Results 261 to 270 of about 4,241,016 (384)

Engineering CRISPR System‐Based Bacterial Outer Membrane Vesicle Potentiates T Cell Immunity for Enhanced Cancer Immunotherapy

Advanced Materials, EarlyView.
This study develops a multifunctional CRISPR‐dCas9‐based OMV platform termed OMV‐C9I12, which facilitates the coexpression of CXCL9 and IL‐12 within tumor cells. This platform enhances T cell recruitment and activation, synergizes with anti‐PD‐1/PD‐L1 immunotherapy, and amplifies antitumor T cell immunity.
Hongjin Wang, Hengji Zhan, Bolin Pan, Leli Zeng, Zehua Chen, Sen Liu, Qiang Zhang, Xuwei Hong, Junlin Lu, Xinrou Lin, Xiao Zhao, Jiajian Lai, Kaiwen Jie, Ye Li, Jianmei Zhong, Shengmeng Peng, Siting Chen, Changhao Chen, Wenlong Zhong, Shaoxu Wu, Yihang Pan, Tianxin Lin, Xu Chen   +22 more
wiley   +1 more source

Lymphocyte activation gene 3 served as a potential prognostic and immunological biomarker across various cancer types: a clinical and pan-cancer analysis. [PDF]

Clin Transl Immunology
Liu Y, Yao Y, Yang X, Wei M, Lu B, Dong K, Lyu D, Li Y, Guan W, Huang R, Xu G, Pan X.   +11 more
europepmc   +1 more source

Estrogen Receptor-β Agonists Modulate T-Lymphocyte Activation and Ameliorate Left Ventricular Remodeling During Chronic Heart Failure. [PDF]

Circ Heart Fail, 2022
Rosenzweig R, Kumar V, Gupta S, Bermeo-Blanco O, Stratton MS, Gumina RJ, Bansal SS.   +6 more
europepmc   +1 more source

Elementary immunology [PDF]

, 2017
Gogolák, Péter, Koncz, Gábor
core  

Activation of resting T lymphocytes by anti-CD3 (T3) antibodies in the absence of monocytes. [PDF]

, 1985
Constantine D. Tsoukas, Bryan E. Landgraf, J. Bentin, Mary A. Valentine, Martin Lotz, J H Vaughan, Dennis A. Carson   +6 more
openalex   +1 more source

Harnessing Photo‐Energy Conversion in Nanomaterials for Precision Theranostics

Advanced Materials, EarlyView.
Harnessing photo‐energy conversion in nanomaterials enables precision theranostics through light‐driven mechanisms such as photoluminescence, photothermal, photoelectric, photoacoustic, photo‐triggered surface‐enhanced Raman scattering (SERS), and photodynamic processes. This review explores six fundamental principles of photo‐energy conversion, recent
Jingyu Shi, Yadi Fan, Qin Zhang, Yingying Huang, Mo Yang   +4 more
wiley   +1 more source

Pan-cancer and single-cell analysis reveal dual roles of lymphocyte activation gene-3 (LAG3) in cancer immunity and prognosis. [PDF]

Sci Rep
Wang Y, Zhao Y, Zhang G, Lin Y, Fan C, Wei H, Chen S, Guan L, Liu K, Yu S, Fu L, Zhang J, Yuan Y, He J, Cai H.   +14 more
europepmc   +1 more source

Lymphocyte activation gene (LAG)-3 is a potential immunotherapeutic target for microsatellite stable, programmed death-ligand 1 (PD-L1)-positive endometrioid endometrial cancer. [PDF]

J Gynecol Oncol, 2023
Hong JH, Cho HW, Ouh YT, Lee JK, Chun Y.
europepmc   +1 more source

Interdependence of CD3-Ti and CD2 activation pathways in human T lymphocytes. [PDF]

, 1988
Andrés Alcover, Cristina M. Alberini, Oreste Acuto, Linda K. Clayton, Catherine Transy, Giulio C. Spagnoli, Philippe Moingeon, Peter Lopez, Ellis L. Reinherz   +8 more
openalex   +1 more source

Effect of highly active antiretroviral therapy on biomarkers of B-lymphocyte activation and inflammation

AIDS (London), 2011
Deborah Regidor, R. Detels, E. Breen, Daniel P. Widney, L. Jacobson, F. Palella, C. Rinaldo, J. Bream, O. Martínez-Maza   +8 more
semanticscholar   +1 more source