Results 41 to 50 of about 958,254 (366)
T-cell responses in oiled guillemots and swans in a rehabilitation setting [PDF]
This article has been accepted for publication in the Archives of Environmental Contamination and Toxicology. The final version can be accessed from the link below.This article has been made available through the Brunel Open Access Publishing Fund ...
A Balseiro+22 more
core +1 more source
Cell polarity regulators, multifunctional organizers of lymphocyte activation and function
Cell polarity regulators are ubiquitous, evolutionary conserved multifunctional proteins. They contain a variety of protein–protein interaction domains endowing them the capacity to interact with cytoskeleton structures, membrane components and multiple ...
Marta Mastrogiovanni+2 more
doaj
The success of most vaccines relies on the generation of antibodies to provide protection against subsequent infection; this in turn depends on a robust germinal centre (GC) response that culminates in the production of long-lived antibody-secreting ...
Michelle A. Linterman, Danika L. Hill
doaj +1 more source
MHC-independent αβT cells: Lessons learned about thymic selection and MHC-restriction
Understanding the generation of an MHC-restricted T cell repertoire is the cornerstone of modern T cell immunology. The unique ability of αβT cells to only recognize peptide antigens presented by MHC molecules but not conformational antigens is referred ...
François Van Laethem+6 more
doaj +1 more source
The clinical spectrum of SMA‐PME and in vitro normalization of its cellular ceramide profile
Abstract Objective The objectives of this study were to define the clinical and biochemical spectrum of spinal muscular atrophy with progressive myoclonic epilepsy (SMA‐PME) and to determine if aberrant cellular ceramide accumulation could be normalized by enzyme replacement.
Michelle M. Lee+16 more
wiley +1 more source
Polypyrimidine tract-binding proteins are essential for B cell development
Polypyrimidine tract-binding protein 1 (PTBP1) is a RNA-binding protein (RBP) expressed throughout B cell development. Deletion of Ptbp1 in mouse pro-B cells results in upregulation of PTBP2 and normal B cell development.
Elisa Monzón-Casanova+5 more
doaj +1 more source
Flow cytometry allows the simultaneous quantification of many markers in and on a cell, but the analysis of such data is complicated. Here, the authors propose AutoSpill, a framework that facilitates the analysis of such data by automating parts of the ...
Carlos P. Roca+11 more
doaj +1 more source
The association of neutrophil-lymphocyte ratio and lymphocyte-monocyte ratio with 3-month clinical outcome after mechanical thrombectomy following stroke [PDF]
Background and aim Neutrophil-lymphocyte ratio (NLR) and lymphocyte-monocyte ratio (LMR) are associated with clinical outcomes in malignancy, cardiovascular disease and stroke.
Alakbarzade, V+7 more
core +1 more source
Organic basis of gastrointestinal symptoms is in the scope of many specialists. In this article lymphocytic gastritis, relatively newly described and not widely-known entity is presented. The lesion is characterized by presence of numerous mature lymphocytes in the surface and foveolar epithelium, as well as lymphocytic infiltration of the lamina ...
Michał Puderecki+3 more
openaire +3 more sources
LYSTO: The Lymphocyte Assessment Hackathon and Benchmark Dataset [PDF]
We introduce LYSTO, the Lymphocyte Assessment Hackathon, which was held in conjunction with the MICCAI 2019 Conference in Shenzen (China). The competition required participants to automatically assess the number of lymphocytes, in particular T-cells, in histopathological images of colon, breast, and prostate cancer stained with CD3 and CD8 ...
arxiv