Results 21 to 30 of about 311,006 (351)
Frontiers in Immunology, 2022 The clinical success of immunotherapy has revolutionized the treatment of cancer patients, bringing renewed attention to tumor-infiltrating lymphocytes (TILs) of various cancer types.
Ziyi Bai +5 more
semanticscholar +1 more source
Tumor-infiltrating lymphocytes for treatment of solid tumors: It takes two to tango?
Frontiers in Immunology, 2022 Tumor-infiltrating lymphocytes (TILs), frontline soldiers of the adaptive immune system, are recruited into the tumor site to fight against tumors. However, their small number and reduced activity limit their ability to overcome the tumor. Enhancement of
M. Kazemi +6 more
semanticscholar +1 more source
Frontiers in Immunology, 2021 Primary liver cancer (PLC) is one of the most common malignancies in China, where it ranks second in mortality and fifth in morbidity. Currently, liver transplantation, hepatic tumor resection, radiofrequency ablation, and molecular-targeted agents are ...
Xiaoqin Zheng +3 more
semanticscholar +1 more source
CD8+ T-cell lymphocytes infiltration predict clinical outcomes in Wilms’ tumor
Tumor Biology, 2020 The abundance and location of CD8+ tumor-infiltrating lymphocytes demonstrate important facets of the anticancer immune response. CD8-expressing lymphocytes have been used in immunotherapy for multiple cancers.
Keykhosro Mardanpour +4 more
doaj +1 more source
Increased expression of programmed death ligand 1 (PD-L1) in human pituitary tumors [PDF]
, 2016 PURPOSE: Subsets of pituitary tumors exhibit an aggressive clinical courses and recur despite surgery, radiation, and chemotherapy. Because modulation of the immune response through inhibition of T-cell checkpoints has led to durable clinical responses ...
Agar, Nathalie Y. R. +13 more
core +6 more sources
Epigenetic quantification of tumor-infiltrating T-lymphocytes [PDF]
Epigenetics, 2011 The immune system plays a pivotal role in tumor establishment. However, the role of T-lymphocytes within the tumor microenvironment as major cellular component of the adaptive effector immune response and their counterpart, regulatory T-cells (Treg), responsible for suppressive immune modulation, is not completely understood.
Alexander Mustea +13 more
openaire +3 more sources
Life, 2020 Immunotherapy is a highly promising approach for the treatment of gastric cancer, the third-leading cause of overall cancer death worldwide. In particular, tumor-infiltrating lymphocytes and peripheral blood mononuclear cells are believed to mediate host
Wei-Ming Chen +6 more
doaj +1 more source
Can the plasma PD-1 levels predict the presence and efficiency of tumor-infiltrating lymphocytes in patients with metastatic melanoma? [PDF]
, 2019 Background: The immune response in melanoma patients is locally affected by presence of tumor-infiltrating lymphocytes (TILs), generally divided into brisk, nonbrisk, and absent.
Badalamenti G. +11 more
core +1 more source
Tumor-infiltrating lymphocytes in triple negative breast cancer
Patologìâ, 2020 The aim of this retrospective study is to assess the prognostic value of tumor-infiltrating lymphocytes in triple negative breast carcinomas that lack both estrogen, progesterone receptors and Her2 amplification.
L. M. Zakhartseva, M. O. Yanovytska
doaj +1 more source
Tumor-infiltrating T lymphocytes: friends or foes? [PDF]
Laboratory Investigation, 2006 The prognostic significance of tumor-infiltrating lymphocytes (TILs) has been a longstanding topic of debate. In cases where TILs have improved patient outcome, T lymphocytes are recognized as the main effectors of antitumor immune responses. However, recent studies have revealed that a subset of CD4(+) T cells, referred to as CD4(+)CD25(+) regulatory ...
Ping Yu, Yang Xin Fu
openaire +2 more sources