low-grade follicular lymphoma into a composite lymphoma combining a high-grade B-cell lymphoma and a lymphoblastic neoplasm expressing Terminal deoxynucleotidyl Transferase: a case report

Journal of Medical Case Reports, 2020
Background High-grade B-cell lymphoma with rearrangements of MYC and BCL2 and/or BCL6 is an aggressive mature B-cell neoplasm, whereas B-lymphoblastic lymphoma is immature cell proliferation, with a frequent positivity for terminal deoxynucleotidyl ...
Antonin Bouroumeau, Eleonore Kaphan, Clémentine Legrand, Tatiana Raskovalova, Gautier Szymanski, Claire Vettier, Christine Lefebvre, Marie-Christine Jacob, Anne McLeer, Michel Peuchmaur, Rémy Gressin, Hervé Sartelet   +11 more
doaj   +1 more source

Individual quality assessment of autografting by probability estimation for clinical endpoints: a prospective validation study from the European group for blood and marrow transplantation. [PDF]

, 2013
The aim of supportive autografting is to reduce the side effects from stem cell transplantation and avoid procedure-related health disadvantages for patients at the lowest possible cost and resource expenditure.
Campioni, Dc, Cuneo, A, Farge, D, Fiamenghi, C, Fruehauf, S, Hellmann, A, Johnsen, He, Knopińska, W, Lanza, F, Madrigal, A, Milone, G, Mohty, M, Passweg, J, Petriz, J, Quality Assessment of Haematopoietic Stem Cell Grafting Committee of European Blood and Marrow Transplantation Society, Ruuto, T, Spedini, P, Swierkowska-Czeneszew, M, Wahlin, A, Walewski, J   +19 more
core   +1 more source

Recent Applications of Mesoporous Silica Nanoparticles in Gene Therapy

Advanced Healthcare Materials, EarlyView.
The review summarizes the synthesis of mesoporous silica nanoparticles (MSNs) with modifiable surface properties, functionalization strategies, mechanism of therapeutic payload release, and current applications in gene therapy, focusing on their capabilities in the targeted delivery of therapeutic nucleic acids, CRISPR‐Cas systems, and other genetic ...
Tamanna Binte Huq, Punnya Anil Kumar Jeeja, Sudip Kumar Dam, Sabya Sachi Das, Juan L. Vivero‐Escoto   +4 more
wiley   +1 more source

Lymphoblastic lymphoma presenting as soft-tissue swelling – A single-center experience

Iraqi Journal of Hematology
BACKGROUND: Lymphoblastic lymphomas (LBL) are a rare, aggressive type of non-Hodgkin lymphomas and constitute 2% of all lymphomas. It is classified as T-lymphoblastic lymphoma (T-LBL) and B lymphoblastic lymphoma (B-LBL) and resembles acute lymphoblastic
Pallavi Nair, Sugeeth M. Thambi, Geetha Narayanan, Jayasudha A. Vasudevan, Ashwin Mohandas Pallath, Sreejith G. Nair   +5 more
doaj   +1 more source

Case-based Similar Image Retrieval for Weakly Annotated Large Histopathological Images of Malignant Lymphoma Using Deep Metric Learning [PDF]

arXiv, 2021
In the present study, we propose a novel case-based similar image retrieval (SIR) method for hematoxylin and eosin (H&E)-stained histopathological images of malignant lymphoma. When a whole slide image (WSI) is used as an input query, it is desirable to be able to retrieve similar cases by focusing on image patches in pathologically important regions ...
arxiv  

Clinicopathological features of extranodal lymphomas: Kuwait experience [PDF]

, 2004
A total of 935 patients with extranodal non-Hodgkin lymphoma (NHL) diagnosed in the period between January 1985 and December 2000 in Kuwait Cancer Center, serving the whole population of Kuwait, were used to describe the clinicopathological and ...
Bamanikar S, D'Amore F, Ducreux M, F. Sinowatz, Freeman C, Gospodarowicz MK, H. Amanguno, H. Baker, Hauke RJ, J.P. Madda, L. Temmim, Longo DL, Neugut AI, Penn I, Shome DK, Stiller CA, Weisenburger DD, Zeeb H   +17 more
core   +1 more source