Results 291 to 300 of about 4,183,330 (355)
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Calcium and lymphocyte activation
Cellular Immunology, 1976Abstract The role of ionized calcium in the early phases of activation of human peripheral blood lymphocytes was evaluated by stimulating the cells with a calcium ionophore A23187 (Lilly) or with mitogenic lections over a broad range of extracellular calcium concentrations ( 1000 μ M ).
W C, Greene, C M, Parker, C W, Parker
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Migration of Activated Lymphocytes
1993When lymphocytes leave the primary lymphoid organs as mature but naive cells, they enter the recirculating pool, moving continuously from the blood into the secondary lymphoid organs, spleen, lymph nodes and Peyer’s patches, from which they return, directly or via efferent lymph, back to the blood (Gowans and Knight 1964).
A, Hamann, S, Rebstock
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The Journal of Immunology, 1978
Abstract Lipopolysaccharide-activated murine peritoneal macrophages elaborate lymphocyte-activating factor (LAF) which is mitogenic for murine thymocytes. A method of LAF production is presented that permits the generation of a relatively homogeneous molecular species. LAF has an isoelectric point of 4.8 (range 4.7–4.9). The m.w.
James S Economou, Hyun S Shin
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Abstract Lipopolysaccharide-activated murine peritoneal macrophages elaborate lymphocyte-activating factor (LAF) which is mitogenic for murine thymocytes. A method of LAF production is presented that permits the generation of a relatively homogeneous molecular species. LAF has an isoelectric point of 4.8 (range 4.7–4.9). The m.w.
James S Economou, Hyun S Shin
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1987
The T lymphocyte receptor for antigen and histocompatibility molecules is a molecular complex comprised of five polypeptide chains. Both the 49KD alpha and 43KD beta chains are immunoglobulin-like and thus contain variable domains responsible for ligand binding.
C, Milanese +5 more
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The T lymphocyte receptor for antigen and histocompatibility molecules is a molecular complex comprised of five polypeptide chains. Both the 49KD alpha and 43KD beta chains are immunoglobulin-like and thus contain variable domains responsible for ligand binding.
C, Milanese +5 more
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Tempering lymphocyte activation
Science, 2020Immunodeficiency Diagnosis and treatment of inborn errors in immunity remain a challenge. Salzer et al. studied two siblings who were hospitalized for recurrent pediatric infections. Exome sequencing and functional analyses helped to identify homozygous loss-of-function mutations in genes encoding the protein HEM1 in both individuals.
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The immunological synapse: a molecular machine controlling T cell activation.
Science, 1999The specialized junction between a T lymphocyte and an antigen-presenting cell, the immunological synapse, consists of a central cluster of T cell receptors surrounded by a ring of adhesion molecules. Immunological synapse formation is now shown to be an
A. Grakoui +6 more
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Lymphocyte activation associated antigens.
Methods in cell biology, 2001N ...
Fattorossi, A, Battaglia, A, Ferlini, C
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Activation of Human B Lymphocytes
The Journal of Immunology, 1977Abstract The kinetics and mechanisms of suppression of the PWM-induced PFC response of human PB lymphocytes by Con A-activated suppressor cells were investigated. It was necessary that Con A suppressor cells be present early in the preocess of activation of human B cells toward antibody synthesis, but maximal suppression of the PFC ...
Barton F. Haynes, Anthony S. Fauci
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