Results 11 to 20 of about 112,464 (281)

Impact of alemtuzumab-mediated lymphocyte depletion on SIV reservoir establishment and persistence. [PDF]

PLoS Pathog
Persistence of the rebound-competent viral reservoir (RCVR) within the CD4+ T cell compartment of people living with HIV remains a major barrier to HIV cure.
Varco-Merth B, Chaunzwa M, Duell DM, Marenco A, Goodwin W, Dannay R, Nekorchuk M, Shao D, Busman-Sahay K, Fennessey CM, Silipino L, Hull M, Bosche WJ, Fast R, Oswald K, Shoemaker R, Bochart R, MacAllister R, Labriola CS, Smedley JV, Axthelm MK, Davenport MP, Edlefsen PT, Estes JD, Keele BF, Lifson JD, Lewin SR, Picker LJ, Okoye AA.   +28 more
europepmc   +5 more sources

Evaluation of bursal lymphoid depletion: comparison between the conventional histology method and digital lymphocyte depletion evaluation system

Pesquisa Veterinária Brasileira, 2014
: Fifty-five bursa of Fabricius (BF) were evaluated by optical microscopy for three different avian histopathologists (H1, H3 and H4) to determine the degree of lymphoid depletion.
Lucas B. Moraes, Francielli C. Zimermann, Carlos T.P. Salle, Daiane Carvalho, Hamilton L.S. Moraes, Fernando S. Osório, Felipe O. Salle, Luiz C.B. Fallavena   +7 more
core   +2 more sources

Lymphocyte Depletion Rate as a Biomarker of Radiation Dose to Circulating Lymphocytes During Fractionated Partial-Body Radiation Therapy. [PDF]

Adv Radiat Oncol, 2022
PURPOSE: Radiation causes exponential depletion of circulating lymphocyte populations; in turn, radiation-induced lymphopenia is associated with worse survival for many solid tumors, possibly owing to attenuated antitumor immune responses.
Ellsworth SG, Yalamanchali A, Lautenschlaeger T, Grossman SA, Grassberger C, Lin SH, Mohan R.   +6 more
europepmc   +4 more sources

Circulating LOXL₂ Levels Reflect Severity of Intestinal Fibrosis and GALT CD4⁺ T Lymphocyte Depletion in Treated HIV Infection. [PDF]

Pathog Immun, 2017
Background: Incomplete immune reconstitution may occur despite successful antiretroviral therapy (ART). Gut-associated lymphoid tissue (GALT) fibrosis may contribute via local CD4+ T lymphocyte depletion, intestinal barrier disruption, microbial ...
Seang S, Somasunderam A, Nigalye M, Somsouk M, Schacker TW, Sanchez JL, Hunt PW, Utay NS, Lake JE.   +8 more
europepmc   +4 more sources

Using major histocompatibility complex (MHC) II expression to predict antitumor response to CD4 + lymphocyte depletion. [PDF]

Sci Rep
Immunotherapy targeting CD4 + FoxP3 + regulatory T cells (Tregs) through CD4 + lymphocyte depletion is being investigated as cancer treatment. This study examines the efficacy and limitations of CD4 depletion across various cancer models. We examined CD4
Wang Y, Kim M, Su S, Halwatura L, You S, Kim HL.   +5 more
europepmc   +3 more sources

Evaluation of thymic lymphocyte loss of broiler using Digital Analysis of the Lymphoid Depletion System (ADDL)

Pesquisa Veterinária Brasileira
: The thymus is a lymphoid organ and usually evaluated for the degree of lymphocyte loss with subjective histological techniques. This study aimed to adapt and to apply of the digital analysis of the lymphoid depletion system (ADDL) in the thymus in ...
Gabriela Zottis Chitolina, Daiane Carvalho, Fernando Santos Osório, Carlos Tadeu Pippi Salle, Hamilton Luiz de Souza Moraes, Lucas Brunelli de Moraes, Luiz Cesar Bello Fallavena, Juliana Inês Herpich   +7 more
core   +2 more sources

The Lymphocyte Depletion in Patients with Acute Ischemic Stroke Associated with Poor Neurologic Outcome. [PDF]

Int J Gen Med, 2021
Cep Juli,1,2 Henhen Heryaman,1 Arnengsih Nazir,1 Eng-Tat Ang,3 Irma Ruslina Defi,4 Uni Gamayani,2 Nur Atik5 1Doctoral Program, Faculty of Medicine, Padjadjaran University, Bandung, Indonesia; 2Department of Neurology, Dr.
Juli C, Heryaman H, Nazir A, Ang ET, Defi IR, Gamayani U, Atik N.   +6 more
europepmc   +2 more sources

Pseudorabies virus infection induces lymphocyte depletion associated with cellular apoptosis and endoplasmic reticulum stress in the mouse spleen. [PDF]

BMC Vet Res
Background The spleen is a highly organized lymphoid organ with a critical role in antimicrobial immune responses. Pseudorabies virus (PRV) is widely recognized for its ability to induce immunosuppression, with the spleen being one of the primary ...
Liu K, Xin H, Meng K, Zhao L, Lin S, Chen W, Xie Q, Zhu T.   +7 more
europepmc   +2 more sources

Early relapse during B lymphocyte depletion of children with frequently relapse /steroid dependent nephrotic syndrome after rituximab treatment. [PDF]

BMC Nephrol
Background Patients with frequent relapsing or steroid-dependent nephrotic syndrome (FRSDNS) often maintain remission during the period of B lymphocyte depletion following rituximab (RTX) administration. However, a subset of patients may experience early
Tu J, Wan L, Li H, Chen C.
europepmc   +2 more sources

Radiation-Induced Lymphopenia Risks of Photon Versus Proton Therapy for Esophageal Cancer Patients [PDF]

International Journal of Particle Therapy, 2021
Purpose: To assess possible differences in radiation-induced lymphocyte depletion for esophageal cancer patients being treated with the following 3 treatment modalities: intensity-modulated radiation therapy (IMRT), passive scattering proton therapy ...
Saba Ebrahimi, BSc, Gino Lim, PhD, Amy Liu, MSc, Steven H. Lin, MD, PhD, Susannah G. Ellsworth, MD, Clemens Grassberger, PhD, Radhe Mohan, PhD, Wenhua Cao, PhD   +7 more
doaj   +1 more source