Results 11 to 20 of about 115,529 (261)
CD8+ T-cell lymphocytes infiltration predict clinical outcomes in Wilms’ tumor
Tumor Biology, 2020 The abundance and location of CD8+ tumor-infiltrating lymphocytes demonstrate important facets of the anticancer immune response. CD8-expressing lymphocytes have been used in immunotherapy for multiple cancers.
Keykhosro Mardanpour +4 more
doaj +1 more source
Tumor-infiltrating lymphocytes in the immunotherapy era [PDF]
Cellular & Molecular Immunology, 2020 The clinical success of cancer immune checkpoint blockade (ICB) has refocused attention on tumor-infiltrating lymphocytes (TILs) across cancer types. The outcome of immune checkpoint inhibitor therapy in cancer patients has been linked to the quality and magnitude of T cell, NK cell, and more recently, B cell responses within the tumor microenvironment.
Sterre T, Paijens +3 more
openaire +2 more sources
The role of tumor-infiltrating lymphocytes in cholangiocarcinoma
Journal of Experimental & Clinical Cancer Research, 2022 AbstractCholangiocarcinoma (CCA) is the second most common primary liver cancer and associated with a dismal prognosis due to the lack of an efficient systemic therapy. In contrast to other cancers, new immunotherapies have demonstrated unsatisfactory results in clinical trials, underlining the importance of a deeper understanding of the special tumor ...
Dong Liu +8 more
openaire +5 more sources
Life, 2020 Immunotherapy is a highly promising approach for the treatment of gastric cancer, the third-leading cause of overall cancer death worldwide. In particular, tumor-infiltrating lymphocytes and peripheral blood mononuclear cells are believed to mediate host
Wei-Ming Chen +6 more
doaj +1 more source
Biomedicines, 2022 Oropharynx squamous cell carcinoma (OPSCC) is of special interest because human papilloma virus (HPV) and/or smoking cause this disease. Influxes of inflammatory cells into such tumors are known to vary with prognoses.
Hilde Haave +7 more
doaj +1 more source
The biologic importance of tumor‐infiltrating lymphocytes [PDF]
Journal of Cutaneous Pathology, 2010 Detailed pathologic analysis has delineated a close association between intratumoral CD 8+ cytotoxic T cells and favorable clinical outcomes in diverse cancers. Conversely, the presence at tumor sites of negative immune regulatory elements, such as FoxP 3+ T cells (Tregs) and PD‐1/PD‐L1 co‐stimulatory molecules, is closely associated with inferior ...
F Stephen, Hodi, Glenn, Dranoff
openaire +2 more sources
Ukrainian Scientific Medical Youth Journal, 2019 The article summarizes data and presents own study about the value of tumor-infiltrating lymphocytes as a prognostic factor for breast cancer including triple negative breast cancer lacking estrogen and progesterone receptors and HER2\new amplification ...
Liubov Zakhartseva, Mariia Yanovytska
doaj +1 more source
Tumor-infiltrating lymphocytes in triple negative breast cancer
Patologìâ, 2020 The aim of this retrospective study is to assess the prognostic value of tumor-infiltrating lymphocytes in triple negative breast carcinomas that lack both estrogen, progesterone receptors and Her2 amplification.
L. M. Zakhartseva, M. O. Yanovytska
doaj +1 more source
Journal of Immunology Research, 2018 Objective. This study aimed to investigate the correlation of CD4+/PD-1+ or CD4+/PD-1− tumor-infiltrating lymphocytes with pathological characteristics in breast cancer patients. Methods.
Yan-Jie Zhao +10 more
doaj +1 more source
Journal of Ovarian Research, 2019 Background PD-L1 expression levels determined by immunostaining are known to be related to the survival rate and prognosis of patients with various types of cancers, as well as to the therapeutic response to immune checkpoint inhibitors.
Ki Hyung Kim +7 more
doaj +1 more source