Results 1 to 10 of about 108,523 (107)

Lymphocyte-Depletion Hodgkin's Disease [PDF]

New England Journal of Medicine, 1973
Abstract Study of 13 cases of lymphocyte-depletion Hodgkin's disease disclosed a distinctive clinicopathological entity of rapidly fatal disease with fever, pancytopenia, lymphocytopenia and abnormalities of hepatic function, frequently without peripheral lymphadenopathy.
Richard S Neiman, P J Rosen, Robert J Lukes   +2 more
exaly   +19 more sources

Homeostatic expansion as a barrier to lymphocyte depletion strategies. [PDF]

Curr Opin Organ Transplant, 2014
Following lymphodepletion, lymphocytes repopulate the immune space both through enhanced thymopoiesis and proliferation of residual nondepleted peripheral lymphocytes. The term homeostatic proliferation (alternatively homeostatic expansion or lymphopenia-induced proliferation) refers to the latter process.
Zwang NA, Turka LA.
europepmc   +4 more sources

Lymphocyte depletion in experimental hemorrhagic shock in Swine. [PDF]

J Inflamm (Lond), 2012
Abstract Background Hemorrhagic shock results in systemic activation of the immune system and leads to ischemia-reperfusion injury. Lymphocytes have been identified as critical mediators of the early innate immune response to ischemia-reperfusion injury, and immunomodulation of lymphocytes may prevent secondary ...
Hawksworth JS, Graybill C, Brown TS, Gillern SM, Wallace SM, Davis TA, Elster EA, Tadaki DK.   +7 more
europepmc   +5 more sources

Glutathione depletion in chronic lymphocytic leukemia B lymphocytes [PDF]

Blood, 1992
Abstract Glutathione (GSH) content may be the major determinant of a cell's sensitivity to cytotoxic alkylating agents. In the present study, the GSH concentration was determined in lymphocytes isolated from the blood of normal subjects and patients with chronic lymphocytic leukemia (CLL).
R, Silber, C M, Farber, E, Papadopoulos, D, Nevrla, L, Liebes, M, Bruck, R, Brown, Z N, Canellakis   +7 more
openaire   +3 more sources

Lymphocyte-Depleted Thymic Remnants [PDF]

American Journal of Clinical Pathology, 2009
Abstract The head and neck region is a frequent site for potentially confusing incidental benign findings not related to the primary pathologic process and having no impact on patient prognosis. Several lesions are thymic in origin. We report 3 cases of lymphocyte-poor thymic remnants identified in central cervical (level VI) lymph node ...
Geoffrey A. Talmon, Jean E. Lewis
openaire   +1 more source

The treatment resistance of lymphocyte depleted Hodgkin's disease [PDF]

Cancer, 1980
Lymphocyte-depleted Hodgkin's Disease (LDHD) is a very aggressive form of cancer that presents at an advanced stage and for which no increase in overall survival has been demonstrated with the advent of multiple agent chemotherapy. All cases of Hodgkin's disease diagnosed in the Province of Manitoba between 1971 and 1977 were reviewed.
S, Riddell, B, Weinerman, S, Kemel, H, Schipper, G, Vadas   +4 more
openaire   +2 more sources

Lymphocyte homeostasis following therapeutic lymphocyte depletion in multiple sclerosis

European Journal of Immunology, 2005
Following lymphocyte depletion, homeostatic mechanisms drive the reconstitution of lymphocytes. We prospectively studied this process in 16 patients for 1 year after a single pulse of treatment with Campath-1H, a humanised anti-CD52 monoclonal antibody. We observed two phases of lymphocyte reconstitution.
Cox, A, Thompson, SA, Jones, J, Robertson, V, Hale, G, Waldmann, H, Compston, D, Coles, A   +7 more
openaire   +3 more sources

Parenteral Feeding Depletes Pulmonary Lymphocyte Populations [PDF]

Journal of Parenteral and Enteral Nutrition, 2009
Background: The effect of parenteral nutrition (PN) on lymphocyte mass in the lung is unknown, but reduced mucosal lymphocytes are hypothesized to play a role in the reduced immunoglobulin A–mediated immunity in both gut and lung. The ability to transfer and track cells between mice may allow study of diet‐induced mucosal immune function.
Joshua L, Hermsen, F Enrique, Gomez, Yoshifumi, Sano, Woodae, Kang, Yoshinori, Maeshima, Kenneth A, Kudsk   +5 more
openaire   +2 more sources

Adjuvant Arthritis in T Lymphocyte Depleted Rats

Experimental Biology and Medicine, 1976
Markedly T lymphocyte depleted rats were prepared by thymectomy, irradiation, and repopulation by bone marrow hematopoietic and lymphoid cells. Such rats had persistent T lymphopenia of about 20% of normal. When T depleted and normal rats were injected with adjuvant, all animals developed arthritis but with slightly less severity in the T depleted ...
J W, Hollingsworth, D S, Greenberg, M, Dawson   +2 more
openaire   +2 more sources

Confirmation of CD19+ B-Lymphocyte Depletion Prior to Intake of the Second Dose of Ocrelizumab in Multiple Sclerosis Patients. [PDF]

Biomedicines, 2023
Radmilo M, Pavelin S, Vujović I, Šoda J, Rogić Vidaković M.   +4 more
europepmc   +1 more source