Results 151 to 160 of about 2,052,161 (361)

Endogenous IL-7 Variation in Relation to Lymphocyte Subtypes in Septic Patients

Medicina
Background and Objectives: Sepsis triggers a complex immune response, disrupting the balance between pro- and anti-inflammatory signals and causing widespread immune cell apoptosis.
Raluca-Ștefania Fodor, Alice Drăgoescu, Oana Coman, Adina Huțanu, Anca Bacârea, Bianca-Liana Grigorescu   +5 more
doaj   +1 more source

Up-regulation of gap junction in peripheral blood T lymphocytes contributes to the inflammatory response in essential hypertension

, 2017
Xin Ni, Wang Ai, Liang Zhang, Liya Shan, Haichao Zhang, Li Li, Jun‐Qiang Si, Jian Luo, Xinzhi Li, Ketao Ma   +9 more
openalex   +2 more sources

Ice Lithography: Recent Progress Opens a New Frontier of Opportunities

Advanced Functional Materials, EarlyView.
This review focuses on recent advancements in ice lithography, including breakthroughs in compatible precursors and substrates, processes and applications, hardware, and digital methods. Moreover, it offers a roadmap to uncover innovation opportunities for ice lithography in fields such as biological, nanoengineering and microsystems, biophysics and ...
Bingdong Chang, Gwendoline A. E. Anand, Rubaiyet Haque, Dylan A. Chiaro, Mona Sharma, Andrew R. Williams, Frank Niklaus, Daryl W. Yee, Gavin M. King, Anpan Han   +9 more
wiley   +1 more source

Pipelines for lymphocyte homeostasis maintenance during cancer immunotherapy

Frontiers in Immunology
In general, increasing lymphocyte entry into tumor microenvironment (TME) and limiting their efflux will have a positive effect on the efficacy of immunotherapy.
Bensu Du, Jin Geng, Bin Wu, Houru Wang, Ru Luo, Hanmeng Liu, Rui Zhang, Fengping Shan, Lei Liu, Shuling Zhang   +9 more
doaj   +1 more source

Bimetallic Nanoreactor Activates cGAS‐STING Pathway via mtDNA Release for Cancer Metalloimmunotherapy

Advanced Functional Materials, EarlyView.
A bimetallic Mn–Ca nanoreactor (MCC) is developed as a non‐nucleotide STING nanoagonist for cancer metalloimmunotherapy. MCC induces Ca2+ overload and hydroxyl radical generation, resulting in mitochondrial damage and mtDNA release. The released mtDNA cooperates with Mn2+ to robustly activate cGAS–STING signaling.
Xin Wang Mo, Nguyen Thi Nguyen, LiLi Guo, Ngoc Man Phan, Hyunsu Shin, Tae‐il. Kim, Yu Seok Youn, Jaeyun Kim   +7 more
wiley   +1 more source

Physalin F, a Potent Inhibitor of Lymphocyte Function, Is a Calcineurin Inhibitor and Has Synergistic Effect with Dexamethasone

Molecules
The dysregulation of immune responses are responsible for the development of several diseases, such as allergic and autoimmune diseases. The medications used to treat these conditions have numerous side effects, creating the need for new drugs. Physalins
Dahara Keyse Carvalho Silva, Laura Beatriz da Cruz Novo, Ivone Maria Ribeiro, Breno Cardim Barreto, Luiza Carolina França Opretzka, Cássio Santana Meira, Milena Botelho Pereira Soares   +6 more
doaj   +1 more source

The Immune System [PDF]

, 1995
Modern biotherapy has been in use for some 30 years. The first types of biotherapy were nonspecific stimulators of the immune response, but advances in genetic engineering are allowing the mass production of pure biological products which are now being ...
Gallucci, Betty Bierut, McCarthy, Donna O.   +1 more
core   +1 more source

Predicting Survival of Patients with Nonmetastatic Breast Cancer Based on Fibrinogen-to-Albumin Ratio and Lymphocyte-to-Monocyte Ratio: A Nomogram-Based Assessment [PDF]

, 2023
Xiaoyu Chen, Zhi‐Qing Long, Han-Ying Huang, Wen Wen, Fei Lin, Ling Guo, Huan‐Xin Lin   +6 more
openalex   +1 more source

Electrosynthesis of Bioactive Chemicals, From Ions to Pharmaceuticals

Advanced Functional Materials, EarlyView.
This review discusses recent advances in electrosynthesis for biomedical and pharmaceutical applications. It covers key electrochemical materials enabling precise delivery of ions and small molecules for cellular modulation and disease treatment, alongside catalytic systems for pharmaceutical synthesis.
Gwangbin Lee, Sojin Kim, Myeongeun Lee, Kyoungsuk Jin, Jimin Park   +4 more
wiley   +1 more source

Prognostic significance of blood immune cells in children with sepsis and establishment of a predictive model for PICU mortality: a retrospective study

Frontiers in Pediatrics
ObjectivesThis article aimed to investigate the correlation between blood immune cells and the prognosis in the early phase of pediatric sepsis and construct a prediction model for pediatric intensive care unit (PICU) mortality.MethodsA total of 348 ...
Mulan He, Qiuxia Meng, Zhixin Wei, Zhiyong Yang   +3 more
doaj   +1 more source