Results 21 to 30 of about 115,529 (261)
Background and purpose: Programmed death 1 (PD-1) plays an important role in the regulation of peripheral immune tolerance. The expression of PD-1 in tumor-infiltrating lymphocytes of hepatocellular carcinoma (HCC) and the relationship between PD-1 ...
肖 锋 +4 more
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Association between tumor-infiltrating lymphocytes and sentinel lymph node positivity in thin melanoma [PDF]
: Background: Sentinel lymph node biopsy in thin invasive primary cutaneous melanoma (up to 1mm thick) is a controversial subject. The presence of tumor-infiltrating lymphocytes could be a factor to be considered in the decision to perform this ...
Fernando De Marco dos Santos +5 more
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Tumor-infiltrating lymphocytes and breast cancer: Beyond the prognostic and predictive utility
The importance of the immune system as a potent anti-tumor defense has been consolidated in recent times, and novel immune-related therapies are today demonstrating a strong clinical benefit in the setting of several solid neoplasms.
Andrea Ravelli +13 more
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Purpose: This study aimed to elucidate the clinicopathological significance and prognostic role of tumor-infiltrating lymphocytes in colorectal cancer. Methods: The immunohistochemistry of CD3 and CD8 was performed on 265 human colorectal cancer tissues ...
Young San Ko, Jung-Soo Pyo
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Background/Aims: T-bet, a member of the T-box family of transcription factors, is a key marker of type I immune response within the tumor microenvironment, and has been previously reported by us to serve as an important prognostic indicator for human ...
Yun Xu +9 more
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IntroductionTumor-infiltrating T lymphocytes in the tumor microenvironment are critical factors influencing the prognosis and chemotherapy outcomes. As a Chinese herbal medicine, Marsdenia tenacissima extract (MTE) has been widely used to treat cancer in
Ben Yi +15 more
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CTL Attenuation Regulated by PS1 in Cancer-Associated Fibroblast
Objective: Cancer-associated fibroblasts (CAFs) were associated with tumor progression in the tumor microenvironment (TME). However, their immunosuppressive roles in protecting cancer cells from the attack by cytotoxic T lymphocytes (CTLs) are not fully ...
Hongyu Zhang +23 more
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The interaction of CNS tumors with infiltrating lymphocytes plays an important role in their initiation and progression and might be related to therapeutic responses.
Sepehr Safaei +4 more
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Objective: To conduct a morphological evaluation quantitatively of two types of tumor-infiltrating lymphocyte populations, including those located in the stroma and intraepithelial cancer structures, in patients with colorectal cancer.
Amna Ameer +3 more
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Characteristics of lymphocyte-infiltrating papillary thyroid cancer
Background: The tumor-promoting or tumor-suppressing role of tumor-associated lymphocytes remains a subject of debate. We examined thyroid cancer data from The Cancer Genome Atlas in an attempt to define the relationship between lymphocyte infiltrates ...
Chi-Yu Kuo +3 more
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