Results 161 to 170 of about 4,183,330 (355)

Engineered ETS1‐Nanoconjugate Restores Immune Homeostasis through Dual Immune‐Vascular Modulation in Relapsing and Progressive Multiple Sclerosis

Advanced Healthcare Materials, EarlyView.
The biomimetic nanoplatform IMNP (ETS1 pDNA/PBAE@ITP‐MM) undergoes targeted disassembly at inflammatory vascular sites to release the ETS1 plasmid (pETS1). This release initiates a cascade of effects that inhibit pathogenic pathways and support immune homeostasis. (Abbreviations: EndMT, endothelial‐to‐mesenchymal transition; EC, endothelial cell; TC, T
Feng Zhang, Si‐Bo Yang, Yan Luo, Xiao‐Di Sun, Bo‐Hao Chang, Da‐Qiang Zhou, Jun‐Jie Jiang, Ya‐Nan Li, Jie‐Hong Wu, Hui‐Juan Jin, Hang Yang, Hang Hu, Yi‐Fan Zhou, Bo Hu   +13 more
wiley   +1 more source

Hemoglobin alpha regulates T-lymphocyte activation and mitochondrial function. [PDF]

Front Immunol
Reed EC, Lauten TH, Natour T, Pitts LJ, Jojo CN, Griffin BL, Pasupuleti S, Case AJ.   +7 more
europepmc   +1 more source

Discovery of First-in-Class Small Molecule Inhibitors of Lymphocyte Activation Gene 3 (LAG-3). [PDF]

ACS Med Chem Lett, 2023
Abdel-Rahman SA, Rehman AU, Gabr MT.
europepmc   +1 more source

The WT hemochromatosis protein HFE inhibits CD8+ T‐lymphocyte activation

European Journal of Immunology, 2014
A. Reuben, Mikaël Phénix, Manuela M. Santos, R. Lapointe   +3 more
semanticscholar   +1 more source

Lymphocytes prime activation is required for nicotine-induced calcium waves [PDF]

, 2010
Frank Antonicelli
openalex   +1 more source

Tunable Enhancement of T Cell Expansion Through Modulation of Stiffness and Adhesion Receptor Engagement in an Engineered Hydrogel Platform

Advanced Materials, EarlyView.
We develop a hydrogel scaffold with controlled substrate stiffness and ligand functionalization for cell culture. Stiff substrates presenting CD3/CD28/CD2 ligands induce 2000‐fold expansion of T cells; this is 68% greater than the clinical standard (Dynabeads) and the first hydrogel capable of large‐scale expansion. Although expanding at a lower yield,
Niroshan Anandasivam, Rabia Ali, Lordean Gustinvil, Matthew J. Rosenwasser, Iain E. Dunlop, Derfogail Delcassian   +5 more
wiley   +1 more source

Author Correction: Inactivation of cytidine triphosphate synthase 1 prevents fatal auto-immunity in mice

Nature Communications
Claire Soudais, Romane Schaus, Camille Bachelet, Norbert Minet, Sara Mouasni, Cécile Garcin, Caique Lopes Souza, Pierre David, Clara Cousu, Hélène Asnagli, Andrew Parker, Paul Palmquist-Gomes, Fernando E. Sepulveda, Sébastien Storck, Sigolène M. Meilhac, Alain Fischer, Emmanuel Martin, Sylvain Latour   +17 more
doaj   +1 more source

Remote‐Controllable Immune‐Priming Spot Formation Via Nanocomplexed Hydrogel‐Assisted Histotripsy: Immunoasis

Advanced Materials, EarlyView.
A novel immunotherapeutic strategy combines injectable, adjuvant‐loaded hydrogels with externally controlled histotripsy to create immune‐priming sites within tumors. This approach generates millimeter‐sized immune‐activated lesions with flexible, patient‐tailored treatment scheduling, enabling precise immune activation through tumor ablation‐mediated ...
Sung Hoon Kim, Wonseok Choi, Yurim Kim, Hyeongmin Kim, Gu Won Jeong, Hyewon Park, Inchan Youn, Yoon Park, Sungmin Han, Young‐Min Kim   +9 more
wiley   +1 more source

Expression and prognostic importance of lymphocyte activation gene 3 and CD73 in advanced or metastatic hepatocellular carcinoma. [PDF]

J Int Med Res
Ayhan M, Dogan A, Keser SH, Başak K, Akdeniz N, Atci MM, Erhan SS, Arikan R, Celikel C, Turan N, Yıldırım ME, Odabas H, Yıldırım S, Laçin Ş, Kostek O.   +14 more
europepmc   +1 more source

The relationship between soluble lymphocyte activation gene-3 and coronary artery disease. [PDF]

Front Cardiovasc Med, 2022
Xiong X, Duan Z, Zhou H, Niu L, Luo Z, Li W.   +5 more
europepmc   +1 more source