Results 11 to 20 of about 115,860 (261)
Advances in tumor-infiltrating B lymphocytes
Central European Journal of ImmunologyIn the landscape of tumor immunotherapy, T cell-mediated immune responses have consistently captured the attention, while the contributions of B cells have been neglected.
Yule Zhang +4 more
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Tumor-infiltrating lymphocytes for melanoma immunotherapy
OncoImmunology, 2023 Oliver Kepp +3 more
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Tumor Infiltrating Lymphocytes in Ovarian Cancer [PDF]
Asian Pacific Journal of Cancer Prevention, 2015 Several improvements in ovarian cancer treatment have been achieved in recent years, both in surgery and in combination chemotherapy with targeting. However, ovarian tumors remain the women's cancers with highest mortality rates. In this scenario, a pivotal role has been endorsed to the immunological environment and to the immunological mechanisms ...
GASPARRI, MARIALUISA +8 more
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Tumor-Infiltrating Lymphocytes in Melanoma [PDF]
Current Oncology Reports, 2012 Adoptive cell therapy using tumor-infiltrating lymphocytes (TIL) is arguably the most effective treatment for patients with metastatic melanoma. With higher response rates than ipilimumab or IL-2, and longer durations of response than vemurafenib, TIL therapy carries the potential to transform current outcomes in melanoma, while also defining the way ...
Sylvia, Lee, Kim, Margolin
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Tumor-infiltrating lymphocytes in the immunotherapy era [PDF]
Cellular & Molecular Immunology, 2020 The clinical success of cancer immune checkpoint blockade (ICB) has refocused attention on tumor-infiltrating lymphocytes (TILs) across cancer types. The outcome of immune checkpoint inhibitor therapy in cancer patients has been linked to the quality and magnitude of T cell, NK cell, and more recently, B cell responses within the tumor microenvironment.
Sterre T, Paijens +3 more
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The role of tumor-infiltrating lymphocytes in cholangiocarcinoma
Journal of Experimental & Clinical Cancer Research, 2022 AbstractCholangiocarcinoma (CCA) is the second most common primary liver cancer and associated with a dismal prognosis due to the lack of an efficient systemic therapy. In contrast to other cancers, new immunotherapies have demonstrated unsatisfactory results in clinical trials, underlining the importance of a deeper understanding of the special tumor ...
Dong Liu +8 more
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The biologic importance of tumor‐infiltrating lymphocytes [PDF]
Journal of Cutaneous Pathology, 2010 Detailed pathologic analysis has delineated a close association between intratumoral CD 8+ cytotoxic T cells and favorable clinical outcomes in diverse cancers. Conversely, the presence at tumor sites of negative immune regulatory elements, such as FoxP 3+ T cells (Tregs) and PD‐1/PD‐L1 co‐stimulatory molecules, is closely associated with inferior ...
F Stephen, Hodi, Glenn, Dranoff
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Journal of Immunology Research, 2018 Objective. This study aimed to investigate the correlation of CD4+/PD-1+ or CD4+/PD-1− tumor-infiltrating lymphocytes with pathological characteristics in breast cancer patients. Methods.
Yan-Jie Zhao +10 more
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Journal of Ovarian Research, 2019 Background PD-L1 expression levels determined by immunostaining are known to be related to the survival rate and prognosis of patients with various types of cancers, as well as to the therapeutic response to immune checkpoint inhibitors.
Ki Hyung Kim +7 more
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Zhongguo aizheng zazhi, 2021 Background and purpose: Programmed death 1 (PD-1) plays an important role in the regulation of peripheral immune tolerance. The expression of PD-1 in tumor-infiltrating lymphocytes of hepatocellular carcinoma (HCC) and the relationship between PD-1 ...
肖 锋 +4 more
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