Results 11 to 20 of about 597,213 (313)
Dynamic 3D Locus Organization and Its Drivers Underpin Immunoglobulin Recombination
Frontiers in Immunology, 2021 A functional adaptive immune system must generate enormously diverse antigen receptor (AgR) repertoires from a limited number of AgR genes, using a common mechanism, V(D)J recombination.
Carolyn H. Rogers +2 more
doaj +1 more source
Cell Reports, 2017 Adenomatous polyposis coli (APC) is a polarity regulator and tumor suppressor associated with familial adenomatous polyposis and colorectal cancer development.
Sonia Agüera-González +9 more
doaj +1 more source
Antigen-specific electrophoretic cell separation for immunological investigations [PDF]
, 1989 Preincubation of human blood lymphocytes with cell surface antigen specific antibodies under non-capping conditions reduces the electrophoretic mobility of the corresponding lymphocyte subpopulation.
Hannig, K. +2 more
core +1 more source
Polish Journal of Pathology, 2019 Organic basis of gastrointestinal symptoms is in the scope of many specialists. In this article lymphocytic gastritis, relatively newly described and not widely-known entity is presented. The lesion is characterized by presence of numerous mature lymphocytes in the surface and foveolar epithelium, as well as lymphocytic infiltration of the lamina ...
Michał Puderecki +3 more
openaire +4 more sources
Images in cardiovascular medicine : multiphoton microscopy for three-dimensional imaging of lymphocyte recruitment into apolipoprotein-E-deficient mouse carotid artery [PDF]
, 2007 Two recent elegant studies have shown that in apolipoprotein-E– deficient mice, the lamina adventitia is a major site of arterial wall inflammation associated with lymphocyte infiltration into atherosclerotic arteries and with formation of adventitial ...
Baker, Andrew H. +7 more
core +1 more source
Sensitivity of activated human lymphocytes to cyclosporine and its metabolites [PDF]
, 1988 Alloreactive T cells generated as clones from mixed lymphocyte cultures, or propagated from heart or liver transplant biopsies, were tested for secondary proliferation measured in the primed lymphocyte test in the presence of Cyclosporine A and ...
Burckart, G +8 more
core +1 more source
TCD4pos lymphocytosis in rheumatoid and psoriatic arthritis patients following TNFα blocking agents [PDF]
, 2017 BACKGROUND: Lymphocyte expansion and true lymphocytosis are commonly observed in the everyday clinical practice. The meaning of such phenomenon is often poorly understood so that discrimination between benign and malignant lymphocytosis remains ...
Amodeo, Rachele +11 more
core +1 more source
Heterochronic faecal transplantation boosts gut germinal centres in aged mice
Nature Communications, 2019 Microbiota impacts all major aspects of physiology, but little is known about its effects on age-related changes in immune responses. Here the authors show that gut microbiota transfer between adult and old mice increases local but not systemic germinal ...
Marisa Stebegg +6 more
doaj +1 more source
Rejuvenating conventional dendritic cells and T follicular helper cell formation after vaccination
eLife, 2020 Germinal centres (GCs) are T follicular helper cell (Tfh)-dependent structures that form in response to vaccination, producing long-lived antibody secreting plasma cells and memory B cells that protect against subsequent infection. With advancing age the
Marisa Stebegg +14 more
doaj +1 more source
Nature Communications, 2021 The Mediator complex regulates RNA polymerase II transcription in all eukaryotes. The mammalian Mediator cryo-EM structure reveals the architecture of previously unresolved Tail module and suggests its regulatory role in the complex conformation and ...
Haiyan Zhao +6 more
doaj +1 more source